Structural Changes in the RNA Polymerase II Transcription Complex during Transition from Initiation to Elongation

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.

1985 • 575 citations

Protein traffic on the heat shock promoter: Parking, stalling, and trucking along

1993 • 507 citations

BASIC MECHANISMS OF TRANSCRIPT ELONGATION AND ITS REGULATION

1997 • 441 citations

The RNA–DNA Hybrid Maintains the Register of Transcription by Preventing Backtracking of RNA Polymerase

1997 • 431 citations

Transcript cleavage factors from E. coli

1993 • 368 citations

Transcriptional arrest: Escherichia coli RNA polymerase translocates backward, leaving the 3′ end of the RNA intact and extruded

1997 • 343 citations

Recycling of the general transcription factors during RNA polymerase II transcription.

1995 • 309 citations

The RNA polymerase II ternary complex cleaves the nascent transcript in a 3'----5' direction in the presence of elongation factor SII.

1992 • 280 citations

The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region.

1992 • 266 citations

RNA Polymerase Switches between Inactivated and Activated States By Translocating Back and Forth along the DNA and the RNA

1997 • 263 citations

Transcription on nucleosomal templates by RNA polymerase II in vitro: inhibition of elongation with enhancement of sequence-specific pausing.

1991 • 239 citations

Factor-stimulated RNA polymerase II transcribes at physiological elongation rates on naked DNA but very poorly on chromatin templates.

1992 • 228 citations

Intrinsic transcript cleavage activity of RNA polymerase.

1995 • 206 citations

A model for the mechanism of polymerase translocation 1 1Edited by A. R. Fersht

1997 • 196 citations

Postinitiation Transcriptional Control in Drosophila melanogaster

1990 • 177 citations

Discontinuous movements of DNA and RNA in RNA polymerase accompany formation of a paused transcription complex

1995 • 161 citations

Structural analysis of ternary complexes of Escherichia coli RNA polymerase

1992 • 154 citations

New models for the mechanism of transcription elongation and its regulation.

1992 • 154 citations

Discontinuous Mechanism of Transcription Elongation

1994 • 145 citations

Promoter Proximal Sequences Modulate RNA Polymerase II Elongation by a Novel Mechanism

1996 • 122 citations

The active site of RNA polymerase II participates in transcript cleavage within arrested ternary complexes.

1994 • 110 citations

RNA Polymerase Slides Home: Pause and Termination Site Recognition

1997 • 109 citations

Identification of a Decay in Transcription Potential That Results in Elongation Factor Dependence of RNA Polymerase II

1995 • 108 citations

The increment of SII-facilitated transcript cleavage varies dramatically between elongation competent and incompetent RNA polymerase II ternary complexes

1993 • 106 citations

The RNA polymerase II elongation complex. Factor-dependent transcription elongation involves nascent RNA cleavage.

1992 • 92 citations

SII-facilitated transcript cleavage in RNA polymerase II complexes stalled early after initiation occurs in primarily dinucleotide increments

1993 • 83 citations

Nascent RNA cleavage by arrested RNA polymerase II does not require upstream translocation of the elongation complex on DNA.

1993 • 80 citations

Short Transcripts of the Ternary Complex Provide Insight into RNA Polymerase II Elongational Pausing

1995 • 73 citations

Increased accommodation of nascent RNA in a product site on RNA polymerase II during arrest.

1996 • 63 citations

Contacts between mammalian RNA polymerase II and the template DNA in a ternary elongation complex

1993 • 49 citations

Translocation and Transcriptional Arrest during Transcript Elongation by RNA Polymerase II

1996 • 44 citations

The Harvey lectures, Series 82

1988 • 12 citations