Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

Altering the Genome by Homologous Recombination

1989 • 2,021 citations

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

1990 • 1,531 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

Epithelial-Mesenchymal Interactions

1967 • 1,218 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

The murine and Drosophila homeobox gene complexes have common features of organization and expression

1989 • 1,021 citations

The structure and function of the homeodomain

1989 • 1,007 citations

Trans-complementable copy-number mutants of plasmid ColE1

1980 • 975 citations

The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.

1989 • 912 citations

Homeo Boxes in the Study of Development

1987 • 905 citations

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

1990 • 896 citations

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1991 • 856 citations

The role of the neural crest in patterning of avian cranial skeletal, connective, and muscle tissues

1983 • 852 citations

Segmental patterns of neuronal development in the chick hindbrain

1989 • 840 citations

Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain

1989 • 566 citations

The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene

1980 • 556 citations

Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse

1989 • 511 citations

Interactions and fates of avian craniofacial mesenchyme

1988 • 492 citations

Hox and HOM: Homologous gene clusters in insects and vertebrates

1989 • 467 citations

Transgenesis by means of blastocyst-derived embryonic stem cell lines.

1986 • 432 citations

Subtle Cerebellar Phenotype in Mice Homozygous for a Targeted Deletion of the En-2 Homeobox

1991 • 416 citations

The house mouse. Development and normal stages from fertilization to 4 weeks of age.

1972 • 413 citations

Variations of cervical vertebrate after expression of a Hox-1.1 transgene in mice

1990 • 371 citations

The embryonic development of mammalian neural tube defects

1990 • 337 citations

Expression of homeo box genes during mouse development: a review.

1988 • 331 citations

Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm

1990 • 300 citations

Analysis of the developmental effects of a lethal mutation in the house mouse

1954 • 290 citations

Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid

1973 • 287 citations

Teratocarcinomas and Embryonic Stem Cells: A Practical Approach

1988 • 263 citations

Patterning the vertebrate head: murine Hox 2 genes mark distinct subpopulations of premigratory and migrating cranial neural crest

1991 • 246 citations

Expression of the mouse labial-Alike homeobox-containing genes, Hox 2.9 and Hox 1.6, during segmentation of the hindbrain

1991 • 239 citations

Cooperativity and hierarchical levels of functional organization in the SV40 enhancer

1988 • 238 citations

Early retinoic acid-induced F9 teratocarcinoma stem cell gene ERA-1: alternate splicing creates transcripts for a homeobox-containing protein and one lacking the homeobox.

1988 • 219 citations

Segment-specific expression of a homoeobox-containing gene in the mouse hindbrain

1989 • 214 citations

Segmentation and the origin of regional diversity in the vertebrate central nervous system

1990 • 208 citations

Spatial restriction in expression of a mouse homoeo box locus within the central nervous system

1986 • 203 citations

Neural crest formation in the head of the mouse embryo as observed using a new histological technique

1981 • 201 citations

Head morphogenesis in embryonic avian chimeras: evidence for a segmental pattern in the ectoderm corresponding to the neuromeres

1990 • 200 citations

Mouse homeobox gene transcripts occupy different but overlapping domains in embryonic germ layers and organs: a comparison of Hox-3.1 and Hox-1.5

1988 • 152 citations

Are cross-regulatory interactions between homoeotic genes functionally significant?

1990 • 148 citations

Homoeobox gene Hox-1.5 expression in mouse embryos: earliest detection by in situ hybridization is during gastrulation

1987 • 137 citations

Isolation, structure, and expression of labial, a homeotic gene of the Antennapedia Complex involved in Drosophila head development.

1989 • 132 citations

Homeobox genes and models for patterning the hindbrain and branchial arches

1991 • 130 citations

Plasmid and bacteriophage vectors for excision of intact inserts

1987 • 127 citations

Homoeobox gene expression in mouse embryos varies with position by the primitive streak stage

1986 • 126 citations

Hox-1.6: a mouse homeo-box-containing gene member of the Hox-1 complex.

1987 • 119 citations

Patterning in the vertebrate limb

1991 • 114 citations

Region-specific expression in early chick and mouse embryos of Ghox-lab and Hox 1.6, vertebrate homeobox-containing genes related to Drosophila labial

1990 • 108 citations

Cephalic Neural Crest and Placodes

1979 • 105 citations

Molecular structure and spatial expression of a homeobox gene from the labial region of the Antennapedia-complex.

1988 • 104 citations

Sequence analysis of the murine Hox-2.2, −2.3, and −2.4 homeo boxes: Evolutionary and structural comparisons

1987 • 91 citations

Anterior boundaries of Hox gene expression in mesoderm-derived structures correlate with the linear gene order along the chromosome

1989 • 91 citations

Overexpression of a homeodomain protein confers axis-forming activity to uncommitted xenopus embryonic cells

1991 • 88 citations

Cephalic ectodermal placodes and neurogenesis

1986 • 85 citations

Developmental relationships between trigeminal ganglia and trigeminal motoneurons in chick embryos. II. Ganglion axon ingrowth guides motoneuron migration

1983 • 68 citations

Influence of the Neural Tube on the Differentiation of the Inner Ear in the Mammalian Embryo

1966 • 62 citations

Mapping cranial neural crest cell migration pathways in mammalian embryos

1987 • 59 citations

An embryonic pineal body as a multipotent system in cell differentiation.

1988 • 43 citations

Tissue interactions and cell differentiation: neurone-sensory cell interaction during otic development

1988 • 38 citations

From gradients to axes, from morphogenesis to differentiation

1990 • 36 citations

Isolation and regional localization of the murine homeobox-containing gene Hox-3.3 to mouse chromosome region 15E

1989 • 30 citations

Homeobox genes and the vertebrate head

1988 • 26 citations

The murine genes Hox-5.1 and Hox-4.1 belong to the same HOX complex on chromosome 2

1990 • 23 citations

Gene organization of murine homeobox-containing gene clusters

1988 • 21 citations

The homeobox in vertebrate development

1989 • 20 citations