Distinct pattern of p53 phosphorylation in human tumors

p53 Mutations in Human Cancers

1991 • 8,133 citations

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

1997 • 2,510 citations

p53: puzzle and paradigm.

1996 • 2,363 citations

DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2

1997 • 2,089 citations

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

1998 • 2,034 citations

Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

1998 • 1,734 citations

The p53 pathway

1999 • 1,322 citations

The complexity of p53 modulation: emerging patterns from divergent signals

1998 • 1,319 citations

DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2

2000 • 1,269 citations

DNA damage activates p53 through a phosphorylation–acetylation cascade

1998 • 1,194 citations

p53AIP1, a Potential Mediator of p53-Dependent Apoptosis, and Its Regulation by Ser-46-Phosphorylated p53

2000 • 1,155 citations

Pharmacological Rescue of Mutant p53 Conformation and Function

1999 • 794 citations

p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage

1999 • 764 citations

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

1999 • 690 citations

Human DNA-Activated Protein Kinase Phosphorylates Serines 15 and 37 in the Amino-Terminal Transactivation Domain of Human p53

1992 • 473 citations

ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

1998 • 471 citations

Phosphorylation of p53 Serine 15 Increases Interaction with CBP

1998 • 427 citations

Thermodynamic stability of wild-type and mutant p53 core domain

1997 • 401 citations

Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53.

1983 • 313 citations

Jun NH₂-Terminal Kinase Phosphorylation of p53 on Thr-81 Is Important for p53 Stabilization and Transcriptional Activities in Response to Stress

2001 • 290 citations

Damage-mediated Phosphorylation of Human p53 Threonine 18 through a Cascade Mediated by a Casein 1-like Kinase

2000 • 285 citations

p38 Kinase Mediates UV-induced Phosphorylation of p53 Protein at Serine 389

1999 • 280 citations

An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control

1998 • 241 citations

Mechanisms of switching on p53: a role for covalent modification?

1999 • 236 citations

Human p53 Is Phosphorylated on Serines 6 and 9 in Response to DNA Damage-inducing Agents

2000 • 125 citations

Two Distinct Mechanisms Regulate the Levels of a Cellular Tumor Antigen, p53

1983 • 104 citations

`Gain of function' phenotype of tumor-derived mutant p53 requires the oligomerization/nonsequence-specific nucleic acid-binding domain

1998 • 88 citations

Cell cycle regulators and their abnormalities in breast cancer

1998 • 45 citations

Phosphorylation of Human p53 on Thr-55

2000 • 43 citations

Analysis of JNK, Mdm2 and p14ARF contribution to the regulation of mutant p53 stability

2000 • 39 citations

Fine mapping and regulation of the association of p53 with p34cdc2

1998 • 29 citations

Untitled

1998 • 14 citations