Vγ9/Vδ2 T cell activation induced by bacterial low molecular mass compounds depends on the 1-deoxy-d-xylulose 5-phosphate pathway of isoprenoid biosynthesis

Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate

1993 • 1,158 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

Gamma/Delta Cells

1993 • 819 citations

Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands

1994 • 685 citations

Dictionary of Terpenoids

1991 • 631 citations

A 1-deoxy- <scp>d</scp> -xylulose 5-phosphate reductoisomerase catalyzing the formation of 2- C -methyl- <scp>d</scp> -erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis

1998 • 460 citations

Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy- <scp>d</scp> -xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol

1997 • 446 citations

Nonpeptide ligands for human gamma delta T cells.

1994 • 373 citations

Recognition by Human V _γ 9/V _δ 2 T Cells of a GroEL Homolog on Daudi Burkitt's Lymphoma Cells

1990 • 357 citations

Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of <scp>d</scp> -1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis

1998 • 352 citations

A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway

1998 • 351 citations

A large fraction of human peripheral blood gamma/delta + T cells is activated by Mycobacterium tuberculosis but not by its 65-kD heat shock protein.

1990 • 331 citations

gamma/delta and other unconventional T lymphocytes: what do they see and what do they do?

1996 • 306 citations

RECOGNITION BY γ/δ T CELLS

1996 • 277 citations

Primary responses of human T cells to mycobacteria: a frequent set of γ/δ T cells are stimulated by protease‐resistant ligands

1990 • 243 citations

Biochemistry of Polyisoprenoid Biosynthesis

1976 • 178 citations

Human Vγ9‐Vδ2 cells are stimulated in a crossreactive fashion by a variety of phosphorylated metabolites

1995 • 168 citations

Target cell lysis and IL-2 secretion by gamma/delta T lymphocytes after activation with bacteria.

1990 • 167 citations

Sentinel function of broadly reactive human γδ T cells

1997 • 156 citations

Gamma/Delta T Cells

1993 • 146 citations

Simultaneous operation of the mevalonate and non-mevalonate pathways in the biosynthesis of isopentenly diphosphate in Streptomyces aeriouvifer

1996 • 124 citations

Phosphate is essential for stimulation of Vγ9Vδ2 T lymphocytes by mycobacterial low molecular weight ligand

1994 • 100 citations

Isoprenoid biosynthesis in bacteria: Two different pathways?

1993 • 97 citations

Plasmodium falciparum merozoites primarily stimulate the V_γ9 subset of human γ/δ T cells

1991 • 93 citations

Incorporation of 2-C-Methyl-d-erythritol, a Putative Isoprenoid Precursor in the Mevalonate-Independent Pathway, into Ubiquinone and Menaquinone of Escherichia coli

1997 • 92 citations

Biosynthesis of , a putative C5 intermediate in the mevalonate independent pathway for isoprenoid biosynthesis

1997 • 86 citations

The structure of bactoprenol, a lipid formed by lactobacilli from mevalonic acid

1966 • 74 citations

Induction of human TCRγδ⁺ and TCRγδ⁻ CD2 ⁺ CD3 ⁻ double negative lymphocytes by bacterial stimulation

1990 • 61 citations

Distribution of mevalonate and glyceraldehyde 3-phosphate/pyruvate routes for isoprenoid biosynthesis in some Gram-negative bacteria and mycobacteria

1998 • 53 citations

Early steps of isoprenoid biosynthesis in Escherichia coli

1991 • 51 citations

Analysis of phosphorylated carbohydrates by high-performance liquid chromatography–electrospray ionization tandem mass spectrometry utilising a β-cyclodextrin bonded stationary phase

1998 • 47 citations

A novel nucleotide‐containing antigen for human blood γδ T lymphocytes

1996 • 47 citations

Incorporation of [2,3-13C2]- and [2,4-13C2]-d-1-Deoxyxylulose into Ubiquinone of Escherichia coli via the Mevalonate-Independent Pathway for Isoprenoid Biosynthesis

1998 • 47 citations

On the Utilization in vivo of Lycopene and Phytoene as Precursors for the Formation of Carotenoid Glucoside Ester and on the Regulation of Carotenoid Biosynthesis in Myxococcus fulvus

1975 • 33 citations

Identification of Prenol Intermediates of Wall Biosynthesis in Growing Cells of Lactobacillus plantarum

1973 • 16 citations

Studies on isoprenoid biosynthesis with bacterial intact cells

1983 • 15 citations

The metabolism of acetate and mevalonic acid by lactobacilli III. Studies on the unsaponifiable lipids derived from mevalonic acid

1962 • 14 citations

On the Enzymatic Synthesis of lsopentenylpyrophosphate from Mevalonate with Staphylococcus

1964 • 13 citations

The biosynthesis of C55 polyprenols by a cell-free preparation of Lactobacillus plantarum

1972 • 13 citations

A cell-free system from Streptococcus faecium for studies on the biosynthesis of triterpenoid carotenoids

1982 • 13 citations

Microscopic observations on commercial sepharose: Deviations from normal bead‐structure

1975 • 11 citations

Incorporation of radioactive mevalonate into C50 and C55 prenols by Streptococcus mutans

1973 • 10 citations

The biosynthesis of triterpenoid carotenoids in Streptococcus faecium UNH 564P

1982 • 9 citations

An In Vitro Model for the Expansion of Vγ9δ2 T Lymphocytes During Development

1994 • 9 citations

Occurrence of squalene and dehydrosqualene in streptomycetes

1985 • 8 citations

High resolution gas chromatography—Mass spectral analysis of carbohydrates using methoxyoxime acetates

1993 • 7 citations

Specific 14C-labeling of isoprenoids of intact E. coli cells.

1984 • 3 citations