High-frequency developmental abnormalities in p53-deficient mice

p53 Mutations in Human Cancers

1991 • 8,133 citations

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1992 • 4,648 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

1993 • 2,911 citations

A Text-Book of Oral Pathology

1950 • 2,435 citations

Thymocyte apoptosis induced by p53-dependent and independent pathways

1993 • 2,322 citations

Tumor spectrum analysis in p53-mutant mice

1994 • 2,034 citations

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

1992 • 1,877 citations

The Atlas of Mouse Development

1992 • 1,782 citations

The atlas of mouse development

1993 • 1,427 citations

A textbook of oral pathology

1984 • 1,255 citations

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

1994 • 671 citations

The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice.

1994 • 564 citations

Growth factor modulation of p53-mediated growth arrest versus apoptosis.

1995 • 377 citations

Enhanced proliferative potential in culture of cells from p53-deficient mice.

1993 • 341 citations

The embryonic development of mammalian neural tube defects

1990 • 337 citations

Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents

1993 • 305 citations

Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene.

1994 • 295 citations

p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation.

1994 • 264 citations

Mice with reduced levels of p53 protein exhibit the testicular giant-cell degenerative syndrome.

1993 • 179 citations

Expression of p53 protein in spermatogenesis is confined to the tetraploid pachytene primary spermatocytes.

1993 • 141 citations

Dose-incidence Relationships for Exencephalia, Anophthalmia and Prenatal Mortality in Mouse Embryos Irradiated with Fission Neutrons or 250 kV X-rays

1987 • 26 citations

Precise sex selected births of mice following single cell embryo biopsy and Y-linked testis-specific gene analysis*

1993 • 17 citations