NELF, a Multisubunit Complex Containing RD, Cooperates with DSIF to Repress RNA Polymerase II Elongation

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Current protocols in molecular biology

1988 • 7,584 citations

Transcriptional regulation

1991 • 893 citations

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

1998 • 718 citations

Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro

1997 • 692 citations

Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase

1996 • 645 citations

CONTROL OF RNA INITIATION AND ELONGATION AT THE HIV-1 PROMOTER

1994 • 613 citations

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.

1985 • 575 citations

Purification of P-TEFb, a Transcription Factor Required for the Transition into Productive Elongation

1995 • 544 citations

5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II

1997 • 540 citations

Identification of multiple cyclin subunits of human P-TEFb

1998 • 512 citations

Reversible Phosphorylation of the C-terminal Domain of RNA Polymerase II

1996 • 498 citations

Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation

1999 • 482 citations

mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain

1997 • 467 citations

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

1998 • 460 citations

BASIC MECHANISMS OF TRANSCRIPT ELONGATION AND ITS REGULATION

1997 • 441 citations

Temporal Regulation of RNA Polymerase II by Srb10 and Kin28 Cyclin-Dependent Kinases

1998 • 400 citations

Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription invitro

1998 • 343 citations

Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation

1994 • 325 citations

A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix.

1996 • 324 citations

Elongin (SIII): A Multisubunit Regulator of Elongation by RNA Polymerase II

1995 • 320 citations

The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex.

1991 • 319 citations

Control of formation of two distinct classes of RNA polymerase II elongation complexes.

1992 • 295 citations

HIV-1 Tat protein promotes formation of more-processive elongation complexes.

1991 • 295 citations

NAT, a Human Complex Containing Srb Polypeptides that Functions as a Negative Regulator of Activated Transcription

1998 • 235 citations

5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole inhibits transcription elongation by RNA polymerase II in vitro

1989 • 225 citations

Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II

1997 • 223 citations

The inhibition of DRB (5,6-dichloro-1-β-d-ribofuranosylbenzimidazole) of hnRNA and mRNA production in HeLa cells

1976 • 204 citations

The C-terminal repeat domain of RNA polymerase II largest subunit is essential in vivo but is not required for accurate transcription initiation in vitro.

1988 • 190 citations

SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat.

1991 • 179 citations

Phosphorylation of C-terminal domain of RNA polymerase II is not required in basal transcription

1993 • 176 citations

Transcription factor IIE binds preferentially to RNA polymerase IIa and recruits TFIIH: a model for promoter clearance.

1994 • 176 citations

A CTD function linking transcription to splicing

1997 • 160 citations

An essential component of a C-terminal domain phosphatase that interacts with transcription factor IIF in Saccharomyces cerevisiae

1997 • 145 citations

FCP1, the RAP74-Interacting Subunit of a Human Protein Phosphatase That Dephosphorylates the Carboxyl-terminal Domain of RNA Polymerase IIO

1998 • 144 citations

Structure and Function of the Human Transcription Elongation Factor DSIF

1999 • 140 citations

The RNA polymerase II general elongation factors

1996 • 133 citations

A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes

1997 • 127 citations

A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription.

1995 • 123 citations

Inhibitors of transcription such as 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole and isoquinoline sulfonamide derivatives (H-8 and H-7) promote dephosphorylation of the carboxyl-terminal domain of RNA polymerase II largest subunit.

1994 • 122 citations

The Activity of COOH-terminal Domain Phosphatase Is Regulated by a Docking Site on RNA Polymerase II and by the General Transcription Factors IIF and IIB

1995 • 121 citations

A Previously Undetected MHC Gene with an Unusual Periodic Structure

1988 • 108 citations

The RNA polymerase II general elongation factors

1996 • 107 citations

Factors regulating the transcriptional elongation activity of RNA polymerase II

1998 • 105 citations

Transcription factor E4TF1 contains two subunits with different functions.

1990 • 82 citations

Interplay between positive and negative elongation factors: drawing a new view of DRB

1998 • 81 citations

Promoter-proximal stalling results from the inability to recruit transcription factor IIH to the transcription complex and is a regulated event

1998 • 76 citations

47 Analysis of SPT Genes: A Genetic Approach toward Analysis of TFIID, Histones, and Other Transcription Factors of Yeast

1992 • 65 citations

A Human RNA Polymerase II Transcription Termination Factor Is a SWI2/SNF2 Family Member

1998 • 53 citations

Purification of an RNA Polymerase II Transcript Release Factor from Drosophila

1996 • 51 citations

Purification of RNA polymerase IIO from calf thymus.

1988 • 50 citations

Regulation of the human general transcription initiation factor TFIIF by phosphorylation.

1994 • 47 citations

Affinity purification of transcription factor IIA from HeLa cell nuclear extracts.

1991 • 43 citations

Structural Changes in the RNA Polymerase II Transcription Complex during Transition from Initiation to Elongation

1998 • 43 citations

Identification and Analysis of a Functional Human Homolog of the SPT4 Gene of Saccharomyces cerevisiae

1996 • 38 citations

Immunoaffinity purification of RNA polymerase II and transcription factors using polyol-responsive monoclonal antibodies

1996 • 30 citations

Different biological activities of the hetero- and homodimers formed by the 47- and 43-kilodalton proteins of transcription factor ATF/E4TF3

1991 • 25 citations

cDNA cloning and characterization of the protein encoded by RD, a gene located in the class III region of the human major histocompatibility complex

1993 • 20 citations

Deleted Work

1955 • 0 citations