Fc receptor endocytosis is controlled by a cytoplasmic domain determinant that actively prevents coated pit localization.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

A new method of preparing gold probes for multiple-labeling cytochemistry.

1985 • 1,417 citations

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

Fc Receptors

1991 • 1,220 citations

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

1990 • 944 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition.

1984 • 545 citations

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

1990 • 508 citations

Ankyrin binding to (Na+ + K+)ATPase and implications for the organization of membrane domains in polarized cells

1987 • 470 citations

Toxoplasma gondii : Fusion Competence of Parasitophorous Vacuoles in Fc Receptor-Transfected Fibroblasts

1990 • 446 citations

Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity

1990 • 444 citations

Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

1989 • 356 citations

The low density lipoprotein receptor. Identification of amino acids in cytoplasmic domain required for rapid endocytosis.

1987 • 355 citations

Structural Heterogeneity and Functional Domains of Murine Immunoglobulin G Fc Receptors

1986 • 343 citations

Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization.

1990 • 312 citations

Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes.

1989 • 300 citations

Cross-linking of B lymphocyte Fc gamma receptors and membrane immunoglobulin inhibits anti-immunoglobulin-induced blastogenesis.

1984 • 292 citations

Organization of the Human and Mouse Low-affinity FcγR Genes: Duplication and Recombination

1990 • 290 citations

Ankyrin links fodrin to the alpha subunit of Na,K-ATPase in Madin-Darby canine kidney cells and in intact renal tubule cells.

1989 • 276 citations

Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis

1989 • 272 citations

Fc receptor isoforms exhibit distinct abilities for coated pit localization as a result of cytoplasmic domain heterogeneity

1989 • 259 citations

Internalization and degradation of macrophage Fc receptors bound to polyvalent immune complexes.

1984 • 250 citations

A single amino acid change in the cytoplasmic domain allows the influenza virus hemagglutinin to be endocytosed through coated pits

1988 • 245 citations

Surface distribution and recycling of the low density lipoprotein receptor as visualized with antireceptor antibodies.

1982 • 240 citations

Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins.

1990 • 199 citations

Crosslinking of surface immunoglobulin and Fc receptors on B lymphocytes inhibits stimulation of inositol phospholipid breakdown via the antigen receptors.

1985 • 198 citations

Purificaton of a functional mouse Fc receptor through the use of a monoclonal antibody.

1980 • 173 citations

Expression of a recombinant DNA gene coding for the vesicular stomatitis virus nucleocapsid protein

1983 • 170 citations

A complementary DNA clone for a macrophage-lymphocyte Fc receptor

1986 • 169 citations

Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.

1989 • 159 citations

Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII).

1987 • 150 citations

Transport of macrophage Fc receptors and Fc receptor-bound ligands to lysosomes.

1986 • 149 citations

Isolation of cDNAs for two distinct human Fc receptors by ligand affinity cloning.

1988 • 148 citations

Human transferrin receptor internalization is partially dependent upon an aromatic amino acid on the cytoplasmic domain.

1990 • 130 citations

Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domain.

1990 • 121 citations

Deletions in the cytoplasmic domain of the polymeric immunoglobulin receptor differentially affect endocytotic rate and postendocytotic traffic.

1990 • 100 citations

Incorporation of a charged amino acid into the membrane-spanning domain blocks cell surface transport but not membrane anchoring of a viral glycoprotein.

1985 • 93 citations

Co-capping of ras proteins with surface immunoglobulins in B lymphocytes

1990 • 81 citations

The murine Fc receptor for immunoglobulin: purification, partial amino acid sequence, and isolation of cDNA clones.

1986 • 78 citations

Relationships between structure and function in the Fc receptor family

1988 • 64 citations

Endocytosis of the ASGP receptor H1 is reduced by mutation of tyrosine-5 but still occurs via coated pits.

1991 • 62 citations

Fc receptor phosphorylation during receptor-mediated control of B-cell activation

1990 • 48 citations

A point mutation in the cytoplasmic domain of the transferrin receptor inhibits endocytosis

1990 • 43 citations

Incorporation of a Charged Amino Acid into the Membrane-Spanning Domain Blocks Cell Surface Transport But Not Membrane Anchoring of a Viral Glycoprotein

1985 • 41 citations

Endocytosis of antigen, anti-idiotype, and anti-immunoglobulin antibodies and receptor re-expression by murine B cells.

1989 • 30 citations