Thymidine phosphorylase activity of platelet‐derived endothelial cell growth factor is responsible for endothelial cell mitogenicity

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

ADENOSINE-DEAMINASE DEFICIENCY IN TWO PATIENTS WITH SEVERELY IMPAIRED CELLULAR IMMUNITY

1972 • 1,654 citations

Transformation of yeast by a replicating hybrid plasmid

1978 • 1,362 citations

Laboratory course manual for methods in yeast genetics

1986 • 1,310 citations

Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor

1989 • 726 citations

Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)

1977 • 416 citations

Purification and properties of an endothelial cell growth factor from human platelets.

1987 • 330 citations

The yeast ubiquitin gene: head-to-tail repeats encoding a polyubiquitin precursor protein

1984 • 313 citations

Permeation of Nucleosides, Nucleic Acid Bases, and Nucleotides in Animal Cells

1980 • 312 citations

Determination of the number of endothelial cells in culture using an acid phosphatase assay

1986 • 206 citations

Platelet-derived endothelial cell growth factor has thymidine phosphorylase activity

1992 • 198 citations

Purification and tissue distribution of human thymidine phosphorylase; high expression in lymphocytes, reticulocytes and tumors

1990 • 180 citations

Genetic and biochemical consequences of thymidylate stress

1982 • 101 citations

Catabolism of thymidine in human blood platelets purification and properties of thymidine phosphorylase

1981 • 100 citations

Increasing gene expression in yeast by fusion to ubiquitin

1989 • 95 citations

The genetic consequences of nucleotide precursor pool imbalance in mammalian cells

1984 • 94 citations

Extracellular purine nucleosides stimulate cell division and morphogenesis: Pathological and physiological implications

1992 • 88 citations

Role of thymidine in biochemical modulation: a review.

1987 • 79 citations

Characterization and partial purification of an endothelial cell growth factor from human platelets.

1984 • 78 citations

Saccharomyces Cerevisiae Strains that Overexpress Heterologous Proteins

1991 • 68 citations

Production of platelet-derived endothelial cell growth factor by normal and transformed human cells in culture.

1989 • 60 citations

High-yield purification of platelet-derived endothelial cell growth factor: structural characterization and establishment of a specific antiserum

1989 • 53 citations

High-Level Expression and In Vivo Processing of Chimeric Ubiquitin Fusion Proteins in Saccharomyces Cerevisiae

1989 • 53 citations

Metabolic breakdown of [3H]thymidine and the inability to measure human lymphocyte proliferation by incorporation of radioactivity.

1986 • 52 citations

Platelet-derived endothelial cell growth factor

1991 • 51 citations

Genetic Consequences of Nucleotide Pool Imbalance

1985 • 45 citations

Human platelet‐derived endothelial cell growth factor is homologous to Escherichia coli thymidine phosphorylase

1992 • 44 citations

Localization of platelet-derived endothelial cell growth factor in human placenta and purification of an alternatively processed form.

1990 • 44 citations

Cross-linked collagen surface for cell culture that is stable, uniform, and optically superior to conventional surfaces

1985 • 38 citations

Purification and characterization of uridine and thymidine phosphorylase from Lactobacillus casei

1990 • 37 citations

The effects of intact platelets on cultured human endothelial cells

1977 • 36 citations

A platelet factor stimulating the proliferation of vascular endothelial cells

1985 • 32 citations

Covalent linkage between nucleotides and platelet-derived endothelial cell growth factor.

1991 • 30 citations

The enzymic conversion of D-glucuronate to L-ascorbate and L-xylulose in animal tissues

1958 • 28 citations

The human blood platelet: A cellular model to study the degradation of thymidine and its inhibition

1982 • 27 citations

The role of blood platelets in nucleoside metabolism: assay, cellular location and significance of thymidine phosphorylase in human blood

1988 • 27 citations

Sterically hindered aromatic compounds. XI. Spectral and product studies of the decomposition of N-nitrosoacetanilides

1982 • 27 citations

Purification of a ubiquitin protein peptidase from yeast with efficient in vitro assays

1989 • 26 citations

Purification of thymidine phosphorylase from human amniochorion

1978 • 24 citations

Platelet-derived Endothelial Cell Growth Factor: Structure and function.

1991 • 19 citations

Partial purification of a thymidine phosphorylase from human gastric cancer.

1986 • 17 citations

The role of blood platelets in nucleoside metabolism: regulation of platelet thymidine phosphorylase

1988 • 15 citations

Expression of recombinant platelet‐derived endothelial cell growth factor in the yeast Saccharomyces cerevisiae

1992 • 7 citations

Genetic and Biochemical Effects of Thymidylate Stress in Yeast

1985 • 6 citations