Back to search

hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci

Data up to Jan 2025

Published2001
Citations248
References65

Total Citations Per Year

Abstract

References (65)

MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY

1996 • 1,485 citations

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21 WAF1

1997 • 895 citations

PCNA: structure, functions and interactions

1997 • 886 citations

MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR

1991 • 876 citations

Eukaryotic DNA mismatch repair

1999 • 860 citations

Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA

1996 • 790 citations

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1995 • 599 citations

Dynamics of DNA Replication Factories in Living Cells

2000 • 572 citations

Requirement for PCNA in DNA Mismatch Repair at a Step Preceding DNA Resynthesis

1996 • 569 citations

GTBP, a 160-Kilodalton Protein Essential for Mismatch-binding Activity in Human Cells

1995 • 528 citations

Visualization of replication factories attached to a nucleoskeleton

1993 • 472 citations

Mutations of GTBP in Genetically Unstable Cells

1995 • 471 citations

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.

1990 • 408 citations

Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα

1998 • 405 citations

PCNA binding through a conserved motif

1998 • 383 citations

Identification and characterization of Saccharomyces cerevisiae EXO1 , a gene encoding an exonuclease that interacts with MSH2

1997 • 382 citations

Building a Replisome from Interacting Pieces

1999 • 368 citations

hMSH2–hMSH6 Forms a Hydrolysis-Independent Sliding Clamp on Mismatched DNA

1999 • 368 citations

hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA

1996 • 363 citations

Heteroduplex repair in extracts of human HeLa cells

1991 • 355 citations

Mispair specificity of methyl-directed DNA mismatch correction in vitro.

1988 • 341 citations

Post-replicative base excision repair in replication foci

1999 • 337 citations

MutS mediates heteroduplex loop formation by a translocation mechanism

1997 • 325 citations

Mismatch repair: mechanisms and relationship to cancer susceptibility

1995 • 307 citations

Methyl-directed DNA Mismatch Correction

1989 • 297 citations

Mismatch repair defects in cancer

2000 • 292 citations

A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

1995 • 276 citations

The Werner Syndrome Gene Product Co-purifies with the DNA Replication Complex and Interacts with PCNA and Topoisomerase I

1999 • 249 citations

Proliferating cell nuclear antigen: More than a clamp for DNA polymerases

1997 • 248 citations

An interaction between DNA ligase I and proliferating cell nuclear antigen: Implications for Okazaki fragment synthesis and joining

1997 • 242 citations

The DNA Repair Endonuclease XPG Binds to Proliferating Cell Nuclear Antigen (PCNA) and Shares Sequence Elements with the PCNA-binding Regions of FEN-1 and Cyclin-dependent Kinase Inhibitor p21

1997 • 236 citations

DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro

1997 • 227 citations

Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction

1993 • 224 citations

Functional Interaction of Proliferating Cell Nuclear Antigen with MSH2-MSH6 and MSH2-MSH3 Complexes

2000 • 223 citations

ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair

1998 • 218 citations

Repair of DNA heteroduplexes containing small heterologous sequences in Escherichia coli.

1992 • 215 citations

Mismatch repair deficiency associated with overexpression of the MSH3 gene

1998 • 210 citations

DNA ligaseI is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories

1998 • 206 citations

The great GATC: DNA methylation in E. coli

1989 • 203 citations

A Role for Exonuclease I from S. pombe in Mutation Avoidance and Mismatch Correction

1995 • 202 citations

Evidence for Involvement of Yeast Proliferating Cell Nuclear Antigen in DNA Mismatch Repair

1996 • 200 citations

Nucleotide-promoted Release of hMutSα from Heteroduplex DNA Is Consistent with an ATP-dependent Translocation Mechanism

1998 • 190 citations

Identification of hMutLβ, a Heterodimer of hMLH1 and hPMS1

1999 • 183 citations

hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha

1998 • 173 citations

Replication factories and nuclear bodies: the ultrastructural characterization of replication sites during the cell cycle

1994 • 168 citations

Mechanism Whereby Proliferating Cell Nuclear Antigen Stimulates Flap Endonuclease 1

2000 • 163 citations

Mutations in Yeast Proliferating Cell Nuclear Antigen Define Distinct Sites for Interaction with DNA Polymerase δ and DNA Polymerase ε

1997 • 162 citations

Two modes of FEN1 binding to PCNA regulated by DNA

2000 • 160 citations

Homologous regions of Fen1 and p21Cip1 compete for binding to the same site on PCNA: a potential mechanism to co-ordinate DNA replication and repair

1997 • 155 citations

Mismatch-, MutS-, MutL-, and Helicase II-dependent Unwinding from the Single-strand Break of an Incised Heteroduplex

1998 • 149 citations

The Evolutionarily Conserved Zinc Finger Motif in the Largest Subunit of Human Replication Protein A Is Required for DNA Replication and Mismatch Repair but Not for Nucleotide Excision Repair

1998 • 146 citations

Identification of base mismatches recognized by the heteroduplex-DNA-repair system of Streptococcus pneumoniae

1982 • 141 citations

Dominant negative mutator mutations in the mutS gene of Escherichia coli

1994 • 127 citations

p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex.

1996 • 121 citations

Sliding clamps: A (tail)ored fit

2000 • 116 citations

Reversible Phosphorylation at the C-terminal Regulatory Domain of p21Waf1/Cip1 Modulates Proliferating Cell Nuclear Antigen Binding

2000 • 104 citations

The C-terminal Region of p21 Is Involved in Proliferating Cell Nuclear Antigen Binding but Does Not Appear to Be Required for Growth Inhibition

1995 • 91 citations

Mismatch-containing oligonucleotide duplexes bound by theE.coli mutS-encoded protein

1988 • 90 citations

Saccharomyces cerevisiaeMsh2p and Msh6p ATPase Activities Are Both Required during Mismatch Repair

1998 • 90 citations

Direct Interaction of Proliferating Cell Nuclear Antigen with the p125 Catalytic Subunit of Mammalian DNA Polymerase δ

1999 • 88 citations

Mutation in the Magnesium Binding Site of hMSH6 Disables the hMutSα Sliding Clamp from Translocating along DNA

2000 • 85 citations

Mediating mismatch repair

2000 • 73 citations

Essential interaction between the fission yeast DNA polymerase δ subunit Cdc27 and Pcn1 (PCNA) mediated through a C-terminal p21Cip1-like PCNA binding motif

2000 • 66 citations

Effect of hMSH6 cDNA expression on the phenotype of mismatch repair-deficient colon cancer cell line HCT15

1999 • 37 citations

Molecular Cloning of the N-Terminus of GTBP

1996 • 34 citations

Cited By (0)

Loading...
hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci (2001) – Genes & Development | Metascience Observatory Explorer