Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Why genes in pieces?

1978 • 2,256 citations

Plasma Insulin Responses to Oral and Intravenous Glucose: Studies in Normal and Diabetic Subjects*

1967 • 908 citations

Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas.

1987 • 814 citations

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing.

1986 • 686 citations

Hamster preproglucagon contains the sequence of glucagon and two related peptides

1983 • 602 citations

Truncated glucagon‐like peptide I, an insulin‐releasing hormone from the distal gut

1987 • 566 citations

Exon duplication and divergence in the human preproglucagon gene

1983 • 558 citations

Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor.

1980 • 496 citations

Glucagon-Like Peptides GLP-1 and GLP-2, Predicted Products of the Glucagon Gene, Are Secreted Separately from Pig Small Intestine but Not Pancreas*

1986 • 475 citations

Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets

1985 • 303 citations

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability.

1985 • 292 citations

The processing of peptide precursors

1986 • 249 citations

Regulation of immunoreactive-insulin release from a rat cell line (RINm5F)

1983 • 240 citations

Mammalian pancreatic preproglucagon contains three glucagon-related peptides.

1983 • 218 citations

Glucagon gene sequence. Four of six exons encode separate functional domains of rat pre-proglucagon.

1984 • 206 citations

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA.

1985 • 196 citations

Pre-Proglucagon Messenger Ribonucleic Acid: Nucleotide and Encoded Amino Acid Sequences of the Rat Pancreatic Complementary Deoxyribonucleic Acid*

1984 • 147 citations

Anglerfish islet pre-proglucagon II. Nucleotide and corresponding amino acid sequence of the cDNA.

1983 • 137 citations

Human glucagon‐like peptides 1 and 2 activate rat brain adenylate cyclase

1984 • 111 citations

Cell-specific post-translational processing of preproglucagon expressed from a metallothionein-glucagon fusion gene.

1986 • 100 citations

Stimulation of insulin and glucagon secretion by vasoactive intestinal peptide.

1977 • 75 citations

Interaction between prostaglandins and calcium: The importance of bell-shaped dose-response curves

1977 • 71 citations

Molecular forms of glucagon‐like peptides in man

1985 • 64 citations

Glucagon gene transcription in an islet cell line is regulated via a protein kinase C-activated pathway.

1987 • 60 citations

Proglucagon Processing in a Rat Islet Cell Line Resembles Phenotype of Intestine Rather than Pancreas*

1986 • 45 citations

How glucagon-like is glucagon-like peptide-1?

1984 • 41 citations

Noncooperative receptor interactions of glucagon and eleven analogs: inhibition of adenylate cyclase

1983 • 31 citations

Characteristics of the Interaction of the Glucagon Receptor, cAMP, and Insulin Secretion in Parent Cells and Clone 5F of a Cultured Rat Insulinoma

1985 • 17 citations