hnRNP A1 Recruited to an Exon In Vivo Can Function as an Exon Splicing Silencer

hnRNP PROTEINS AND THE BIOGENESIS OF mRNA

1993 • 1,486 citations

Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2

1992 • 724 citations

SR proteins and splicing control.

1996 • 668 citations

Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors

1994 • 612 citations

A three-hybrid system to detect RNA-protein interactions in vivo.

1996 • 499 citations

RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing.

1994 • 481 citations

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors.

1998 • 334 citations

A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.

1997 • 324 citations

Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins.

1994 • 321 citations

The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA

1993 • 309 citations

A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding.

1993 • 300 citations

General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer.

1993 • 286 citations

Transportin-mediated Nuclear Import of Heterogeneous Nuclear RNP Proteins

1997 • 252 citations

A Role for the M9 Transport Signal of hnRNP A1 in mRNA Nuclear Export

1997 • 249 citations

Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains.

1993 • 243 citations

Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF.

1993 • 241 citations

Trans-activation by HIV-1 Tat via a heterologous RNA binding protein

1990 • 236 citations

Mutation of PTB binding sites causes misregulation of alternative 3' splice site selection in vivo.

1997 • 233 citations

Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer.

1996 • 228 citations

The Polypyrimidine Tract Binding Protein Binds Upstream of Neural Cell-Specific c-src Exon N1 To Repress the Splicing of the Intron Downstream

1997 • 214 citations

The roles of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism

1996 • 205 citations

The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event.

1995 • 194 citations

The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo.

1994 • 186 citations

hnRNP A1 Selectively Interacts Through its Gly-rich Domain with Different RNA-binding Proteins

1996 • 179 citations

Presence of Exon Splicing Silencers within Human Immunodeficiency Virus Type 1 tat Exon 2 and tat-rev Exon 3: Evidence for Inhibition Mediated by Cellular Factors

1995 • 165 citations

Synergistic interactions between two distinct elements of a regulated splicing enhancer.

1995 • 156 citations

The mechanism of somatic inhibition of Drosophila P-element pre-mRNA splicing: multiprotein complexes at an exon pseudo-5' splice site control U1 snRNP binding.

1992 • 154 citations

RNA annealing activities in HeLa nuclei.

1994 • 148 citations

A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon

1994 • 144 citations

Heterogeneous nuclear ribonucleoprotein A1 binds to the transcription-regulatory region of mouse hepatitis virus RNA

1997 • 141 citations

Presence of Negative and Positive cis-Acting RNA Splicing Elements within and Flanking the First tat Coding Exon of Human Immunodeficiency Virus Type 1

1994 • 130 citations

Regulation of tissue-specific P-element pre-mRNA splicing requires the RNA-binding protein PSI.

1994 • 124 citations

An Intron Element Modulating 5′ Splice Site Selection in the hnRNP A1 Pre-mRNA Interacts with hnRNP A1

1997 • 123 citations

Soma-specific expression and cloning of PSI, a negative regulator of P element pre-mRNA splicing.

1995 • 118 citations

Exon and Intron Sequences, Respectively, Repress and Activate Splicing of a Fibroblast Growth Factor Receptor 2 Alternative Exon

1995 • 113 citations

Modulation of AUUUA Response Element Binding by Heterogeneous Nuclear Ribonucleoprotein A1 in Human T Lymphocytes

1997 • 111 citations

Sex-lethal Autoregulation Requires Multiple cis-Acting Elements Upstream and Downstream of the Male Exon and Appears to Depend Largely on Controlling the Use of the Male Exon 5′ Splice Site

1993 • 100 citations

Interaction of R17 coat protein with synthetic variants of its ribonucleic acid binding site

1983 • 93 citations

Control of BEK and K-SAM splice sites in alternative splicing of the fibroblast growth factor receptor 2 pre-mRNA.

1993 • 93 citations

Splicing efficiency of human immunodeficiency virus type 1 tat RNA is determined by both a suboptimal 3' splice site and a 10 nucleotide exon splicing silencer element located within tat exon 2

1997 • 92 citations

Multiple Interdependent Sequence Elements Control Splicing of a Fibroblast Growth Factor Receptor 2 Alternative Exon

1997 • 86 citations

A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer.

1996 • 82 citations

Mutations in the hrp48 Gene, Which Encodes a Drosophila Heterogeneous Nuclear Ribonucleoprotein Particle Protein, Cause Lethality and Developmental Defects and Affect P-Element Third-Intron Splicing In Vivo

1997 • 66 citations

The exon sequence TAGG can inhibit splicing

1996 • 66 citations

The alternative splicing factor PSI regulates P-element third intron splicing in vivo.

1997 • 64 citations

A naturally arising mutation of a potential silencer of exon splicing in human immunodeficiency virus type 1 induces dominant aberrant splicing and arrests virus production

1997 • 55 citations

Interaction of hnRNP A1 with snRNPs and pre-mRNAs: evidence for a possible role of A1 RNA annealing activity in the first steps of spliceosome assembly

1992 • 49 citations

Alternative Splicing of a Human α-Tropomyosin Muscle-Specific Exon: Identification of Determining Sequences

1992 • 47 citations

Novel Exonic Elements That Modulate Splicing of the Human Fibronectin EDA Exon

1997 • 42 citations

Specific binding of polypyrimidine tract binding protein and hnRNP A1 to HIV-1 CRS elements

1996 • 34 citations

SR Protein and snRNP Requirements for Assembly of the Rous Sarcoma Virus Negative Regulator of Splicing Complexin Vitro

1998 • 27 citations

Polypyrimidine tract-binding protein and heterogeneous nuclear ribonucleoprotein A1 bind to human T-cell leukemia virus type 2 RNA regulatory elements

1995 • 26 citations

A Crouzon Syndrome Synonymous Mutation Activates a 5′ Splice Site within the IIIC Exon of the FGFR2 Gene

1995 • 25 citations

Regulation of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) 2 gene transcript in neuronal cells

1998 • 17 citations

Tissue-specific splicing of two mutually exclusive exons of the chicken β-tropomyosin pre-mRNA: Positive and negative regulations

1996 • 11 citations