Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

1996 • 3,041 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

Cholesterol Modification of Hedgehog Signaling Proteins in Animal Development

1996 • 1,342 citations

Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

1995 • 1,060 citations

Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling

1997 • 1,019 citations

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

1994 • 869 citations

Two Critical Periods of Sonic Hedgehog Signaling Required for the Specification of Motor Neuron Identity

1996 • 866 citations

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog.

1996 • 829 citations

Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds

1993 • 800 citations

A mouse model of Greig cephalo–polysyndactyly syndrome: the extra–toesJ mutation contains an intragenic deletion of the Gli3 gene

1993 • 715 citations

Control of cell pattern in the developing nervous system: Polarizing activity of the floor plate and notochord

1991 • 698 citations

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo

1993 • 680 citations

A binding site for Gli proteins is essential for HNF-3β floor plate enhancer activity in transgenics and can respond to Shh in vitro

1997 • 667 citations

Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor

1997 • 658 citations

Early Stages of Motor Neuron Differentiation Revealed by Expression of Homeobox Gene Islet-1

1992 • 638 citations

Gli1 is a target of Sonic hedgehog that induces ventral neural tube development

1997 • 625 citations

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development

1997 • 606 citations

Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants

1995 • 491 citations

Induction of midbrain dopaminergic neurons by Sonic hedgehog

1995 • 481 citations

Expression of Three Mouse Homologs of the Drosophila Segment Polarity Gene cubitus interruptus, Gli, Gli-2, and Gli-3, in Ectoderm- and Mesoderm-Derived Tissues Suggests Multiple Roles during Postimplantation Development

1994 • 478 citations

Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate

1993 • 470 citations

The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system

1990 • 383 citations

Developmental expression of a novel murine homeobox gene (Chx10): Evidence for roles in determination of the neuroretina and inner nuclear layer

1994 • 379 citations

Distribution of Sonic hedgehog peptides in the developing chick and mouse embryo

1995 • 376 citations

Hedgehog Elicits Signal Transduction by Means of a Large Complex Containing the Kinesin-Related Protein Costal2

1997 • 371 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 356 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 326 citations

Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum

1991 • 325 citations

Cooperation of BMP7 and SHH in the Induction of Forebrain Ventral Midline Cells by Prechordal Mesoderm

1997 • 292 citations

Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS

1994 • 290 citations

HNF-3β as a regulator of floor plate development

1994 • 287 citations

Control of Cell Pattern in the Neural Tube by the Zinc Finger Transcription Factor and Oncogene Gli-1

1997 • 275 citations

Induction of floor plate differentiation by contact-dependent, homeogenetic signals

1993 • 271 citations

Dorsal-ventral patterning and differentiation of noggin-induced neural tissue in the absence of mesoderm

1995 • 215 citations

Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development

1997 • 199 citations

Catching a Gli-mpse of Hedgehog

1997 • 198 citations

Expression Patterns of Two Murine Homologs ofDrosophila Single-MindedSuggest Possible Roles in Embryonic Patterning and in the Pathogenesis of Down Syndrome

1996 • 198 citations

Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation

1995 • 165 citations

Expression Patterns of Two Murine Homologs ofDrosophila Single-MindedSuggest Possible Roles in Embryonic Patterning and in the Pathogenesis of Down Syndrome

1996 • 161 citations

Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice

1997 • 152 citations

Mediation of Sonic Hedgehog-Induced Expression of COUP-TFII by a Protein Phosphatase

1997 • 149 citations

Expression patterns of developmental control genes in normal and Engrailed-1 mutant mouse spinal cord reveal early diversity in developing interneurons.

1997 • 123 citations

Early Stages of Notochord and Floor Plate Development in the Chick Embryo Defined by Normal and Induced Expression of HNF-3β

1995 • 119 citations

Expression Patterns of Developmental Control Genes in Normal andEngrailed-1Mutant Mouse Spinal Cord Reveal Early Diversity in Developing Interneurons

1997 • 109 citations

Ontological study of calbindin‐D_28k‐like and parvalbumin‐like immunoreactivities in rat spinal cord and dorsal root ganglia

1990 • 81 citations

Early appearance of tyrosine hydroxylase immunoreactive cells in the mesencephalon of mouse embryos

1990 • 72 citations

Conservation of the C.elegans tra-2 3'UTR translational control

1997 • 63 citations

Pattern Formation: Hedgehog points the way

1994 • 59 citations

Expression of wingless in the Drosophila embryo: a conserved cis-acting element lacking conserved Ci-binding sites is required for patched-mediated repression

1998 • 51 citations

Hedgehog signalling: Ci complex cuts and clasps

1997 • 30 citations

Antisense inhibition of Engrailed genes in mouse embryos reveals roles for these genes in craniofacial and neural tube development

1995 • 24 citations