Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Mutations affecting segment number and polarity in Drosophila

1980 • 4,280 citations

Sonic hedgehog mediates the polarizing activity of the ZPA

1993 • 2,313 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

1994 • 1,346 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

1993 • 1,086 citations

Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes

1994 • 1,005 citations

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

1994 • 869 citations

Neurotrophic factors: from molecule to man

1994 • 800 citations

Control of cell pattern in the developing nervous system: Polarizing activity of the floor plate and notochord

1991 • 698 citations

Early Stages of Motor Neuron Differentiation Revealed by Expression of Homeobox Gene Islet-1

1992 • 638 citations

Patterning of mammalian somites by surface ectoderm and notochord: Evidence for sclerotome induction by a hedgehog homolog

1994 • 594 citations

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog

1992 • 585 citations

Autoproteolysis in hedgehog protein biogenesis

1994 • 541 citations

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

1995 • 505 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate

1993 • 470 citations

The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system

1991 • 432 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 356 citations

Activin signalling and response to a morphogen gradient

1994 • 328 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 326 citations

Proteolytic Processing Yields Two Secreted Forms of Sonic hedgehog

1995 • 309 citations

Mesodermal Control of Neural Cell Identity: Floor Plate Induction by the Notochord

1990 • 300 citations

Products, genetic linkage and limb patterning activity of a murine hedgehog gene

1994 • 298 citations

HNF-3β as a regulator of floor plate development

1994 • 287 citations

Induction of floor plate differentiation by contact-dependent, homeogenetic signals

1993 • 271 citations

Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos

1989 • 264 citations

Effect of the notochord on the differentiation of a floor plate area in the neural tube of the chick embryo

1988 • 246 citations

Neurotrophin 3 is a mitogen for cultured neural crest cells.

1992 • 192 citations

Sequential expression of HNF-3β and HNF-3α by embryonic organizing centers: the dorsal lip/node, notochord and floor plate

1993 • 189 citations

Perturbation of neuronal differentiation and axon guidance in the spinal cord of mouse embryos lacking a floor plate: analysis of Danforth’s shorttail mutation

1991 • 168 citations

Sonic hedgehog: a common signal for ventral patterning along the rostrocaudal axis of the neural tube.

1995 • 132 citations

Developmental changes in unique cell surface antigens of chick embryo spinal motoneurons and ganglion cells

1984 • 126 citations

Early Stages of Notochord and Floor Plate Development in the Chick Embryo Defined by Normal and Induced Expression of HNF-3β

1995 • 119 citations

Restrictions to Floor Plate Induction by hedgehog and Winged-Helix Genes in the Neural Tube of Frog Embryos

1995 • 107 citations

The Effect of the Floor Plate on Pattern and Polarity in the Developing Central Nervous System

1991 • 77 citations

Secretion of the amino-terminal fragment of the Hedgehog protein is necessary and sufficient for hedgehog signalling in Drosophila

1995 • 76 citations

Neurotrophin‐3 affects proliferation and differentiation of distinct neural crest cells and is present in the early neural tube of avian embryos

1993 • 63 citations

Neurotrophin 3 stimulates the differentiation of motoneurons from avian neural tube progenitor cells.

1994 • 54 citations