RBP1 Recruits the mSIN3-Histone Deacetylase Complex to the Pocket of Retinoblastoma Tumor Suppressor Family Proteins Found in Limited Discrete Regions of the Nucleus at Growth Arrest

The regulation of E2F by pRB-family proteins

1998 • 2,297 citations

A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

1996 • 1,769 citations

Retinoblastoma protein recruits histone deacetylase to repress transcription

1998 • 1,231 citations

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

1999 • 1,068 citations

Rb Interacts with Histone Deacetylase to Repress Transcription

1998 • 965 citations

NURD, a Novel Complex with Both ATP-Dependent Chromatin-Remodeling and Histone Deacetylase Activities

1998 • 946 citations

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1998 • 919 citations

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

1999 • 898 citations

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

1999 • 806 citations

The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities

1998 • 791 citations

ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

1999 • 705 citations

Retinoblastoma protein switches the E2F site from positive to negative element

1992 • 663 citations

Regulation of E2F1 activity by acetylation

2000 • 654 citations

Regulation of the cyclin E gene by transcription factor E2F1.

1995 • 634 citations

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

1994 • 625 citations

HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

1996 • 623 citations

Histone acetylases and deacetylases in cell proliferation

1999 • 598 citations

Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex

1997 • 565 citations

Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters

1997 • 546 citations

Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

1996 • 541 citations

Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

1991 • 541 citations

HDAC4 deacetylase associates with and represses the MEF2 transcription factor

1999 • 539 citations

Toward an understanding of the functional complexity of the E2F and retinoblastoma families.

1998 • 524 citations

Mechanism of active transcriptional repression by the retinoblastoma protein

1995 • 494 citations

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.

1994 • 493 citations

Regulation of cell proliferation by the E2F transcription factors

1998 • 486 citations

Fundamentally Different Logic of Gene Regulation in Eukaryotes and Prokaryotes

1999 • 472 citations

Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein

1991 • 464 citations

Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein.

1993 • 460 citations

Isolation and Characterization of cDNAs Corresponding to an Additional Member of the Human Histone Deacetylase Gene Family

1997 • 431 citations

A multiple subunit Mi-2 histone deacetylase from Xenopus laevis cofractionates with an associated Snf2 superfamily ATPase

1998 • 426 citations

Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression

2000 • 409 citations

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

1993 • 402 citations

Cell cycle regulation of the human cdc2 gene.

1992 • 396 citations

A role for histone deacetylase activity in HDAC1-mediated transcriptional repression

1998 • 363 citations

Active Transcriptional Repression by the Rb–E2F Complex Mediates G1 Arrest Triggered by p16INK4a, TGFβ, and Contact Inhibition

1999 • 355 citations

E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.

1993 • 353 citations

Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway

2000 • 317 citations

Nuclear organization of DNA replication in primary mammalian cells

2000 • 298 citations

RB and hbrm cooperate to repress the activation functions of E2F1

1997 • 293 citations

Characterization of a human RPD3 ortholog, HDAC3

1998 • 292 citations

SAP30, a Novel Protein Conserved between Human and Yeast, Is a Component of a Histone Deacetylase Complex

1998 • 288 citations

HDAC4, a Human Histone Deacetylase Related to Yeast HDA1, Is a Transcriptional Corepressor

1999 • 280 citations

Histone deacetylases: transcriptional repression with SINers and NuRDs

1999 • 274 citations

A retinoblastoma-binding protein related to a negative regulator of Ras in yeast

1993 • 265 citations

Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein.

1994 • 253 citations

The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

1998 • 253 citations

Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene.

1992 • 250 citations

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.

1995 • 248 citations

SAP30, a Component of the mSin3 Corepressor Complex Involved in N-CoR-Mediated Repression by Specific Transcription Factors

1998 • 212 citations

Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F.

1993 • 196 citations

HDA1 and HDA3 Are Components of a Yeast Histone Deacetylase (HDA) Complex

1996 • 189 citations

Direct Transcriptional Repression by pRB and Its Reversal by Specific Cyclins

1995 • 179 citations

RBP1 Recruits Both Histone Deacetylase-Dependent and -Independent Repression Activities to Retinoblastoma Family Proteins

1999 • 171 citations

Role of the LXCXE Binding Site in Rb Function

2000 • 162 citations

Inhibition of E2F-1 Transactivation by Direct Binding of the Retinoblastoma Protein

1993 • 151 citations

Retinoblastoma protein meets chromatin

1999 • 143 citations

Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes.

1993 • 141 citations

Regions of the Retinoblastoma Gene Product Required for its Interaction with the E2F Transcription Factor are Necessary for E2 Promoter Repression and pRb-Mediated Growth Suppression

1993 • 140 citations

Mechanism of Transcriptional Repression of E2F by the Retinoblastoma Tumor Suppressor Protein

1999 • 128 citations

The Retinoblastoma Susceptibility Gene Product Represses Transcription When Directly Bound to the Promoter

1995 • 115 citations

Identification of distinct roles for separate E1A domains in disruption of E2F complexes.

1993 • 113 citations

A General Requirement for the Sin3-Rpd3 Histone Deacetylase Complex in Regulating Silencing in Saccharomyces cerevisiae

1999 • 112 citations

Mutagenesis of the pRB Pocket Reveals that Cell Cycle Arrest Functions Are Separable from Binding to Viral Oncoproteins

2000 • 112 citations

Differential Display Cloning of a Novel Human Histone Deacetylase (HDAC3) cDNA from PHA-Activated Immune Cells

1998 • 110 citations

Global Transcription Regulators of Eukaryotes

1999 • 106 citations

Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes

1997 • 104 citations

Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression.

1993 • 88 citations

Viral Ski Inhibits Retinoblastoma Protein (Rb)-mediated Transcriptional Repression in a Dominant Negative Fashion

1999 • 87 citations

Establishment of Irreversible Growth Arrest in Myogenic Differentiation Requires the RB LXCXE-Binding Function

2000 • 72 citations

RBP1 induces growth arrest by repression of E2F-dependent transcription

1999 • 71 citations

E2F: a nodal point in cell cycle regulation

1997 • 48 citations

Independent Regions of Adenovirus E1A are Required for Binding to and Dissociation of E2F-Protein Complexes

1993 • 47 citations

E2F Is Required To Prevent Inappropriate S-Phase Entry of Mammalian Cells

2000 • 41 citations

Characterization of an E2F-p130 complex formed during growth arrest

1997 • 27 citations

Alternative splicing of the RBP1 gene clusters in an internal exon that encodes potential phosphorylation sites.

1993 • 13 citations

Oncogenes: Present status

1993 • 7 citations