The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

1996 • 1,769 citations

Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

1996 • 1,567 citations

E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins

1992 • 1,552 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Retinoblastoma protein recruits histone deacetylase to repress transcription

1998 • 1,231 citations

Rb Interacts with Histone Deacetylase to Repress Transcription

1998 • 965 citations

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1998 • 919 citations

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G₁/S-Regulatory Genes

1995 • 910 citations

What's Up and Down with Histone Deacetylation and Transcription?

1997 • 831 citations

Retinoblastoma protein switches the E2F site from positive to negative element

1992 • 663 citations

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.

1993 • 531 citations

Identification of a growth suppression domain within the retinoblastoma gene product.

1992 • 413 citations

Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs

1997 • 363 citations

Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

1995 • 361 citations

An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription.

1993 • 342 citations

Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members.

1995 • 299 citations

Histone Deacetylase: A Regulator of Transcription

1996 • 298 citations

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes.

1995 • 254 citations

The restriction point and control of cell proliferation

1997 • 253 citations

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.

1995 • 248 citations

E2F and Cell Proliferation: A World Turned Upside Down

1996 • 234 citations

DP and E2F proteins: coordinating transcription with cell cycle progression

1994 • 205 citations

Retinoblastoma protein family in cell cycle and cancer: A review

1996 • 198 citations

The Transcription Factor E2F-1 Is a Downstream Target of RB Action

1995 • 190 citations

Activity of the Retinoblastoma Family Proteins, pRB, p107, and p130, during Cellular Proliferation and Differentiation

1996 • 138 citations

Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma

1997 • 129 citations

The CBP co-activator stimulates E2F1/DP1 activity

1996 • 117 citations

The Retinoblastoma Susceptibility Gene Product Represses Transcription When Directly Bound to the Promoter

1995 • 115 citations

Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases.

1996 • 110 citations

The World Wide Web as an Instructional Tool

1996 • 100 citations

Physical Interaction between the Mitogen-responsive Serum Response Factor and Myogenic Basic-Helix-Loop-Helix Proteins

1996 • 100 citations

Domains A and B in the Rb Pocket Interact To Form a Transcriptional Repressor Motif

1996 • 98 citations

E2F and the molecular mechanisms of early cell-cycle control

1996 • 71 citations

The Rb Family Contains a Conserved Cyclin-Dependent-Kinase-Regulated Transcriptional Repressor Motif

1996 • 67 citations

Transcriptional Repression and Growth Suppression by the p107 Pocket Protein

1996 • 54 citations

Adenovirus E1A activates cyclin A gene transcription in the absence of growth factors through interaction with p107

1996 • 35 citations

The Serum Unresponsive Rous Sarcoma Virus Promoter Sustains a High Serum Response Factor-Dependent Transcription in Vitro

1993 • 6 citations