The transcriptional repressor Snail promotes mammary tumor recurrence
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References (50)
Global cancer statistics
2011 • 55,498 citations
Global Cancer Statistics, 2002
2005 • 17,966 citations
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene
1987 • 11,429 citations
Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2
2001 • 11,070 citations
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
2001 • 10,602 citations
Gene expression profiling predicts clinical outcome of breast cancer
2002 • 9,314 citations
Repeated observation of breast tumor subtypes in independent gene expression data sets
2003 • 5,356 citations
Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis
2004 • 3,727 citations
The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression
2000 • 3,504 citations
Efficacy and Safety of Trastuzumab as a Single Agent in First-Line Treatment of HER2-Overexpressing Metastatic Breast Cancer
2002 • 2,968 citations
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
2005 • 2,658 citations
The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells
2000 • 2,569 citations
Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases
1989 • 2,245 citations
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition
2004 • 1,530 citations
Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer.
1996 • 1,393 citations
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
2005 • 1,225 citations
The SLUG zinc-finger protein represses E-cadherin in breast cancer.
2002 • 991 citations
A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
2004 • 941 citations
Annual hazard rates of recurrence for breast cancer after primary therapy.
1996 • 833 citations
The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition
2001 • 611 citations
Correlation of Snail expression with histological grade and lymph node status in breast carcinomas
2002 • 577 citations
Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading.
1988 • 570 citations
Significance of ipsilateral breast tumour recurrence after lumpectomy
1991 • 556 citations
Patterns of relapse and survival following radical mastectomy.Analysis of 716 consecutive patients
1978 • 465 citations
Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma.
1993 • 398 citations
Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription
2005 • 373 citations
Treatment of lymph-node-negative, oestrogen-receptor-positive breast cancer: long-term findings from National Surgical Adjuvant Breast and Bowel Project randomised clinical trials
2004 • 358 citations
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis
2002 • 339 citations
Pak1 Phosphorylation of Snail, a Master Regulator of Epithelial-to-Mesenchyme Transition, Modulates Snail's Subcellular Localization and Functions
2005 • 265 citations
Prognostic molecular markers in early breast cancer
2004 • 245 citations
Local Failure Is Responsible for the Decrease in Survival for Patients With Breast Cancer Treated With Conservative Surgery and Postoperative Radiotherapy
1999 • 241 citations
The Akt Proto-oncogene Links Ras to Pak and Cell Survival Signals
2000 • 235 citations
Mechanisms of inactivation of E-cadherin in breast carcinoma: modification of the two-hit hypothesis of tumor suppressor gene
2001 • 223 citations
Twist Function Is Required for the Morphogenesis of the Cephalic Neural Tube and the Differentiation of the Cranial Neural Crest Cells in the Mouse Embryo
2002 • 220 citations
A novel doxycycline‐inducible system for the transgenic analysis of mammary gland biology
2002 • 201 citations
Separating favorable from unfavorable prognostic markers in breast cancer: the role of E-cadherin.
2000 • 170 citations
Role of Isolated Locoregional Recurrence of Breast Cancer: Results of Four Prospective Studies
2000 • 147 citations
Long-term results of local recurrence after breast conservation treatment for invasive breast cancer
2001 • 133 citations
Detection and clinical implications of early systemic tumor cell dissemination in breast cancer.
2003 • 130 citations
MUTATIONS AND CHROMOSOMAL REARRANGEMENTS AFFECTING THE EXPRESSION OF SNAIL, A GENE INVOLVED IN EMBRYONIC PATTERNING IN DROSOPHILA MELANOGASTER
1984 • 123 citations
Overview of treatment results with trastuzumab (Herceptin) in metastatic breast cancer
2001 • 111 citations
Transgenic oncogene mice. Tumor phenotype predicts genotype.
1991 • 100 citations
Targeting HER2: Recent developments and future directions for breast cancer patients
2001 • 94 citations
C-myc, not HER-2/neu, can predict recurrence and mortality of patients with node-negative breast cancer
2003 • 72 citations
The prognostic significance of epithelial-mesenchymal transition in breast cancer.
2003 • 70 citations
Targeting HER2: Recent developments and future directions for breast cancer patients
2001 • 70 citations
Menopausal status dependence of the timing of breast cancer recurrence after surgical removal of the primary tumour
2004 • 67 citations
Natural History of More Than 20 Years of Node-Positive Primary Breast Carcinoma Treated With Cyclophosphamide, Methotrexate, and Fluorouracil–Based Adjuvant Chemotherapy: A Study by the Cancer and Leukemia Group B
2003 • 65 citations
E-cadherin mRNA expression in breast carcinomas correlates with overall and disease-free survival.
1996 • 34 citations
Vimentin expression in breast carcinomas.
2003 • 12 citations
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