The role of higher-order chromatin structure in the yield and distribution of DNA double-strand breaks in cells irradiated with X-rays or α-particles

The Role of DNA Single- and Double-Strand Breaks in Cell Killing by Ionizing Radiation

1998 • 322 citations

Non-random distribution of DNA double-strand breaks induced by particle irradiation

1996 • 230 citations

Clusters of DNA Damage Induced by Ionizing Radiation: Formation of Short DNA Fragments. II. Experimental Detection

1996 • 229 citations

A review of dsb induction data for varying quality radiations

1998 • 228 citations

Monte Carlo Simulation of the Production of Short DNA Fragments by Low-Linear Energy Transfer Radiation Using Higher-Order DNA Models

1998 • 168 citations

Clusters of DNA induced by ionizing radiation: formation of short DNA fragments. I. Theoretical modeling.

1996 • 166 citations

DNA double-strand break distributions in X-ray and alpha-particle irradiated V79 cells: evidence for non-random breakage

1997 • 153 citations

Toward A Unified Model Of Chromatin Folding

1989 • 139 citations

Chromatin conformation in living cells: support for a zig-zag model of the 30 nm chromatin fiber 1 1Edited by T. Richmond

1998 • 113 citations

The Influence of Chromatin Structure on the Frequency of Radiation-Induced DNA Strand Breaks: A Study Using Nuclear and Nucleoid Monolayers

1991 • 103 citations

Influence of chromatin structure on the induction of DNA double strand breaks by ionizing radiation.

1992 • 103 citations

DNA-Bound Proteins Contribute Much More Than Soluble Intracellular Compounds to the Intrinsic Protection against Radiation-Induced DNA Strand Breaks in Human Cells

1991 • 92 citations

Induction of DNA double-strand breaks by 1H and 4He lons in primary human skin fibroblasts in the LET range of 8 to 124 keV/microm.

1999 • 90 citations

Variation in Radiation-Induced Formation of DNA Double-Strand Breaks as a Function of Chromatin Structure

1992 • 81 citations

Genomic Instability in Chinese Hamster Cells after Exposure to X Rays or Alpha Particles of Different Mean Linear Energy Transfer

1997 • 74 citations

Gamma Radiation as a Probe of Chromatin Structure: Damage to and Repair of Active Chromatin in the Metaphase Chromosome

1984 • 73 citations

Chromatin Structure and Radiation-induced DNA Strand Breaks in Human Cells: Soluble Scavengers and DNA-bound Proteins Offer a Better Protection Against Single- than Double-strand Breaks

1995 • 73 citations

Induction of DNA Damage in γ-irradiated Nuclei Stripped of Nuclear Protein Classes: Differential Modulation of Double-strand Break and DNA—protein Crosslink Formation

1994 • 43 citations

The difference that linear energy transfer makes to precursors of DNA strand breaks.

1996 • 34 citations

Nuclear Thiols: Technical Limitations on the Determination of Endogenous Nuclear Glutathione and the Potential Importance of Sulfhydryl Proteins

1990 • 34 citations

DNA double-strand breaks in mammalian cells exposed to Á -rays and very heavy ions

1998 • 27 citations

Induction and Rejoining of Large DNA Fragments after Ion Irradiation

1999 • 23 citations

Quantification of DNA damage by PFGE: development of an analytical approach to correct for the background distribution

2000 • 19 citations

Induction of DNA double-strand breaks by ionizing radiation at the c- myc locus compared with the whole genome: a study using pulsed-field gel electrophoresis and gene probing

1996 • 18 citations

DNA double- and single-strand breaks induced by accelerated 2+ 6+ He and N ions in human cells: relative biological effectiveness is dependent on the relative contribution of the direct ands

1996 • 15 citations

Repair of clustered DNA damage caused by high LET radiation in human fibroblasts.

1998 • 14 citations

Application of Programmable, Autonomously Controlled Electrode (PACE) Technology to the Development of an Improved Pulsed Field Gel Electrophoresis Assay for DNA Double-strand Breaks in Mammalian Cells

1993 • 13 citations

Nuclear and Chromatin Structures and Their Influence on the Radiosensitivity of DNA

1994 • 12 citations

Differences between a human bladder carcinoma cell line and its radiosensitive clone in the formation of radiation-induced DNA double-strand breaks in different chromatin substrates

1998 • 5 citations

A study of DNA fragmentation patterns in cells irradiated with charged particles: evidence for non-random distributions.

1998 • 4 citations