A review of dsb induction data for varying quality radiations

A simple technique for quantitation of low levels of DNA damage in individual cells

1988 • 10,537 citations

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells

1984 • 1,672 citations

Reconstruction in vivo of Irradiated Escherichia coli Deoxyribonucleic Acid; the Rejoining of Broken Pieces

1966 • 727 citations

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

1979 • 577 citations

The native, denatured and renatured states of deoxyribonucleic acid

1965 • 546 citations

DNA double-strand breaks measured in individual cells subjected to gel electrophoresis.

1991 • 330 citations

The Level of Induced DNA Double-strand Breakage Correlates with Cell Killing after X-irradiation

1985 • 316 citations

Evidence for DNA Double-Strand Breaks as the Critical Lesions in Yeast Cells Irradiated with Sparsely or Densely Ionizing Radiation under Oxic or Anoxic Conditions

1981 • 271 citations

Theory of Depolymerization of Long Chain Molecules

1940 • 269 citations

Non-random distribution of DNA double-strand breaks induced by particle irradiation

1996 • 230 citations

Clusters of DNA Damage Induced by Ionizing Radiation: Formation of Short DNA Fragments. II. Experimental Detection

1996 • 229 citations

Separation of very large DNA molecules by gel electrophoresis

1978 • 199 citations

Alkaline elution analysis, a new approach to the study of DNA single-strand interruptions in cells.

1973 • 197 citations

Induction and Rejoining of DNA Double-strand Breaks in V79-4 Mammalian Cells Following γ- and α-irradiation

1993 • 186 citations

Sedimentation Coefficients of Linear and Cyclic Wormlike Coils with Excluded-Volume Effects

1967 • 185 citations

DNA Double-strand Break Repair Determines the RBE of α-particles

1988 • 172 citations

Radiation-induced Single-strand Breaks in DNA Determined by Rate of Alkaline Strand Separation and Hydroxylapatite Chromatography: An Alternative to Velocity Sedimentation

1974 • 168 citations

DNA double-strand break distributions in X-ray and alpha-particle irradiated V79 cells: evidence for non-random breakage

1997 • 153 citations

In CHEF Electrophoresis a Linear Induction of Dsb Corresponds to a Nonlinear Fraction of Extracted DNA with Dose

1990 • 139 citations

Double-strand breaks in the DNA of a mammalian cell after X-irradiation

1970 • 128 citations

DNA Double Strand Breaks in Ehrlich Ascites Tumour Cells at Low Doses of X-rays. I. Determination of Induced Breaks by Centrifugation at Reduced Speed

1982 • 123 citations

Rejoining of Double Strand Breaks in Normal Human and Ataxia-telangiectasia Fibroblasts after Exposure to⁶⁰Co γ-rays,²⁴¹Am α-particles or Bleomycin

1987 • 117 citations

The Relationship between Radiation-induced DNA Double-strand Breaks and Cell Kill in Hamster V79 Fibroblasts Irradiated with 250 kVp X-rays, 2·3 MeV Neutrons or²³⁸Pu α-particles

1987 • 116 citations

Induction and Rejoining of DNA Double-Strand Breaks in Chinese Hamster V79-4 Cells Irradiated with Characteristic Aluminum K and Copper L Ultrasoft X Rays

1997 • 103 citations

¹²⁵I-induced DNA Double Strand Breaks: Use in Calibration of the Neutral Filter Elution Technique and Comparison with X-ray Induced Breaks

1985 • 99 citations

Effectiveness of 1·5 keV Aluminium K and 0·3 keV Carbon K Characteristic X-rays at Inducing DNA Double-strand Breaks in Yeast Cells

1986 • 98 citations

DNA Double-Strand Breaks Induced by High-Energy Neon and Iron Ions in Human Fibroblasts. I. Pulsed-Field Gel Electrophoresis Method

1994 • 96 citations

Anomalies in sedimentation

1974 • 95 citations

Methods for the Quantification of DNA Double-Strand Breaks Determined from the Distribution of DNA Fragment Sizes Measured by Pulsed-Field Gel Electrophoresis

1995 • 92 citations

Detection of DNA single-strand breaks produced during the repair of damage by DNA-protein cross-linking agents.

1982 • 90 citations

The Irradiation of V79 Mammalian Cells by Protons with Energies below 2 MeV. Part II. Measurement of Oxygen Enhancement Ratios and DNA Damage

1990 • 88 citations

Lethality of Heavy Ion-induced DNA Double-strand Breaks in Mammalian Cells

1993 • 84 citations

Linear DNA Elution Dose Response Curves Obtained in CHO Cells with Non-unwinding Filter Elution after Appropriate Selection of the Lysis Conditions

1989 • 84 citations

Relative Contributions of Levels of Initial DNA Damage and Repair of Double Strand Breaks to the Ionizing Radiation-sensitive Phenotype of the Chinese Hamster Cell Mutant, XR-V15B. Part I. X-rays

1993 • 82 citations

Comparison between Pulsed-field and Constant-field Gel Electrophoresis for Measurement of DNA Double-strand Breaks in Irradiated Chinese Hamster Ovary Cells

1991 • 78 citations

Double Strand Rejoining in Mammalian DNA

1973 • 69 citations

Direct Comparison of Biological Effectiveness of Protons and Alpha-particles of the Same LET. III. Initial Yield of DNA Double-strand Breaks in V79 Cells

1992 • 67 citations

DNA strand break rejoining defect in xrs-6 is complemented by transfection with the human Ku80 gene.

1995 • 59 citations

Rejoining of DNA double-strand breaks induced by accelerated nitrogen ions

1996 • 56 citations

DNA-protein crosslinking by trans-platinum(II)diamminedichloride in mammalian cells, a new method of analysis

1979 • 53 citations

A Quantitative Model of DNA Fragments Generated by Ionizing Radiation, and Possible Experimental Applications

1991 • 53 citations

Clonogenic Cell Survival and Rejoining of DNA Double-strand Breaks: Comparisons between Three Cell Lines after Photon or He Ion Irradiation

1994 • 52 citations

DNA Double-Strand Breaks Induced by High-Energy Neon and Iron Ions in Human Fibroblasts. II. Probing Individual NotI Fragments by Hybridization

1994 • 51 citations

Direct Comparison of Biological Effectiveness of Protons and Alpha-particles of the Same LET. II. Mutation Induction at the HPRT Locus in V79 Cells

1992 • 51 citations

Induction of DNA Double-strand Breaks in CHO-K1 Cells by Carbon Ions

1995 • 47 citations

Measurement of DNA Damage and Cell Killing in Chinese Hamster V79 Cells Irradiated with Aluminum Characteristic Ultrasoft X Rays

1989 • 43 citations

DNA Double-strand Break Measurement in Mammalian Cells by Pulsed-field Gel Electrophoresis: An Approach Using Restriction Enzymes and Gene Probing

1994 • 41 citations

Physical Basis for Detection of DNA Double-Strand Breaks Using Neutral Filter Elution

1990 • 40 citations

Heavy Ion-induced DNA Double-strand Breaks in Yeast

1992 • 40 citations

Randomly distributed DNA double-strand breaks as measured by pulsed field gel electrophoresis: A series of explanatory calculations

1994 • 37 citations

Measurement of DNA Double-Strand Breaks in Mammalian Cells by Pulsed-Field Gel Electrophoresis: A New Approach Using Rarely Cutting Restriction Enzymes

1994 • 36 citations

A rotor speed dependent crossover in sedimentation velocities of DNA's of different sizes

1974 • 33 citations

DNA Double-strand Breaks Induced by Low Energy Protons in V79 Cells

1994 • 33 citations

An assay for quantifying DNA double-strand break repair that is suitable for small numbers of unlabeled cells.

1997 • 32 citations

The Rejoining of DNA Double-strand Breaks Following Irradiation with²³⁸Pu α-particles: Evidence for a Fast Component of Repair as Measured by Neutral Filter Elution

1990 • 30 citations

The distribution of radioactive recovery in randomly cut and sedimented DNA

1969 • 30 citations

Single-cell Gel Technique Supports Hit Probability Calculations

1993 • 28 citations

The organization and repair of mammalian DNA

1974 • 28 citations

DNA Double-strand Break Induction in Yeast by X-rays and α-particles Measured by Pulsed-field Gel Electrophoresis

1993 • 28 citations

Relative Contributions of Levels of Initial Damage and Repair of Double-strand Breaks to the Ionizing Radiation-sensitive Phenotype of the Chinese Hamster Cell Mutant, XR-V15B. Part II. Neutrons

1993 • 26 citations

Separation of DNA Fragments Induced by Ionizing Irradiation Using a Graded-field Gel Electrophoresis

1995 • 25 citations

Comet assay study of DNA damage and repair of tumour cells following boron neutron capture irradiation with fast d 14 Be neutrons

1996 • 25 citations

An Assay for Quantifying DNA Double-Strand Break Repair That Is Suitable for Small Numbers of Unlabeled Cells

1997 • 24 citations

Determination of Radiation-induced DNA Strand Breaks in Individual Cells by Non-radioactive Labelling of 3′ OH Ends

1995 • 23 citations

Double Strand Breaks Induced by Low Doses of γ Rays or Heavy Ions: Quantitation in Nonradioactive Human DNA

1996 • 20 citations

The sucrose gradient and native DNA s20,w, an examination of measurement problems

1976 • 20 citations

The Analysis of Single-strand Breaks inE. ColiUsing a Curve-fitting Procedure

1976 • 19 citations

Induction of DNA double-strand breaks by ionizing radiation at the c- myc locus compared with the whole genome: a study using pulsed-field gel electrophoresis and gene probing

1996 • 18 citations

Heavy ion-induced DNA double-strand breaks with yeast as a model system

1995 • 17 citations

Size Distribution of DNA Molecules Recovered from Non-denaturing Filter Elution

1991 • 16 citations

DNA double- and single-strand breaks induced by accelerated 2+ 6+ He and N ions in human cells: relative biological effectiveness is dependent on the relative contribution of the direct ands

1996 • 15 citations

Dependence of the sedimentation of high molecular weight DNA on centrifuge speed

1976 • 15 citations

A quantitative test of Zimm's model for the rotor‐speed‐department sedimentation of linear DNA molecules

1980 • 15 citations

DNA DOUBLE-STRAND BREAKS DETECTED IN INDIVIDUAL CELLS

1991 • 14 citations

Radiation-Induced Damage in Chromosomal DNA Molecules: Deduction of Chromosomal DNA Organization from the Hydrodynamic Data Used to Measure DNA Double-Strand Breaks and from Stereo Electron Microscopic Observations

1993 • 13 citations

The organization and repair of DNA in the mammalian chromosome. I. Calibration procedures and errors in the determination of the molecular weight of a native DNA

1977 • 12 citations

Investigation of the Neutral Filter Elution Technique: I. Effects of Pore Density and Pore Diameter on Elution Rate at pH 9.6

1991 • 8 citations

The Filter Does Not Act as a DNA Size Discriminator in the Neutral Filter Elution Technique

1992 • 6 citations