Chromatin Organization Contributes to Non-randomly Distributed Double-Strand Breaks after Exposure to High-LET Radiation

Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo

1999 • 2,380 citations

Biochemistry of DNA Lesions

1985 • 445 citations

A random-walk/giant-loop model for interphase chromosomes.

1995 • 306 citations

Evidence for the organization of chromatin in megabase pair-sized loops arranged along a random walk path in the human G0/G1 interphase nucleus.

1995 • 284 citations

Periodicity of DNA folding in higher order chromatin structures.

1990 • 275 citations

The Initial Physical Damage Produced by Ionizing Radiations

1989 • 255 citations

The size of chromatin loops in HeLa cells.

1990 • 246 citations

Non-random distribution of DNA double-strand breaks induced by particle irradiation

1996 • 230 citations

Clusters of DNA Damage Induced by Ionizing Radiation: Formation of Short DNA Fragments. II. Experimental Detection

1996 • 229 citations

A review of dsb induction data for varying quality radiations

1998 • 228 citations

Clusters of DNA induced by ionizing radiation: formation of short DNA fragments. I. Theoretical modeling.

1996 • 166 citations

Measurement of Prompt DNA Double-Strand Breaks in Mammalian Cells without Including Heat-Labile Sites: Results for Cells Deficient in Nonhomologous End Joining

2003 • 161 citations

DNA double-strand break distributions in X-ray and alpha-particle irradiated V79 cells: evidence for non-random breakage

1997 • 153 citations

In CHEF Electrophoresis a Linear Induction of Dsb Corresponds to a Nonlinear Fraction of Extracted DNA with Dose

1990 • 139 citations

DNA repair: Spot(light)s on chromatin

2001 • 131 citations

Clusters of DNA Damage Induced by Ionizing Radiation: Formation of Short DNA Fragments. I. Theoretical Modeling

1996 • 126 citations

DNA damage induced by radiation of different linear energy transfer: initial fragmentation

2000 • 124 citations

Chromatin conformation in living cells: support for a zig-zag model of the 30 nm chromatin fiber 1 1Edited by T. Richmond

1998 • 113 citations

The Influence of Chromatin Structure on the Frequency of Radiation-Induced DNA Strand Breaks: A Study Using Nuclear and Nucleoid Monolayers

1991 • 103 citations

Radiation-Induced Heat-Labile Sites that Convert into DNA Double-Strand Breaks

2000 • 98 citations

Rejoining of DNA fragments produced by radiations of different linear energy transfer

2000 • 98 citations

A domain model for eukaryotic DNA organization: A molecular basis for cell differentiation and chromosome evolution

1988 • 97 citations

DNA-Bound Proteins Contribute Much More Than Soluble Intracellular Compounds to the Intrinsic Protection against Radiation-Induced DNA Strand Breaks in Human Cells

1991 • 92 citations

Variation in Radiation-Induced Formation of DNA Double-Strand Breaks as a Function of Chromatin Structure

1992 • 81 citations

Chromatin Structure and Radiation-induced DNA Strand Breaks in Human Cells: Soluble Scavengers and DNA-bound Proteins Offer a Better Protection Against Single- than Double-strand Breaks

1995 • 73 citations

Nature of Lesions Formed by Ionizing Radiation

1998 • 69 citations

DNA Organization Affects Cellular Radiosensitivity and Detection of Initial DNA Strand Breaks

1992 • 68 citations

Radiation-induced DNA Damage and Chromatin Structure

2001 • 65 citations

Induction and Rejoining of DNA Double-Strand Breaks in Normal Human Skin Fibroblasts after Exposure to Radiation of Different Linear Energy Transfer: Possible Roles of Track Structure and Chromatin Organization

2001 • 64 citations

Differential Dependence on Chromatin Structure for Copper and Iron Ion Induction of DNA Double-Strand Breaks

1995 • 56 citations

Rejoining of DNA double-strand breaks induced by accelerated nitrogen ions

1996 • 56 citations

Nuclear Structure and the Microdistribution of Radiation Damage in DNA

1994 • 51 citations

No dose-dependence of DNA double-strand break misrejoining following α-particle irradiation

2000 • 50 citations

Induction of DNA Damage in γ-irradiated Nuclei Stripped of Nuclear Protein Classes: Differential Modulation of Double-strand Break and DNA—protein Crosslink Formation

1994 • 43 citations

Effects of Postirradiation Temperature on the Yields of Radiation-Induced Single- and Double-Strand Breakage in SV40 DNA

1994 • 39 citations

The role of higher-order chromatin structure in the yield and distribution of DNA double-strand breaks in cells irradiated with X-rays or α-particles

2000 • 39 citations

Quantification of radiation induced DNA double-strand breaks in human fibroblasts by PFGE: testing the applicability of random breakage models

2002 • 34 citations

Induction and Rejoining of Large DNA Fragments after Ion Irradiation

1999 • 23 citations

Influence of Irradiation Conditions on the Measurement of DNA Double-strand Breaks by Pulsed-field Gel Electrophoresis

1993 • 17 citations

The oxygen effect in permeabilized and histone-depleted cells: An enhanced OER for DNA double-strand breaks, compared to single-strand breaks, is abolished by soluble scavengers

1997 • 13 citations

Nuclear and Chromatin Structures and Their Influence on the Radiosensitivity of DNA

1994 • 12 citations

Radiation Quality Dependence of DNA Damage Induction

2002 • 6 citations

Nuclear and Chromatin Structures and Their Influence on the Radiosensitivity of DNA

1994 • 1 citations