Promoter-proximal stalling results from the inability to recruit transcription factor IIH to the transcription complex and is a regulated event

DNA EXCISION REPAIR

1996 • 1,127 citations

MECHANISM AND CONTROL OF TRANSCRIPTION INITIATION IN PROKARYOTES

1985 • 1,012 citations

The general transcription factors of RNA polymerase II.

1996 • 1,010 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

The Selectivity of Transcription

1974 • 539 citations

DNA topology and a minimal set of basal factors for transcription by RNA polymerase II

1993 • 374 citations

Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II

1994 • 358 citations

Recycling of the general transcription factors during RNA polymerase II transcription.

1995 • 309 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II

1989 • 304 citations

Transcription mechanisms and regulation

1994 • 299 citations

The RNA polymerase II ternary complex cleaves the nascent transcript in a 3'----5' direction in the presence of elongation factor SII.

1992 • 280 citations

Three Functional Classes of Transcriptional Activation Domains

1996 • 267 citations

Transcriptional elongation by RNA polymerase II is stimulated by transactivators

1994 • 243 citations

The multiple roles of transcription/repair factor TFIIH

1996 • 227 citations

Recruitment of the Putative Transcription-Repair Coupling Factor CSB/ERCC6 to RNA Polymerase II Elongation Complexes

1997 • 191 citations

Requirement for TFIIH kinase activity in transcription by RNA polymerase II

1995 • 189 citations

Three transitions in the RNA polymerase II transcription complex during initiation

1997 • 181 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Transcription factor IIS stimulates elongation of RNA chains.

1987 • 160 citations

The multiple roles of transcription/repair factor TFIIH

1996 • 136 citations

A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes

1997 • 127 citations

Initiation of transcription by RNA polymerase II is limited by melting of the promoter DNA in the region immediately upstream of the initiation site.

1994 • 110 citations

Abortive initiation by RNA polymerase II in vitro at the adenovirus 2 major late promoter.

1987 • 109 citations

The Role of Multisite Phosphorylation in the Regulation of RNA Polymerase II Activity

1994 • 100 citations

The RNA polymerase II elongation complex. Factor-dependent transcription elongation involves nascent RNA cleavage.

1992 • 92 citations

The multifunctional TFIIH complex and transcriptional control

1994 • 88 citations

Purification of human RNA polymerase II and general transcription factors

1996 • 82 citations

A Role for ATP and TFIIH in Activation of the RNA Polymerase II Preinitiation Complex Prior to Transcription Initiation

1996 • 79 citations

Transcription initiation by RNA polymerase II in vitro. At least two nucleotides must be added to form a stable ternary complex.

1987 • 79 citations

Repression of basal transcription by HMG2 is counteracted by TFIIH-associated factors in an ATP-dependent process.

1994 • 64 citations

A heteroduplex template circumvents the energetic requirement for ATP during activated transcription by RNA polymerase II

1994 • 61 citations

Distinct activated and non-activated RNA polymerase II complexes in yeast.

1996 • 61 citations

Promoter Escape by RNA Polymerase II A ROLE FOR AN ATP COFACTOR IN SUPPRESSION OF ARREST BY POLYMERASE AT PROMOTER-PROXIMAL SITES

1996 • 60 citations

Genetic Analysis of the Large Subunit of Yeast Transcription Factor IIE Reveals Two Regions with Distinct Functions

1997 • 58 citations

Elongation by Drosophila RNA polymerase II. Transcription of 3′-extended DNA templates.

1988 • 55 citations

A Three-Step Pathway of Transcription Initiation Leading to Promoter Clearance at an Activated RNA Polymerase II Promoter

1996 • 52 citations

Nucleotide Requirements for Activated RNA Polymerase II Open Complex Formation in Vitro

1995 • 38 citations

Promoter Escape by RNA Polymerase II

1997 • 38 citations

Repression of Basal Transcription by HMG2 Is Counteracted by TFIIH-Associated Factors in an ATP-Dependent Process

1994 • 25 citations

Transcriptional activity of transcription factor IIE is dependent on zinc binding.

1994 • 25 citations

Identification of cis-Acting Elements That Can Obviate a Requirement for the C-terminal Domain of RNA Polymerase II

1995 • 16 citations