Macrophage infiltration-associated thymidine phosphorylase expression correlates with increased microvessel density and poor prognosis in astrocytic tumors.

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo

1992 • 2,293 citations

Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma.

1993 • 1,646 citations

Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor

1989 • 726 citations

Microvessel density is a prognostic indicator for patients with astroglial brain tumors

1996 • 490 citations

Thymidine phosphorylase is angiogenic and promotes tumor growth.

1995 • 394 citations

Purification and properties of an endothelial cell growth factor from human platelets.

1987 • 330 citations

Monoclonal Antibody to Single-Stranded DNA Is a Specific and Sensitive Cellular Marker of Apoptosis

1996 • 241 citations

Expression of platelet-derived endothelial cell growth factor in Escherichia coli and confirmation of its thymidine phosphorylase activity

1992 • 209 citations

Regulation of distinct steps of angiogenesis by different angiogenic molecules.

1998 • 208 citations

The effect of a thymidine phosphorylase inhibitor on angiogenesis and apoptosis in tumors.

1999 • 207 citations

Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis

1998 • 207 citations

Vascular endothelial growth factor expression and vascular density as prognostic markers of survival in patients with low-grade astrocytoma

1998 • 204 citations

Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors.

2000 • 187 citations

The activity and expression of thymidine phosphorylase in human solid tumours

1996 • 182 citations

Purification and tissue distribution of human thymidine phosphorylase; high expression in lymphocytes, reticulocytes and tumors

1990 • 180 citations

The influence of oxygen tension and pH on the expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo.

1997 • 179 citations

Platelet-derived endothelial cell growth factor expression correlates with tumour angiogenesis and prognosis in non-small-cell lung cancer

1997 • 140 citations

Kinetic studies of thymidine phosphorylase from mouse liver

1985 • 131 citations

Increased sensitivity to the prodrug 5'-deoxy-5-fluorouridine and modulation of 5-fluoro-2'-deoxyuridine sensitivity in MCF-7 cells transfected with thymidine phosphorylase

1995 • 130 citations

Prognostic role of thymidylate synthase, thymidine phosphorylase/platelet-derived endothelial cell growth factor, and proliferation markers in colorectal cancer.

2000 • 127 citations

Growth factor-mediated angiogenesis in the malignant progression of glial tumors: A review

1998 • 122 citations

Prevention of Hypoxia-Induced Apoptosis by the Angiogenic Factor Thymidine Phosphorylase

1998 • 112 citations

Thymidine Phosphorylase Mediates the Sensitivity of Human Colon Carcinoma Cells to 5-Fluorouracil

1995 • 106 citations

Significance of platelet-derived endothelial cell growth factor in the angiogenesis of human gastric cancer.

1998 • 87 citations

Thymidine phosphorylase expression is associated with both increase of intratumoral microvessels and decrease of apoptosis in human colorectal carcinomas.

1999 • 86 citations

Thymidine phosphorylase activity of platelet‐derived endothelial cell growth factor is responsible for endothelial cell mitogenicity

1993 • 76 citations

Neurotrophic action of gliostatin on cortical neurons. Identity of gliostatin and platelet-derived endothelial cell growth factor.

1992 • 71 citations

Prognostic Value of Vascular Endothelial Growth Factor and its Receptors Flt-1 and Flk-1 in Astrocytic Tumours

2001 • 70 citations

Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in macrophages correlates with tumor angiogenesis and prognosis in invasive breast cancer.

1998 • 50 citations

A Novel Glial Growth Inhibitory Factor, Gliostatin, Derived from Neurofibroma

1992 • 49 citations

Human platelet‐derived endothelial cell growth factor is homologous to Escherichia coli thymidine phosphorylase

1992 • 44 citations

Expression of thymidine phosphorylase as an indicator of poor prognosis for patients with transitional cell carcinoma of the bladder

2000 • 38 citations

Regulation of expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor in human colon carcinoma cells.

1998 • 33 citations

The value of platelet-derived endothelial cell growth factor as a novel predictor of advancement of uterine cervical cancers.

2000 • 29 citations

Neurotrophic action of gliostatin on cocultured neurons with glial cells

1993 • 24 citations

Thymidine phosphorylase expression results in a decrease in apoptosis and increase in intratumoral microvessel density in human gastric carcinomas

2000 • 23 citations

Stromal angiogenesis in human glioma: A role of platelet-derived endothelial cell growth factor

1998 • 19 citations

Expression of Thymidine Phosphorylase in Epithelial Ovarian Cancer: Correlation with Angiogenesis, Apoptosis, and Ultrasound-Derived Peak Systolic Velocity

2000 • 17 citations

Development and Characterization of 1C6–203, a New Monoclonal Antibody Specific to Human Thymidine Phosphorylase

2001 • 15 citations

Expression of the angiogenic factor thymidine phosphorylase in human astrocytic tumors

2000 • 15 citations