Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

Classification and Regression Trees.

1984 • 23,117 citations

Classification and Regression Trees.

1986 • 21,574 citations

Molecular portraits of human breast tumours

2000 • 15,445 citations

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

2001 • 10,602 citations

Myeloid-derived suppressor cells as regulators of the immune system

2009 • 6,165 citations

Repeated observation of breast tumor subtypes in independent gene expression data sets

2003 • 5,356 citations

Summaries of Affymetrix GeneChip probe level data

2003 • 4,927 citations

Macrophage Diversity Enhances Tumor Progression and Metastasis

2010 • 4,601 citations

Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study

2006 • 3,623 citations

Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer

2007 • 3,010 citations

Entrez Gene: gene-centered information at NCBI

2010 • 2,133 citations

Stromal gene expression predicts clinical outcome in breast cancer

2008 • 1,633 citations

Colony-Stimulating Factor 1 Promotes Progression of Mammary Tumors to Malignancy

2001 • 1,556 citations

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease.

1992 • 1,496 citations

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

2008 • 1,305 citations

CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages

2009 • 1,265 citations

Tumor-Associated Macrophages and Survival in Classic Hodgkin's Lymphoma

2010 • 1,218 citations

Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma.

1996 • 1,206 citations

Trophic macrophages in development and disease

2009 • 1,127 citations

A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

2004 • 1,127 citations

Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases

2003 • 1,049 citations

Macrophages Regulate the Angiogenic Switch in a Mouse Model of Breast Cancer

2006 • 1,020 citations

Induction of Mammary Tumors by Expression of Polyomavirus Middle T Oncogene: A Transgenic Mouse Model for Metastatic Disease

1992 • 812 citations

De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent

2005 • 785 citations

Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression

2005 • 752 citations

The transcriptional repressor Snail promotes mammary tumor recurrence

2005 • 714 citations

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF

2011 • 662 citations

Pharmacogenomic Predictor of Sensitivity to Preoperative Chemotherapy With Paclitaxel and Fluorouracil, Doxorubicin, and Cyclophosphamide in Breast Cancer

2006 • 654 citations

A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth

2009 • 631 citations

Reduced Inflammation in the Tumor Microenvironment Delays the Accumulation of Myeloid-Derived Suppressor Cells and Limits Tumor Progression

2007 • 613 citations

B-cell-derived lymphotoxin promotes castration-resistant prostate cancer

2010 • 596 citations

Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression

2010 • 582 citations

FcRγ Activation Regulates Inflammation-Associated Squamous Carcinogenesis

2010 • 541 citations

Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer

2009 • 516 citations

Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity

2010 • 477 citations

<title>Normalization for cDNA microarry data</title>

2001 • 458 citations

Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis

2008 • 450 citations

Tumor-Associated Macrophages Press the Angiogenic Switch in Breast Cancer

2007 • 437 citations

The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time

2010 • 411 citations

Predominant infiltration of macrophages and CD8⁺T Cells in cancer nests is a significant predictor of survival in stage IV nonsmall cell lung cancer

2008 • 359 citations

Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

2010 • 336 citations

Residual Ductal Carcinoma In Situ in Patients With Complete Eradication of Invasive Breast Cancer After Neoadjuvant Chemotherapy Does Not Adversely Affect Patient Outcome

2007 • 277 citations

Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival

2008 • 275 citations

Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome

2010 • 254 citations

CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis

2009 • 246 citations

Prognostic Significance of Stromal Platelet-Derived Growth Factor β-Receptor Expression in Human Breast Cancer

2009 • 234 citations

Lymphocytes in cancer development: Polarization towards pro-tumor immunity

2009 • 233 citations

Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice

2008 • 213 citations

Profile of Immune Cells in Axillary Lymph Nodes Predicts Disease-Free Survival in Breast Cancer

2005 • 210 citations

Invasion of Human Breast Cancer Cells In vivo Requires Both Paracrine and Autocrine Loops Involving the Colony-Stimulating Factor-1 Receptor

2009 • 204 citations

Evaluation of a 30-Gene Paclitaxel, Fluorouracil, Doxorubicin, and Cyclophosphamide Chemotherapy Response Predictor in a Multicenter Randomized Trial in Breast Cancer

2010 • 201 citations

The Macrophage Colony-Stimulating Factor 1 Response Signature in Breast Carcinoma

2009 • 200 citations

Detection of M2-Macrophages in Uveal Melanoma and Relation with Survival

2010 • 196 citations

Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages

2007 • 149 citations

Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer

2008 • 130 citations

Impaired tumor growth in colony-stimulating factor 1 (CSF-1)-deficient, macrophage-deficientop/op mouse: Evidence for a role of CSF-1-dependent macrophages in formation of tumor stroma

1996 • 118 citations

CD49d Is a New Marker for Distinct Myeloid-Derived Suppressor Cell Subpopulations in Mice

2010 • 116 citations

Phase III Trials of Eribulin Mesylate (E7389) in Extensively Pretreated Patients With Locally Recurrent or Metastatic Breast Cancer

2010 • 105 citations

JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia

2009 • 104 citations

Analysis of stromal signatures in the tumor microenvironment of ductal carcinoma in situ

2009 • 102 citations

M‐CSF (monocyte colony stimulating factor) and M‐CSF receptor expression by breast tumour cells: M‐CSF mediated recruitment of tumour infiltrating monocytes?

1992 • 100 citations

Coordinate Expression of Colony-Stimulating Factor-1 and Colony-Stimulating Factor-1-Related Proteins Is Associated with Poor Prognosis in Gynecological and Nongynecological Leiomyosarcoma

2009 • 89 citations

Altered Cytoplasmic-to-Nuclear Ratio of Survivin Is a Prognostic Indicator in Breast Cancer

2008 • 86 citations

Analysis of Immune Cell Infiltrates during Squamous Carcinoma Development

2006 • 28 citations