Dominant negative mutator mutations in the mutS gene of Escherichia coli

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

1992 • 4,683 citations

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

1978 • 4,472 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

MUTANTS OF ESCHERICHIA COLI REQUIRING METHIONINE OR VITAMIN B ₁₂

1950 • 2,926 citations

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1993 • 2,282 citations

MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR

1991 • 876 citations

The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants

1989 • 728 citations

A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions.

1989 • 451 citations

[7] Uses of transposons with emphasis on Tn10

1991 • 412 citations

Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction.

1980 • 391 citations

Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions.

1992 • 353 citations

Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs.

1986 • 353 citations

EFFECTS OF HIGH LEVELS OF DNA ADENINE METHYLATION ON METHYL-DIRECTED MISMATCH REPAIR IN ESCHERICHIA COLI

1983 • 294 citations

Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins.

1992 • 221 citations

Repair of DNA heteroduplexes containing small heterologous sequences in Escherichia coli.

1992 • 215 citations

Mismatch correction at O6-methylguanine residues in E. coli DNA

1982 • 215 citations

Pleiotropic effects of a DNA adenine methylation mutation (dam-3) in Escherichia coli K12

1975 • 183 citations

Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase and mismatch binding activities.

1991 • 164 citations

Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene

1989 • 148 citations

The yeast gene MSH3 defines a new class of eukaryotic MutS homologues

1993 • 140 citations

Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene.

1989 • 128 citations

Bromouracil mutagenesis and mismatch repair in mutator strains of Escherichia coli

1978 • 121 citations

Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12

1989 • 101 citations

HYPER-RECOMBINING RECIPIENT STRAINS IN BACTERIAL CONJUGATION

1986 • 98 citations

Isolation and characterization of dam+ revertants and suppressor mutations that modify secondary phenotypes of dam-3 strains of Escherichia coli K-12

1980 • 85 citations

MISMATCH REPAIR MUTATIONS OF ESCHERICHIA COLI K12 ENHANCE TRANSPOSON EXCISION

1985 • 83 citations

Nucleotide sequence of the Salmonella typhimurium mutS gene required for mismatch repair: homology of MutS and HexA of Streptococcus pneumoniae

1988 • 83 citations

Nucleotide sequence of the hexA gene for DNA mismatch repair in Streptococcus pneumoniae and homology of hexA to mutS of Escherichia coli and Salmonella typhimurium

1988 • 75 citations

Frameshift mutagenesis of lambda prophage by 9-aminoacridine, proflavin and ICR-191

1984 • 73 citations

Mutator Gene of Escherichia coli B

1967 • 73 citations

A simple and rapid method to obtain substitution mutations in Escherichia coli: isolation of a dam deletion/insertion mutation

1988 • 65 citations

Marker-specific effects in genetic recombination

1970 • 61 citations

Mutator mutations in Escherichia coli induced by the insertionof phage Mu and the transposable resistance elements Tn5 and Tn10

1982 • 59 citations

Methyl-Directed Repair of DNA Mismatches

1988 • 47 citations

Mismatch repair genes of Streptococcus pneumoniae: HexA confers a mutator phenotype in Escherichia coli by negative complementation

1991 • 44 citations

Mutagenesis, by methylating and ethylating agents, in mutH, mutL, mutS, and uvrD mutants of Salmonella typhimurium LT2

1983 • 44 citations

Mutation spectrum inEscherichia coliDNA mismatch repair deficient (mutH) strain

1987 • 44 citations

Analysis of the genetic requirements for viability of Escherichia coli K-12 DNA adenine methylase (dam) mutants

1993 • 29 citations

Nucleotide sequence of theEscherichia coli mutHgene

1987 • 24 citations

The Escherichia coli fdv gene probably encodes mutS and is located at minute 58.8 adjacent to the hyc-hyp gene cluster

1991 • 19 citations

Azotobacter vinelandii mutS: nucleotide sequence and mutant analysis

1993 • 13 citations