Thymidine phosphorylase is angiogenic and promotes tumor growth.

Some new, simple and efficient stereological methods and their use in pathological research and diagnosis

1988 • 2,948 citations

Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor

1989 • 726 citations

A general method for rapid site-directed mutagenesis using the polymerase chain reaction

1990 • 642 citations

The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor.

1976 • 357 citations

Relationship of endothelial cell proliferation to tumor vascularity in human breast cancer.

1993 • 209 citations

Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5?-deoxy-5-fluorouridine

1993 • 209 citations

Expression of platelet-derived endothelial cell growth factor in Escherichia coli and confirmation of its thymidine phosphorylase activity

1992 • 209 citations

Platelet-derived endothelial cell growth factor has thymidine phosphorylase activity

1992 • 198 citations

Purification and tissue distribution of human thymidine phosphorylase; high expression in lymphocytes, reticulocytes and tumors

1990 • 180 citations

Inhibition of vascular endothelial cell growth by activin-A.

1993 • 157 citations

Association of ovarian Malignancy With Expression of Paltelet-Derived Endothelial Cell Growth Factor

1994 • 139 citations

Deoxyribosyl Transfer

1964 • 139 citations

Stimulation of angiogenesis by adenosine on the chick chorioallantoic membrane.

1986 • 116 citations

Topoisomerase II alpha co-amplification with erbB2 in human primary breast cancer and breast cancer cell lines: relationship to m-AMSA and mitoxantrone sensitivity.

1993 • 115 citations

Sampling schemes for estimating nerve fibre size. I. Methods for nerve trunks of mixed fascicularity.

1984 • 114 citations

Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution.

1990 • 90 citations

Identification and Comparative Analysis of Thymidine Phosphorylase in the Plasma of Healthy Subjects and Cancer Patients: Brief Communication 2

1977 • 81 citations

Thymidine phosphorylase activity of platelet‐derived endothelial cell growth factor is responsible for endothelial cell mitogenicity

1993 • 76 citations

Human platelet‐derived endothelial cell growth factor is homologous to Escherichia coli thymidine phosphorylase

1992 • 44 citations

Elevated Thymidine Phosphorylase Activity in the Plasma and Ascitic Fluids of Tumor-Bearing Animals

1978 • 28 citations

The human blood platelet: A cellular model to study the degradation of thymidine and its inhibition

1982 • 27 citations

cDNA transfection followed by the isolation of a MCF-7 breast cell line resistant to tamoxifen in vitro and in vivo

1993 • 14 citations