Analysis of stromal signatures in the tumor microenvironment of ductal carcinoma in situ

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion

2005 • 3,543 citations

Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

2007 • 3,082 citations

Putting tumours in context

2001 • 2,145 citations

Friends or foes — bipolar effects of the tumour stroma in cancer

2004 • 1,742 citations

Carcinoma-associated fibroblasts stimulate tumor progression of initiated human epithelium

2000 • 1,445 citations

TUMOR STROMA AND REGULATION OF CANCER DEVELOPMENT

2006 • 972 citations

Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds

2004 • 931 citations

A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth

2009 • 631 citations

Incidence of and Treatment for Ductal Carcinoma In Situ of the Breast

1996 • 600 citations

Heterotypic Signaling between Epithelial Tumor Cells and Fibroblasts in Carcinoma Formation

2001 • 554 citations

Tumor–stroma interactions

2004 • 444 citations

Continued local recurrence of carcinoma 15–25 years after a diagnosis of low grade ductal carcinoma in situ of the breast treated only by biopsy

1995 • 432 citations

Role of the stromal microenvironment in carcinogenesis of the prostate

2003 • 362 citations

Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast.

1999 • 361 citations

Microvessel Density and Distribution in Ductal Carcinoma In Situ of the Breast

1994 • 287 citations

Targeting HER-2/neuin Early Breast Cancer Development Using Dendritic Cells with Staged Interleukin-12 Burst Secretion

2007 • 260 citations

Targeting the tumor microenvironment

2007 • 217 citations

Abrogated Response to Cellular Stress Identifies DCIS Associated with Subsequent Tumor Events and Defines Basal-like Breast Tumors

2007 • 213 citations

The Macrophage Colony-Stimulating Factor 1 Response Signature in Breast Carcinoma

2009 • 200 citations

Role of COX-2 in epithelial–stromal cell interactions and progression of ductal carcinoma in situ of the breast

2009 • 195 citations

Determination of Stromal Signatures in Breast Carcinoma

2005 • 195 citations

Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity

2007 • 183 citations

Tumor-Specific Low Molecular Weight Forms of Cyclin E Induce Genomic Instability and Resistance to p21, p27, and Antiestrogens in Breast Cancer

2004 • 153 citations

The fibromatosis signature defines a robust stromal response in breast carcinoma

2008 • 113 citations

Sporadic Invasive Breast Carcinomas With Medullary Features Display a Basal-like Phenotype

2007 • 65 citations

Molecular subtypes of breast cancer and amplification of topoisomerase IIα: predictive role in dose intensive adjuvant chemotherapy

2006 • 62 citations

The assessment of angiogenesis and fibroblastic stromagenesis in hyperplastic and pre-invasive breast lesions

2008 • 57 citations

Impact of Randomized Clinical Trial Results in the National Comprehensive Cancer Network on the Use of Tamoxifen After Breast Surgery for Ductal Carcinoma in Situ

2007 • 46 citations

Radial scars of the breast and breast carcinomas have similar alterations in expression of factors involved in vascular stroma formation

2002 • 43 citations

Comedo-Ductal carcinoma in situ: A paradoxical role for programmed cell death

2008 • 32 citations

Novel Clinical Trial Designs for Treatment of Ductal Carcinoma In Situ of the Breast with Trastuzumab (Herceptin)

2007 • 22 citations