Human Vγ9Vδ2 T cells: promising new leads for immunotherapy of infections and tumors

γδ Cells: A Right Time and a Right Place for a Conserved Third Way of Protection

2000 • 1,107 citations

CD1: Antigen Presentation and T Cell Function

2004 • 1,025 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

Gamma/Delta Cells

1993 • 819 citations

Coordinated Induction by IL15 of a TCR-Independent NKG2D Signaling Pathway Converts CTL into Lymphokine-Activated Killer Cells in Celiac Disease

2004 • 809 citations

Human T Cell Receptor γδ Cells Recognize Endogenous Mevalonate Metabolites in Tumor Cells

2003 • 782 citations

Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands

1994 • 685 citations

Professional Antigen-Presentation Function by Human γδ T Cells

2005 • 668 citations

γδ T cells for immune therapy of patients with lymphoid malignancies

2003 • 525 citations

Autoreactivity by design: innate B and T lymphocytes

2001 • 409 citations

MICA Engagement by Human Vγ2Vδ2 T Cells Enhances Their Antigen-Dependent Effector Function

2001 • 394 citations

Dendritic cell maturation by innate lymphocytes

2005 • 390 citations

Human γδ T Cells Recognize Alkylamines Derived from Microbes, Edible Plants, and Tea

1999 • 368 citations

Endothelial cell surface F ₁ -F _O ATP synthase is active in ATP synthesis and is inhibited by angiostatin

2001 • 313 citations

Activation of Vγ9Vδ2 T Cells by NKG2D

2005 • 287 citations

Tumor Recognition following Vγ9Vδ2 T Cell Receptor Interactions with a Surface F1-ATPase-Related Structure and Apolipoprotein A-I

2005 • 281 citations

RECOGNITION BY γ/δ T CELLS

1996 • 277 citations

A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen‐containing bisphosphonates

2006 • 275 citations

Reciprocal Activating Interaction Between Dendritic Cells and Pamidronate-Stimulated γδ T Cells: Role of CD86 and Inflammatory Cytokines

2005 • 207 citations

Vγ9Vδ2 T Cell Response to Colon Carcinoma Cells

2005 • 194 citations

The function of γδ T cells in innate immunity

2005 • 191 citations

In Vivo Immunomanipulation of Vγ9Vδ2 T Cells with a Synthetic Phosphoantigen in a Preclinical Nonhuman Primate Model

2005 • 187 citations

Phosphostim-Activated γδ T Cells Kill Autologous Metastatic Renal Cell Carcinoma

2005 • 179 citations

Early activation of human V gamma 9V delta 2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands.

1995 • 177 citations

Flexible migration program regulates γδ T-cell involvement in humoral immunity

2003 • 174 citations

Ontogeny of γδ T Cells in Humans

2004 • 167 citations

Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach.

2001 • 165 citations

Patterns of Chemokine Receptor Expression on Peripheral Blood γδ T Lymphocytes: Strong Expression of CCR5 Is a Selective Feature of Vδ2/Vγ9 γδ T Cells

2002 • 152 citations

Characterization of Tumor Reactivity of Human Vγ9Vδ2 γδ T Cells In Vitro and in SCID Mice In Vivo

2004 • 150 citations

Differentiation of Resting Human Peripheral Blood γδ T Cells toward Th1- or Th2-Phenotype

2001 • 136 citations

Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach

2001 • 129 citations

Peripheral selection of antigen receptor junctional features in a major human γδ subset

1993 • 129 citations

Human Keratinocytes Release ATP and Utilize Three Mechanisms for Nucleotide Interconversion at the Cell Surface

2005 • 118 citations

Potentiation of Antigen-Stimulated Vγ9Vδ2 T Cell Cytokine Production by Immature Dendritic Cells (DC) and Reciprocal Effect on DC Maturation

2006 • 114 citations

Differential requirements for antigen or homeostatic cytokines for proliferation and differentiation of human Vγ9Vδ2 naive, memory and effector T cell subsets

2005 • 104 citations

Vγ9/Vδ2 T cell activation induced by bacterial low molecular mass compounds depends on the 1-deoxy-d-xylulose 5-phosphate pathway of isoprenoid biosynthesis

1999 • 94 citations

Antiviral reactivities of γδ T cells

2005 • 94 citations

Alkylamines cause Vγ9Vδ2 T-cell activation and proliferation by inhibiting the mevalonate pathway

2005 • 92 citations

Effect Of Human Natural Killer and γδ T Cells on the Growth of Human Autologous Melanoma Xenografts in SCID Mice

2004 • 86 citations

内皮細胞表面F1‐F0ATPシンターゼはATP合成に働き、アンギオスタチンにより阻害される

2001 • 82 citations

Sensing cell stress and transformation through Vγ9Vδ2 T cell-mediated recognition of the isoprenoid pathway metabolites

2005 • 80 citations

Regulation of skin cell homeostasis by gamma delta T cells

2004 • 74 citations

Mortalin–MPD (mevalonate pyrophosphate decarboxylase) interactions and their role in control of cellular proliferation

2003 • 73 citations

Drug-Induced Expansion and Differentiation of Vγ9Vδ2 T Cells In Vivo: The Role of Exogenous IL-2

2005 • 71 citations

The interplay between classical and alternative isoprenoid biosynthesis controls γδ T cell bioactivity of Listeria monocytogenes

2004 • 70 citations

Mycobacteria‐reactive γδ T cells in HIV‐infected individuals: lack of Vγ9 cell responsiveness is due to deficiency of antigen‐specific CD4 T helper type 1 cells

1996 • 43 citations

Lyme Arthritis Synovial γδ T Cells Instruct Dendritic Cells via Fas Ligand

2005 • 39 citations

Expression and synthesis of fibroblast growth factor-9 in human γδ T-lymphocytes. Response to isopentenyl pyrophosphate and TGF-β1/IL-15

2004 • 34 citations

Homing and memory patterns of human γδ T cells in physiopathological situations

2005 • 28 citations

Gamma delta T cell responses associated with the development of tuberculosis in health care workers

2004 • 18 citations

Analysis of mechanism for human γδ T cell recognition of nonpeptide antigens

2005 • 12 citations

Expression of metalloproteinase‐7 (matrilysin) in human blood and bronchoalveolar Gamma/Delta T‐lymphocytes. Selective upregulation by the soluble non‐peptidic mycobacterial phosphoantigen (isopentenyl pyrophosphate)

2005 • 9 citations