Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

2005 • 7,244 citations

Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study

2006 • 3,623 citations

Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma

2004 • 2,644 citations

Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer

2005 • 2,221 citations

A Comparison of Letrozole and Tamoxifen in Postmenopausal Women with Early Breast Cancer

2005 • 1,530 citations

A Human Protein Atlas for Normal and Cancer Tissues Based on Antibody Proteomics

2005 • 1,411 citations

Meeting Highlights: International Expert Consensus on the Primary Therapy of Early Breast Cancer 2005

2005 • 1,131 citations

Global histone modification patterns predict risk of prostate cancer recurrence

2005 • 1,063 citations

Automated subcellular localization and quantification of protein expression in tissue microarrays

2002 • 764 citations

Quantification of immunohistochemistry—issues concerning methods, utility and semiquantitative assessment II

2006 • 570 citations

Immunohistochemistry of Estrogen and Progesterone Receptors Reconsidered

2005 • 418 citations

ATAC trial update

2005 • 393 citations

Quantification of immunohistochemistry—issues concerning methods, utility and semiquantitative assessment I

2006 • 306 citations

Automated Quantitative Analysis (AQUA) of In Situ Protein Expression, Antibody Concentration, and Prognosis

2005 • 275 citations

Novel Prognostic Immunohistochemical Biomarker Panel for Estrogen Receptor–Positive Breast Cancer

2006 • 181 citations

Tumor classification by tissue microarray profiling: random forest clustering applied to renal cell carcinoma

2004 • 179 citations

Assessment of Interlaboratory Variation in the Immunohistochemical Determination of Estrogen Receptor Status Using a Breast Cancer Tissue Microarray

2002 • 164 citations

CA IX is an Independent Prognostic Marker in Premenopausal Breast Cancer Patients with One to Three Positive Lymph Nodes and a Putative Marker of Radiation Resistance

2006 • 135 citations

Two years of adjuvant tamoxifen in premenopausal patients with breast cancer: a randomised, controlled trial with long-term follow-up

2004 • 117 citations

Quantitative analysis of estrogen receptor heterogeneity in breast cancer

2007 • 111 citations

Automated quantitative analysis of estrogen receptor expression in breast carcinoma does not differ from expert pathologist scoring: a tissue microarray study of 3,484 cases

2007 • 105 citations

Quality Assurance in Immunohistochemistry

2002 • 104 citations

Altered Cytoplasmic-to-Nuclear Ratio of Survivin Is a Prognostic Indicator in Breast Cancer

2008 • 86 citations

Tissue microarrays: bridging the gap between research and the clinic

2005 • 68 citations

Assessment of Two Automated Imaging Systems in Evaluating Estrogen Receptor Status in Breast Carcinoma

2007 • 67 citations

Interobserver agreement for estrogen receptor immunohistochemical analysis in breast cancer: a comparison of manual and computer-assisted scoring methods

2004 • 62 citations

New perspectives into the biological and clinical relevance of oestrogen receptors in the human breast

2007 • 59 citations

Application of DNA microarray technology in determining breast cancer prognosis and therapeutic response

2005 • 59 citations

Immunohistochemical Evaluation of Hormone Receptors in Breast Cancer

2004 • 48 citations

Contribution of DNA and tissue microarray technology to the identification and validation of biomarkers and personalised medicine in breast cancer.

2007 • 39 citations

Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue microarray feasibility study

2008 • 35 citations

Adjuvant endocrine therapy

2003 • 26 citations