Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

Muscarinic activation of ionic currents measured by a new whole-cell recording method.

1988 • 1,777 citations

Okadaic acid: a new probe for the study of cellular regulation

1990 • 1,396 citations

Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function

1993 • 1,302 citations

Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells.

1982 • 1,010 citations

Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion

1987 • 773 citations

Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells

1993 • 377 citations

Calcium and delayed potassium currents in mouse pancreatic beta‐cells under voltage‐clamp conditions.

1986 • 370 citations

Exocytosis elicited by action potentials and voltage‐clamp calcium currents in individual mouse pancreatic B‐cells.

1993 • 272 citations

A novel 145 kd brain cytosolic protein reconstitutes Ca2+-regulated secretion in permeable neuroendocrine cells

1992 • 261 citations

Glucose-induced insulin release depends on functional cooperation between islet cells.

1982 • 231 citations

Protein phosphorylation in electrically permeabilized islets of Langerhans. Effects of Ca2+, cyclic AMP, a phorbol ester and noradrenaline

1988 • 154 citations

Physiology and Pathophysiology of Insulin Secretion

1990 • 137 citations

Insulin; Molecular biology to pathology

1993 • 101 citations

Identification, purification, and characterization of a novel serine/threonine protein phosphatase from bovine brain.

1991 • 90 citations

Effects of protein kinase C activation on the regulation of the stimulus-secretion coupling in pancreatic β-cells

1989 • 84 citations

Effects of okadaic acid, an inhibitor of protein phosphatases-1 and -2A, on glucose transport and metabolism in skeletal muscle

1991 • 61 citations

A key role for a 145-kDa cytosolic protein in the stimulation of Ca(2+)-dependent secretion by protein kinase C.

1992 • 58 citations

The Ionic, Electrical, and Secretory Effects of Protein Kinase C Activation in Mouse Pancreatic B-Cells: Studies with a Phorbol Ester*

1987 • 50 citations

Protein phosphatase inhibitor okadaic acid enhances transmitter release at neuromuscular junctions.

1991 • 45 citations

Action of a phorbol ester on B-cells: potentiation of stimulant-induced electrical activity

1985 • 43 citations

Phosphatases modulate transmission and serotonin facilitation at synapses: Studies with the inhibitor okadaic acid

1991 • 37 citations

Effects of okadaic acid on insulin secretion from rat islets of Langerhans

1993 • 28 citations

Chromostatin inhibits catecholamine secretion in adrenal chromaffin cells by activating a protein phosphatase.

1992 • 25 citations