A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Signaling Through Scaffold, Anchoring, and Adaptor Proteins

1997 • 2,268 citations

Localization of Protein Kinases by Anchoring Proteins: a Theme in Signal Transduction

1995 • 911 citations

On target with a new mechanism for the regulation of protein phosphorylation

1993 • 901 citations

A Lipid-Anchored Grb2-Binding Protein That Links FGF-Receptor Activation to the Ras/MAPK Signaling Pathway

1997 • 861 citations

Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line.

1987 • 830 citations

Myristylation and palmitylation of Src family members: The fats of the matter

1994 • 694 citations

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

1992 • 688 citations

Studies on the Mechanism of Hormone Action

1972 • 682 citations

Association of Protein Kinase A and Protein Phosphatase 2B with a Common Anchoring Protein

1995 • 615 citations

Coordination of Three Signaling Enzymes by AKAP79, a Mammalian Scaffold Protein

1996 • 557 citations

cAMP-Dependent Regulation of Cardiac L-Type Ca2+ Channels Requires Membrane Targeting of PKA and Phosphorylation of Channel Subunits

1997 • 511 citations

[41] Assay of cyclic AMP-dependent protein kinases

1974 • 498 citations

The MARCKS family of cellular protein kinase C substrates.

1993 • 484 citations

The Marcks brothers: A family of protein kinase C substrates

1992 • 474 citations

Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif

1991 • 437 citations

Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells

1993 • 377 citations

Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons

1994 • 371 citations

S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

1997 • 364 citations

Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain.

1992 • 350 citations

Molecular characterization of the cAMP-dependent protein kinase bound to microtubule-associated protein 2.

1982 • 334 citations

‘Crosstalk’: a pivotal role for protein kinase C in modulating relationships between signal transduction pathways

1991 • 328 citations

Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79.

1992 • 327 citations

The dynamic role of palmitoylation in signal transduction

1995 • 315 citations

Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

1997 • 309 citations

Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.

1995 • 294 citations

A kinase anchor proteins and the intracellular targeting of signals carried by cyclic AMP.

1994 • 291 citations

Protein Kinase A Anchoring

1997 • 272 citations

Molecular Glue: Kinase Anchoring and Scaffold Proteins

1996 • 264 citations

Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein

1997 • 254 citations

Membrane-targeting sequences on AKAP79 bind phosphatidylinositol-4,5-bisphosphate

1998 • 227 citations

More on target with protein phosphorylation: conferring specificity by location.

1996 • 225 citations

Heterogeneous distribution of the cAMP receptor protein RII in the nervous system: evidence for its intracellular accumulation on microtubules, microtubule-organizing centers, and in the area of the Golgi complex.

1986 • 197 citations

Anchoring of protein kinase A facilitates hormone-mediated insulin secretion

1997 • 191 citations

Glucagon-Like Peptide 1(7-36) Amide Stimulates Exocytosis in Human Pancreatic β-Cells by Both Proximal and Distal Regulatory Steps in Stimulus-Secretion Coupling

1998 • 188 citations

Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

1994 • 186 citations

Voltage-dependent potentiation of L-type Ca2+ channels in skeletal muscle cells requires anchored cAMP-dependent protein kinase.

1994 • 185 citations

High affinity binding protein for the regulatory subunit of cAMP-dependent protein kinase II-B

1989 • 184 citations

The phosphorylation of proteins: a major mechanism for biological regulation

1985 • 151 citations

Identification of a 15-kDa cAMP-dependent Protein Kinase-anchoring Protein Associated with Skeletal Muscle L-type Calcium Channels

1997 • 141 citations

Agonist-induced internalization and recycling of the glucagon-like peptide-1 receptor in transfected fibroblasts and in insulinomas

1995 • 136 citations

Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca ²⁺ channel activity by cAMP-dependent protein kinase

1997 • 133 citations

Glucagon-Like Peptide I Increases Cytoplasmic Calcium in Insulin-Secreting βTC3-Cells by Enhancement of Intracellular Calcium Mobilization

1995 • 128 citations

Cloning and characterization of AKAP 95, a nuclear protein that associates with the regulatory subunit of type II cAMP-dependent protein kinase.

1994 • 127 citations

cAMP signaling in neurons: patterns of neuronal expression and intracellular localization for a novel protein, AKAP 150, that anchors the regulatory subunit of cAMP-dependent protein kinase II beta.

1992 • 121 citations

Type II regulatory subunit (RII) of the cAMP-dependent protein kinase interaction with A-kinase anchor proteins requires isoleucines 3 and 5.

1994 • 114 citations

Blotting and band-shifting: techniques for studying protein-protein interactions

1992 • 111 citations

Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors

1997 • 107 citations

Cloning and expression of an intron-less gene for AKAP 75, an anchor protein for the regulatory subunit of cAMP-dependent protein kinase II beta.

1992 • 102 citations

Cloning and Characterization of A-kinase Anchor Protein 100 (AKAP100)

1995 • 97 citations

More on target with protein phosphorylation: conferring specificity by location

1996 • 93 citations

L-Type Calcium Channels in Insulin-Secreting Cells: Biochemical Characterization and Phosphorylation in RINm5F Cells

1997 • 92 citations

Modulation of the Cloned Skeletal Muscle L-Type Ca²⁺Channel by Anchored cAMP-Dependent Protein Kinase

1997 • 90 citations

Mutational Analysis of the A-Kinase Anchoring Protein (AKAP)-binding Site on RII

1996 • 82 citations

Desensitization and phosphorylation of the glucagon-like peptide-1 (GLP-1) receptor by GLP-1 and 4-phorbol 12-myristate 13-acetate.

1996 • 75 citations

The A-kinase Anchoring Domain of Type IIα cAMP-dependent Protein Kinase Is Highly Helical

1997 • 74 citations

Protein Kinase A-dependent Phosphorylation of GLUT2 in Pancreatic β Cells

1996 • 68 citations

Lipid Modifications of Proteins

1992 • 62 citations

Identification of a high affinity binding protein for the regulatory subunit RII beta of cAMP-dependent protein kinase in Golgi enriched membranes of human lymphoblasts.

1992 • 62 citations

Lipid modifications of proteins

1993 • 61 citations

More on target with proteinphosphorylation: conferring specificity by location

1996 • 55 citations

GLP-I(7–36) Amide Augments Ba2+ Current Through L-Type Ca2+ Channel of Rat Pancreatic β-Cell in a cAMP-Dependent Manner

1997 • 52 citations

Activation of KCa channels in airway smooth muscle cells by endogenous protein kinase A

1996 • 46 citations

Desensitization and phosphorylation of the glucagon-like peptide-1 (GLP- 1) receptor by GLP-1 and 4-phorbol 12-myristate 13-acetate

1996 • 45 citations

cAMP-Signaling Pathway Acts in Selective Synergism With Glucose or Tolbutamide to Increase Cytosolic Ca2+ in Rat Pancreatic β-Cells

1996 • 44 citations

Overlay, Ligand Blotting, and Band-Shift Techniques to Study Kinase Anchoring

2003 • 35 citations

Co-localization of the dihydropyridine receptor and the cyclic AMP-binding subunit of an intrinsic protein kinase to the junctional membrane of the transverse tubules of skeletal muscle

1990 • 34 citations

Inhibition of serine/threonine protein phosphatases by secretagogues in insulin-secreting cells.

1995 • 25 citations

Localization of cAMP-dependent protein kinase subunits along the secretory pathway in pancreatic and parotid acinar cells and accumulation of the catalytic subunit in parotid secretory granules following beta-adrenergic stimulation.

1990 • 21 citations

L-Type Calcium Channels in Insulin-Secreting Cells: Biochemical Characterization and Phosphorylation in RINm5F Cells

1997 • 19 citations

Inhibition of serine/threonine protein phosphatases by secretagogues in insulin-secreting cells

1995 • 5 citations

Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein

1997 • 5 citations