Replication factories and nuclear bodies: the ultrastructural characterization of replication sites during the cell cycle

Dynamics of three-dimensional replication patterns during the s-phase, analysed by double labelling of dna and confocal microscopy

1992 • 721 citations

Mapping replicational sites in the eucaryotic cell nucleus.

1989 • 520 citations

Dynamic organization of DNA replication in mammalian cell nuclei: spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences.

1992 • 478 citations

Visualization of replication factories attached to a nucleoskeleton

1993 • 472 citations

Structural organizations of replicon domains during DNA synthetic phase in the mammalian nucleus

1986 • 436 citations

The nonchromatin substructures of the nucleus: the ribonucleoprotein (RNP)-containing and RNP-depleted matrices analyzed by sequential fractionation and resinless section electron microscopy.

1986 • 420 citations

Identification of a novel nuclear domain.

1991 • 285 citations

Replication occurs at a nucleoskeleton.

1986 • 230 citations

Visualization of a filamentous nucleoskeleton with a 23 nm axial repeat.

1988 • 216 citations

The nucleoskeleton and the topology of replication

1991 • 205 citations

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro

1989 • 192 citations

The coiled body

1993 • 181 citations

Nuclear bodies (NBs): A newly “rediscovered” organelle

1992 • 178 citations

Spatial and temporal distribution of DNA replication sites localized by immunofluorescence and confocal microscopy in mouse fibroblasts

1991 • 170 citations

The cytoplasmic filament system in critical point-dried whole mounts and plastic-embedded sections.

1985 • 160 citations

A gentle method for preparing cyto- and nucleo-skeletons and associated chromatin

1988 • 155 citations

The nucleoskeleton: Artefact, passive framework or active site?

1988 • 143 citations

Chapter 4 Poration by α-Toxin and Streptolysin O: An Approach to Analyze Intracellular Processes

1989 • 126 citations

Localization of Nuclear Functions as Revealed by Ultrastructural Autoradiography and Cytochemistry

1974 • 119 citations

The timing of the formation and usage of replicase clusters in s-phase nuclei of human diploid fibroblasts

1991 • 101 citations

Replication and transcription sites are colocalized in human cells

1994 • 96 citations

Assigning functions to nucleolar structures

1991 • 79 citations

High-resolution detection of newly synthesized DNA by anti-bromodeoxyuridine antibodies identifies specific chromatin domains.

1990 • 76 citations

Visualization of replication sites in unfixed human cells

1993 • 66 citations

A cell-cycle-dependent DNA polymerase activity that replicates intact DNA in chromatin

1986 • 66 citations

Compartmentalization within the nucleus: discovery of a novel subnuclear region.

1991 • 64 citations

Attachment of DNA to the nucleoskeleton of HeLa cells examined using physiological conditions

1990 • 58 citations

Hypothesis: RNA polymerase: Structural determinat of the chromatin loop and the chromosome

1994 • 58 citations

Transcriptionally active minichromosomes are attached transiently in nuclei through transcription units

1993 • 40 citations

Temperature-dependent association of DNA polymerase α activity with the nuclear matrix

1990 • 24 citations

Eukaryotic DNA replication is a topographically ordered process

1992 • 22 citations

Does transcription by RNA polymerase play a direct role in the initiation of replication?

1994 • 19 citations