Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

Innate Immune Recognition

2002 • 8,157 citations

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

1998 • 2,615 citations

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1998 • 2,373 citations

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

1998 • 2,106 citations

Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

1998 • 1,890 citations

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

2003 • 1,623 citations

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

1994 • 1,161 citations

Pattern Recognition Receptors

2002 • 1,139 citations

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

1991 • 695 citations

The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses

1998 • 666 citations

A Role for CD40 Expression on CD8 ⁺ T Cells in the Generation of CD8 ⁺ T Cell Memory

2002 • 629 citations

Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells

2002 • 584 citations

Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells.

1996 • 515 citations

Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice

1994 • 321 citations

Priming of Memory But Not Effector CD8 T Cells by a Killed Bacterial Vaccine

2001 • 294 citations

CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge

1996 • 287 citations

Compromised Influenza Virus-Specific CD8⁺-T-Cell Memory in CD4⁺-T-Cell-Deficient Mice

2002 • 286 citations

Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on listeria monocytogenes infection

1995 • 244 citations

Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on Listeria monocytogenes infection.

1994 • 201 citations

Immunity to Listeria infection

2000 • 153 citations

Diminished Primary and Secondary Influenza Virus-Specific CD8⁺T-Cell Responses in CD4-Depleted Ig^−/−Mice

2000 • 142 citations

CD8 lethargy in the absence of CD4 help

2002 • 137 citations

Cutting Edge: Paradigm Revisited: Antibody Provides Resistance toListeriaInfection

1999 • 136 citations

Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells

1998 • 129 citations

A Specific Role for B Cells in the Generation of CD8 T Cell Memory by RecombinantListeria monocytogenes

2003 • 114 citations

Reduced Functional Capacity of CD8+ T Cells Expanded by Post-Exposure Vaccination of γ-Herpesvirus-Infected CD4-Deficient Mice

2002 • 40 citations