Induction of midbrain dopaminergic neurons by Sonic hedgehog

Handbook of Chemical Neuroanatomy

1986 • 4,276 citations

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1987 • 2,189 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

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1994 • 1,950 citations

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1988 • 1,235 citations

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1993 • 1,166 citations

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

1993 • 1,086 citations

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

1995 • 886 citations

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

1994 • 869 citations

Drugs, Neurotransmitters, and Schizophrenia

1974 • 832 citations

Ligands for EPH-Related Receptor Tyrosine Kinases that Require Membrane Attachment or Clustering for Activity

1994 • 720 citations

Control of cell pattern in the developing nervous system: Polarizing activity of the floor plate and notochord

1991 • 698 citations

Chemotropic guidance of developing axons in the mammalian central nervous system

1988 • 681 citations

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo

1993 • 680 citations

Ontogeny of monoamine neurons in the locus coeruleus, raphe nuclei and substantia nigra of the rat. I. Cell differentiation

1974 • 653 citations

Dopamine D4 receptors elevated in schizophrenia

1993 • 632 citations

Sonic hedgehog induces the differentiation of ventral forebrain neurons: A common signal for ventral patterning within the neural tube

1995 • 542 citations

Autoproteolysis in hedgehog protein biogenesis

1994 • 541 citations

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

1995 • 505 citations

The pre- and postnatal development of the dopaminergic cell groups in the ventral mesencephalon and the dopaminergic innervation of the striatum of the rat

1988 • 499 citations

Light‐microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. II. Late ontogeny

1981 • 497 citations

Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants

1995 • 491 citations

Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate

1993 • 470 citations

Ontogeny of monoamine neurons in the locus coeruleus, raphe nuclei and substantia nigra of the rat

1975 • 411 citations

Long-range sclerotome induction by sonic hedgehog: Direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway

1995 • 341 citations

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function.

1993 • 329 citations

Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development

1995 • 315 citations

Protein kinase A and hedgehog signaling in drosophila limb development

1995 • 310 citations

Proteolytic Processing Yields Two Secreted Forms of Sonic hedgehog

1995 • 309 citations

Products, genetic linkage and limb patterning activity of a murine hedgehog gene

1994 • 298 citations

HNF-3β as a regulator of floor plate development

1994 • 287 citations

Induction of floor plate differentiation by contact-dependent, homeogenetic signals

1993 • 271 citations

Cellular localization of tyrosine hydroxylase by immunohistochemistry.

1975 • 264 citations

cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in drosophila imaginal discs

1995 • 236 citations

Development of the brain stem in the rat. V. Thymidine‐radiographic study of the time of origin of neurons in the midbrain tegmentum

1981 • 232 citations

Control of neuronal diversity by the floor plate: Contact-mediated induction of midbrain dopaminergic neurons

1995 • 229 citations

Drosophila hedgehog acts as a morphogen in cellular patterning

1994 • 215 citations

Sequential expression of HNF-3β and HNF-3α by embryonic organizing centers: the dorsal lip/node, notochord and floor plate

1993 • 189 citations

Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation

1995 • 165 citations

Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning

1995 • 160 citations

Hedgehog and beyond

1995 • 149 citations

Regulation of furrow progression in the Drosophila eye by cAMP-dependent protein kinase A

1995 • 117 citations

The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin.

1994 • 111 citations

Isthmic origin of neurons of the rat substantia nigra

1983 • 101 citations

Floor plate-derived signals and the control of neural cell pattern in vertebrates.

1990 • 100 citations

Hedgehog, the floor plate, and the zone of polarizing activity

1994 • 71 citations

The role of Wnt genes in vertebrate development

1992 • 64 citations

Mutagenesis identifies amino-terminal residues of nerve growth factor necessary for Trk receptor binding and biological activity.

1994 • 58 citations