The cytoplasmic domain of P-selectin contains a sorting determinant that mediates rapid degradation in lysosomes

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

1985 • 1,585 citations

The Biogenesis of Lysosomes

1989 • 1,583 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Selectins: Interpreters of Cell-Specific Carbohydrate Information During Inflammation

1992 • 1,255 citations

Pathways of Protein Secretion in Eukaryotes

1985 • 1,050 citations

Biochemistry of dystrophic muscle. Mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase

1961 • 1,041 citations

Rapid neutrophil adhesion to activated endothelium mediated by GMP-140

1990 • 997 citations

GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies.

1989 • 993 citations

Selectins.

1993 • 869 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Cloning of GMP-140, a granule membrane protein of platelets and endothelium: Sequence similarity to proteins involved in cell adhesion and inflammation

1989 • 799 citations

Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140

1989 • 653 citations

Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells.

1983 • 636 citations

Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils.

1991 • 600 citations

A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

1992 • 540 citations

Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.

1992 • 519 citations

Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process.

1993 • 516 citations

Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body

1990 • 452 citations

Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line.

1988 • 381 citations

Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor-mediated endocytosis and the genetics of familial hypercholesterolemia.

1981 • 359 citations

Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38)

1990 • 355 citations

Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome.

1989 • 330 citations

Endocytosis of growth factor receptors

1993 • 277 citations

Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail.

1990 • 272 citations

A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin.

1991 • 257 citations

Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane

1992 • 252 citations

Internalization and degradation of macrophage Fc receptors bound to polyvalent immune complexes.

1984 • 250 citations

Leukocyte—endothelial cell interactions

1992 • 246 citations

Surface distribution and recycling of the low density lipoprotein receptor as visualized with antireceptor antibodies.

1982 • 240 citations

Intracellular movement of cell surface receptors after endocytosis: resialylation of asialo-transferrin receptor in human erythroleukemia cells.

1985 • 229 citations

The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the Golgi.

1992 • 225 citations

Endocytosis and signals for internalization

1991 • 209 citations

A His-Leu-Leu sequence near the carboxyl terminus of the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor is necessary for the lysosomal enzyme sorting function.

1992 • 205 citations

Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins.

1987 • 197 citations

Lysosomal acid phosphatase is transported to lysosomes via the cell surface.

1989 • 189 citations

Targeting of a lysosomal membrane protein: a tyrosine-containing endocytosis signal in the cytoplasmic tail of lysosomal acid phosphatase is necessary and sufficient for targeting to lysosomes.

1990 • 185 citations

Biosynthesis and turnover of the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.

1983 • 169 citations

Cytoplasmic domain of P-selectin (CD62) contains the signal for sorting into the regulated secretory pathway.

1992 • 156 citations

Low density lipoprotein receptor and cation-independent mannose 6-phosphate receptor are transported from the cell surface to the Golgi apparatus at equal rates in PC12 cells

1992 • 147 citations

Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells.

1990 • 144 citations

Identification of a novel sequence mediating regulated endocytosis of the G protein-coupled alpha-pheromone receptor in yeast.

1993 • 126 citations

P-selectin, a granule membrane protein of platelets and endothelial cells, follows the regulated secretory pathway in AtT-20 cells.

1992 • 120 citations

Phosphorylation-dependent down-modulation of CD4 requires a specific structure within the cytoplasmic domain of CD4

1991 • 120 citations

First cysteine-rich repeat in ligand-binding domain of low density lipoprotein receptor binds Ca2+ and monoclonal antibodies, but not lipoproteins.

1987 • 115 citations

Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells.

1989 • 114 citations

Structural and Biosynthetic Studies of the Granule Membrane Protein, GMP-140, from Human Platelets and Endothelial Cells

1989 • 107 citations

Antibody to mannose 6-phosphate specific receptor induces receptor deficiency in human fibroblasts.

1984 • 104 citations

Recycling of epidermal growth factor-receptor complexes in A431 cells: identification of dual pathways.

1991 • 102 citations

Leukocyte Interactions Mediated by P-Selection

1993 • 100 citations

DYNAMICS OF CYTOPLASMIC MEMBRANES IN GUINEA PIG PANCREATIC ACINAR CELLS

1974 • 90 citations

Efficient Transfection and Expression of Heterologous Genes in PC12 Cells

1990 • 78 citations

Sequential processing of lysosomal acid phosphatase by a cytoplasmic thiol proteinase and a lysosomal aspartyl proteinase.

1989 • 76 citations

Monoclonal antibodies against defined epitopes of the human transferrin receptor cytoplasmic tail

1992 • 69 citations

A kinetic analysis of biosynthesis and localization of a lysosome-associated membrane glycoprotein

1986 • 61 citations

Murine endothelial leukocyte‐adhesion molecule 1 is a close structral and functional homologue of the human protein

1992 • 55 citations

The Control of Membrane Traffic on the Endocytic Pathway

1987 • 35 citations

Characterization of pinocytic vesicles from CHO cells: Resolution of pinosomes from lysosomes by analytical centrifugation

1983 • 34 citations

Endocytic membrane traffic to the Golgi apparatus in a regulated secretory cell line.

1990 • 30 citations

Phosphorylation of surface E‐selectin and the effect of soluble ligand (Sialyl Lewis^x) on the half‐life of E‐selectin

1993 • 28 citations

Sterol-mediated regulation of mevalonic acid synthesis. Accumulation of 4-carboxysterols as the predominant sterols synthesized in a Chinese hamster ovary cell cholesterol auxotroph (mutant 215).

1990 • 23 citations

The cytoplasmic tail of CD4 targets chimeric molecules to a degradative pathway.

1991 • 4 citations

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