Antigen Recognition by Human γδ T Lymphocytes

Functional MRI evidence for adult motor cortex plasticity during motor skill learning

1995 • 1,851 citations

Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate

1993 • 1,158 citations

Recognition of Stress-Induced MHC Molecules by Intestinal Epithelial γδ T Cells

1998 • 1,134 citations

The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants†

1999 • 1,128 citations

Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium.

1996 • 1,010 citations

Broad tumor-associated expression and recognition by tumor-derived γδ T cells of MICA and MICB

1999 • 1,006 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands

1994 • 685 citations

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

1984 • 652 citations

Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire.

1990 • 510 citations

CDR3 length in antigen-specific immune receptors.

1994 • 503 citations

Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells

1995 • 468 citations

The nature of major histocompatibility complex recognition by γδ T cells

1994 • 407 citations

Nonpeptide ligands for human gamma delta T cells.

1994 • 373 citations

Human γδ T Cells Recognize Alkylamines Derived from Microbes, Edible Plants, and Tea

1999 • 368 citations

Recognition by Human V _γ 9/V _δ 2 T Cells of a GroEL Homolog on Daudi Burkitt's Lymphoma Cells

1990 • 357 citations

A large fraction of human peripheral blood gamma/delta + T cells is activated by Mycobacterium tuberculosis but not by its 65-kD heat shock protein.

1990 • 331 citations

Implication of γδ T cells in the human immune response to cytomegalovirus

1999 • 316 citations

Intraepithelial T Cells of the TcRγ/δ⁺CD8⁻ and Vδ1/Jδ1⁺ Phenotypes are Increased in Coeliac Disease

1989 • 311 citations

Recognition of a Peptide Antigen by Heat Shock--reactive γδ T Lymphocytes

1990 • 291 citations

V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer.

1995 • 276 citations

Requirement for γδ T Cells in Allergic Airway Inflammation

1998 • 268 citations

A major fraction of human intraepithelial lymphocytes simultaneously expresses the γ/δ T cell receptor, the CD8 accessory molecule and preferentially uses the V_δ1 gene segment

1991 • 261 citations

Primary responses of human T cells to mycobacteria: a frequent set of γ/δ T cells are stimulated by protease‐resistant ligands

1990 • 243 citations

Immunoregulatory Functions of γδ T Cells

1998 • 201 citations

CD4+ alpha beta T cell and gamma delta T cell responses to Mycobacterium tuberculosis. Similarities and differences in Ag recognition, cytotoxic effector function, and cytokine production.

1995 • 184 citations

Negative regulation of airway responsiveness that is dependent on γδ T cells and independent of αβ T cells

1999 • 180 citations

Crystal Structure of the MHC Class I Homolog MIC-A, a γδ T Cell Ligand

1999 • 178 citations

Biochemistry of Polyisoprenoid Biosynthesis

1976 • 178 citations

Early activation of human V gamma 9V delta 2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands.

1995 • 177 citations

Human TCR-gamma+/delta+, CD8+ T lymphocytes recognize tetanus toxoid in an MHC-restricted fashion.

1989 • 170 citations

Sentinel function of broadly reactive human γδ T cells

1997 • 156 citations

Gamma/delta T cells and the diagnosis of coeliac disease

1991 • 133 citations

Plasmodium falciparum stimuli for human gammadelta T cells are related to phosphorylated antigens of mycobacteria

1996 • 131 citations

Structure of the Vδ domain of a human γδ T-cell antigen receptor

1998 • 130 citations

Control of B cell lymphoma recognition via natural killer inhibitory receptors implies a role for human Vγ9/Vδ2 T cells in tumor immunity

1997 • 120 citations

CDR3-independent gamma delta V delta 1+ T cell expansion in the peripheral blood of HIV-infected persons.

1995 • 120 citations

Phosphoantigen‐Reactive Vγ9Vδ2 T Lymphocytes Suppress In Vitro Human Immunodeficiency Virus Type 1 Replication by Cell‐Released Antiviral Factors Including CC Chemokines

1999 • 116 citations

3-Formyl-1-butyl Pyrophosphate A Novel Mycobacterial Metabolite-activating Human γδ T Cells

1999 • 114 citations

Expansion of Vγ9Vδ2 T Cells Is Triggered byFrancisella tularensis-Derived Phosphoantigens in Tularemia but Not after Tularemia Vaccination

1998 • 111 citations

Preferential expansion of V_γ9 V_δ2 T cells following stimulation of peripheral blood lymphocytes with extracts of Plasmodium falciparum

1992 • 108 citations

Apoptosis of Fashigh CD4+ Synovial T Cells by Borrelia-reactive Fas-ligandhigh γδ T Cells in Lyme Arthritis

1996 • 106 citations

Human V gamma 9-V delta 2 T cell receptor-gamma delta lymphocytes show specificity to Daudi Burkitt's lymphoma cells.

1990 • 98 citations

Isoprenoid biosynthesis in bacteria: Two different pathways?

1993 • 97 citations

The Recognition of the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule, T10, by the γδ T Cell, G8

1997 • 96 citations

Changes in Human Mucosal γδ T Cell Repertoire and Function Associated with the Disease Process in Inflammatory Bowel Disease

1997 • 94 citations

Primary activation of V gamma 9-expressing gamma delta T cells by Mycobacterium tuberculosis. Requirement for Th1-type CD4 T cell help and inhibition by IL-10.

1994 • 94 citations

Vγ9/Vδ2 T cell activation induced by bacterial low molecular mass compounds depends on the 1-deoxy-d-xylulose 5-phosphate pathway of isoprenoid biosynthesis

1999 • 94 citations

Human gamma delta T cells recognize heat shock protein-60 on oral tumor cells

1999 • 83 citations

Dual antigenic recognition by cloned human gamma delta T cells.

1992 • 75 citations

γδ T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells

1996 • 75 citations

Comparative analysis of αβ and γδ T cell activation by Mycobacterium tuberculosis and isopentenyl pyrophosphate

1997 • 74 citations

Stimulation of γδ T cells by phosphoantigens

1996 • 69 citations

Identification of the complete expressed human TCR V gamma repertoire by flow cytometry

1997 • 65 citations

Preferential activation and expansion of human peripheral blood gamma delta T cells in response to Toxoplasma gondii in vitro and their cytokine production and cytotoxic activity against T. gondii-infected cells.

1995 • 64 citations

Intercellular interactions and cytokine responsiveness of peritoneal alpha/beta and gamma/delta T cells from Listeria-infected mice: synergistic effects of interleukin 1 and 7 on gamma/delta T cells.

1993 • 63 citations

A Mycobacterial Heat-Shock Protein-Responsive T Cell Clone Also Responds to the Homologous Human Heat-Shock Protein: A Possible Link between Infection and Autoimmunity

1991 • 62 citations

Analysis of the TCR Vgamma repertoire in healthy donors and HIV-1- infected individuals

1998 • 57 citations

Lyme arthritis synovial gamma delta T cells respond to Borrelia burgdorferi lipoproteins and lipidated hexapeptides.

1998 • 54 citations

?? T cells, their T cell receptor usage and role in human diseases

1999 • 48 citations

Analysis of γδ region usage in normal and diseased human intestinal biopsies and peripheral blood by polymerase chain reaction (PCR) and flow cytometry

1995 • 42 citations

Phosphoantigen activation induces surface translocation of intracellular CD94/NKG2A class I receptor on CD94− peripheral Vγ9 Vδ2 T cells but not on CD94− thymic or mature γ δ T cell clones

1998 • 38 citations

Cross‐talk between Vβ8⁺ and γδ⁺ T lymphocytes in contact sensitivity

1998 • 32 citations

γδ T cell responses to activated T cells in multiple sclerosis patients induced by T cell vaccination

1998 • 29 citations

Activation of human γδ T-cell by heat-treated mistletoe plant extracts

1996 • 26 citations

Human γδ T‐cell recognition of Yersinia enterocolitica

1997 • 26 citations

Generation of Human γδ T-Cell Repertoires

1999 • 20 citations

Recognition by human gut γδ cells of stress inducible major histocompatibility molecules on enterocytes

1998 • 19 citations

Cross‐talk between γδ T lymphocytes and immune cells in humoral response

1998 • 11 citations

Acquisition of a stimulatory activity for Vγ9/Vδ2 T cells by a Burkitt’s lymphoma cell line without loss of HLA class I expression

1999 • 10 citations

Isoprenoid biosynthesis in bacteria: Two different pathways?

1993 • 2 citations

Deleted Work

1955 • 0 citations