Effects of monensin liposomes on the cytotoxicity, apoptosis and expression of multidrug resistance genes in doxorubicin-resistant human breast tumour (MCF-7/dox) cell-line

Pharmacology of drugs that alter multidrug resistance in cancer.

1990 • 970 citations

Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity

1990 • 618 citations

INTERACTIONS OF LIPOSOMES WITH MAMMALIAN CELLS

1978 • 408 citations

How cancer cells evade chemotherapy: sixteenth Richard and Hinda Rosenthal Foundation Award Lecture.

1993 • 357 citations

ATP binding cassette transporters and drug resistance in breast cancer.

2003 • 255 citations

Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil.

1988 • 205 citations

Multidrug Resistance and the Lung Resistance-Related Protein in Human Colon Carcinoma SW-620 Cells

1999 • 186 citations

Phospholipid Flippase Activity of the Reconstituted P-Glycoprotein Multidrug Transporter

2001 • 156 citations

Phosphatidylcholine and Phosphatidylethanolamine Behave as Substrates of the Human MDR1 P-Glycoprotein

1997 • 136 citations

Cellular and biochemical characterization of VX-710 as a chemosensitizer

1997 • 131 citations

Increased mdr-1/P-glycoprotein expression after treatment of human colon carcinoma cells with P-glycoprotein antagonists.

1993 • 125 citations

Potent and specific antitumor effects of an anti-CD22–targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma

2001 • 104 citations

Induction of apoptosis by cyclo-oxygenase-2 inhibitor NS398 through a cytochromeC-dependent pathway in esophageal cancer cells

2001 • 95 citations

Decreased Mutation Rate for Cellular Resistance to Doxorubicin and Suppression of mdrl Gene Activation by the Cyclosporin PSC 833

1995 • 83 citations

Safety and efficacy of the multidrug resistance inhibitor Incel (biricodar; VX-710) in combination with paclitaxel for advanced breast cancer refractory to paclitaxel.

2002 • 80 citations

Mobile ionophores are a novel class of P‐glycoprotein inhibitors

1994 • 78 citations

Evidence for transcriptional control of human mdr1 gene expression by verapamil in multidrug-resistant leukemic cells.

1995 • 69 citations

Reversal effects of nomegestrol acetate on multidrug resistance in adriamycin-resistant MCF7 breast cancer cell line

2001 • 69 citations

Modulation of P-Glycoprotein by Protein Kinase C.alpha. in a Baculovirus Expression System

1994 • 65 citations

Phospholipids as multidrug resistance modulators of the transport of epirubicin in human intestinal epithelial Caco-2 cell layers and everted gut sacs of rats

2000 • 62 citations

LIPOSOMAL DAUNORUBICIN OVERCOMES DRUG RESISTANCE IN HUMAN BREAST, OVARIAN AND LUNG CARCINOMA CELLS

2002 • 62 citations

Chemosensitisation and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP

1997 • 53 citations

MS-209, a quinoline-type reversal agent, potentiates antitumor efficacy of docetaxel in multidrug-resistant solid tumor xenograft models.

2002 • 47 citations

The carboxylic ionophore monensin inhibits active drug efflux and modulates in vitro resistance in daunorubicin resistant Ehrlich ascites tumor cells

1988 • 45 citations

Usefulness of Liposomes Loaded with Cytostatic Bile Acid Derivatives to Circumvent Chemotherapy Resistance of Enterohepatic Tumors

2003 • 43 citations

The multidrug-resistant human lung tumour cell line, DLKP-A10, expresses novel drug accumulation and sequestration systems

1997 • 39 citations

Carrier protein-monensin conjugates: enhancement of immunotoxin cytotoxicity and potential in tumor treatment.

1990 • 36 citations

Long-circulating monensin nanoparticles for the potentiation of immunotoxin and anticancer drugs

2001 • 31 citations

Stealth monensin liposomes as a potentiator of adriamycin in cancer treatment

1999 • 31 citations

γ‐Tocopheryl quinone stimulates apoptosis in drug‐sensitive and multidrug‐resistant cancer cells

2002 • 30 citations

Effect of PSC 833 liposomes and Intralipid on the transport of epirubicin in Caco-2 cells and rat intestines

2001 • 25 citations

Potent cytotoxic action of the immunotoxin SWA11-ricin A chain against human small cell lung cancer cell lines

1992 • 24 citations

MDR1 modulators improve the chemotherapy response of human hepatoblastoma to doxorubicin in vitro

2002 • 21 citations

Influence of cytotoxicity enhancers in combination with human serum on the activity of CD22-recombinant ricin A against B cell lines, chronic and acute lymphocytic leukemia cells

1999 • 20 citations

Monensin and verapamil do not alter intracellular localisation of daunorubicin in multidrug resistant human KB cells

1996 • 19 citations

Reversal of Multidrug Resistance‐Associated Protein‐Mediated Daunorubicin Resistance by Camptothecin

2002 • 17 citations

Stealth monensin immunoliposomes as potentiator of immunotoxins in vitro

2001 • 16 citations

Enhanced drug-induced apoptosis associated with P-glycoprotein overexpression is specific to antimicrotubule agents.

2003 • 15 citations

Conjugation of anti-My9 antibody to stealth monensin liposomes and the effect of conjugated liposomes on the cytotoxicity of immunotoxin

2001 • 14 citations

Effect of monensin liposomes on the cytotoxicity of anti-My9-bR immunotoxin

2003 • 10 citations

Reversal of multidrug resistance to epirubicin by cyclosporin A in liposomes or intralipid.

2001 • 9 citations

Two types of interaction between P-glycoprotein and ionophore antibiotics

1991 • 9 citations

Enhancement of ricin toxin a chain immunotoxin activity: Synthesis, ionophoretic ability, and in vitro activity of monensin derivatives

1996 • 9 citations

INTRINSIC CYTOTOXICITY AND REVERSAL OF MULTIDRUG-RESISTANCE BY MONENSIN IN KB PARENT AND MDR CELLS

1993 • 7 citations

Effect of mitoxantrone liposomes on multidrug-resistant breast cancer cells.

2000 • 6 citations

Influence of chemosensitizers on resistance mechanisms in daunorubicin-resistant Ehrlich ascites tumour cells

2002 • 3 citations