Lysis of a Broad Range of Epithelial Tumour Cells by Human γδ T Cells: Involvement of NKG2D ligands and T‐cell Receptor‐ versus NKG2D‐dependent Recognition

ULBPs, Novel MHC Class I–Related Molecules, Bind to CMV Glycoprotein UL16 and Stimulate NK Cytotoxicity through the NKG2D Receptor

2001 • 1,190 citations

Broad tumor-associated expression and recognition by tumor-derived γδ T cells of MICA and MICB

1999 • 1,006 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

Regulation of Cutaneous Malignancy by γδ T Cells

2001 • 945 citations

Human T Cell Receptor γδ Cells Recognize Endogenous Mevalonate Metabolites in Tumor Cells

2003 • 782 citations

Stimulation of γδ T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma

2000 • 630 citations

A Role for Skin γδ T Cells in Wound Repair

2002 • 596 citations

Protection of the intestinal mucosa by intraepithelial γδ T cells

2002 • 462 citations

Immunoregulation in the tissues by γδ T cells

2003 • 412 citations

MICA Engagement by Human Vγ2Vδ2 T Cells Enhances Their Antigen-Dependent Effector Function

2001 • 394 citations

Adaptive Immune Response of Vγ2Vδ2 ⁺ T Cells During Mycobacterial Infections

2002 • 368 citations

A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform

2003 • 302 citations

Activation of Vγ9Vδ2 T Cells by NKG2D

2005 • 287 citations

Tumor Recognition following Vγ9Vδ2 T Cell Receptor Interactions with a Surface F1-ATPase-Related Structure and Apolipoprotein A-I

2005 • 281 citations

V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer.

1995 • 276 citations

Perspectives of γδ T Cells in Tumor Immunology

2007 • 248 citations

Proteolytic Release of Soluble UL16-Binding Protein 2 from Tumor Cells

2006 • 232 citations

Soluble MICA in malignant diseases

2005 • 225 citations

Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: a pilot study

2006 • 219 citations

TGF- and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells

2006 • 206 citations

Vγ9Vδ2 T Cell Response to Colon Carcinoma Cells

2005 • 194 citations

Human Vγ9Vδ2 T cells: promising new leads for immunotherapy of infections and tumors

2006 • 192 citations

In Vivo Immunomanipulation of Vγ9Vδ2 T Cells with a Synthetic Phosphoantigen in a Preclinical Nonhuman Primate Model

2005 • 187 citations

Phosphostim-Activated γδ T Cells Kill Autologous Metastatic Renal Cell Carcinoma

2005 • 179 citations

Gamma/delta T cell clones and natural killer cell clones mediate distinct patterns of non-major histocompatibility complex-restricted cytolysis.

1990 • 176 citations

Vδ1 T Lymphocytes from B-CLL Patients Recognize ULBP3 Expressed on Leukemic B Cells and Up-Regulated by Trans -Retinoic Acid

2004 • 171 citations

T cell receptor/CD3-signaling induces death by apoptosis in human T cell receptor gamma delta + T cells.

1991 • 167 citations

Human intestinal Vdelta1+ lymphocytes recognize tumor cells of epithelial origin.

1996 • 152 citations

Characterization of Tumor Reactivity of Human Vγ9Vδ2 γδ T Cells In Vitro and in SCID Mice In Vivo

2004 • 150 citations

Chemical Synthesis and Biological Activity of Bromohydrin Pyrophosphate, a Potent Stimulator of Human γδ T Cells

2001 • 148 citations

Targeting of Tumor Cells for Human γδ T Cells by Nonpeptide Antigens

2001 • 146 citations

Human γδ T cells: a nonredundant system in the immune-surveillance against cancer

2002 • 144 citations

Chemotherapy and zoledronate sensitize solid tumour cells to Vγ9Vδ2 T cell cytotoxicity

2007 • 144 citations

Release of MICB Molecules by Tumor Cells: Mechanism and Soluble MICB in Sera of Cancer Patients

2006 • 141 citations

Cytotoxic effects of γδ T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy

2005 • 139 citations

Effector γδ T cells and tumor cells as immune targets of zoledronic acid in multiple myeloma

2005 • 121 citations

Soluble ULBP suppresses natural killer cell activity via down-regulating NKG2D expression

2006 • 115 citations

Soluble MIC is elevated in the serum of patients with pancreatic carcinoma diminishing γδ T cell cytotoxicity

2006 • 110 citations

Selective lysis of autologous tumor cells by recurrent gamma delta tumor-infiltrating lymphocytes from renal carcinoma.

1995 • 110 citations

Antigen Recognition by Human γδ T Lymphocytes

2000 • 104 citations

Vγ9/Vδ2 T cell activation induced by bacterial low molecular mass compounds depends on the 1-deoxy-d-xylulose 5-phosphate pathway of isoprenoid biosynthesis

1999 • 94 citations

The importance of gd T cells in the resolution of pathogen‐induced inflammatory immune responses

2000 • 93 citations

Activated γδ T cells express the natural cytotoxicity receptor natural killer p44 and show cytotoxic activity against myeloma cells

2006 • 83 citations

γδ T cells: A new frontier for immunotherapy?

2005 • 69 citations

Life and death of a superantigen-reactive human CD4⁺ T cell clone: staphylococcal enterotoxins induce death by apoptosis but simultaneously trigger a proliferative response in the presence of HLA-DR⁺ antigen-presenting cells

1992 • 63 citations

Potential of human γδ T lymphocytes for immunotherapy of cancer

2004 • 60 citations

Non-peptide antigens activating human Vγ9/Vδ2 T lymphocytes

2004 • 58 citations

Combination Immunotherapy with Clinical-Scale Enriched Human γδ T cells, hu14.18 Antibody, and the Immunocytokine Fc-IL7 in Disseminated Neuroblastoma

2005 • 43 citations

Spontaneous resistance to acute T-cell leukaemias in TCRVγ1.1Jγ4Cγ4 transgenic mice

1995 • 40 citations

Innate Anti-breast Cancer Immunity of Apoptosis-resistant Human γδ-T cells

2005 • 39 citations

NKG2D-independent suppression of T cell proliferation by H60 and MICA

2005 • 38 citations

Peripheral γδ T-lymphocytes as an innovative tool in immunotherapy for metastatic renal cell carcinoma

2005 • 36 citations

Human ???? T Cells From G-CSF-Mobilized Donors Retain Strong Tumoricidal Activity and Produce Immunomodulatory Cytokines After Clinical-Scale Isolation

2004 • 35 citations

Functional analysis of TCR γδ+ T cells in tumour-infiltrating lymphocytes (TIL) of human pancreatic cancer

1993 • 30 citations

Immunosurveillance by γδ T Cells: Focus on the Murine System

2005 • 20 citations

Dysregulation of the γδ T cell repertoire in patients with acute leukemia: Implications for cellular immunotherapy

2005 • 3 citations