Mannose 6-Phosphate Receptors and ADP-ribosylation Factors Cooperate for High Affinity Interaction of the AP-1 Golgi Assembly Proteins with Membranes

The Biogenesis of Lysosomes

1989 • 1,583 citations

STRUCTURE AND FUNCTION OF THE MANNOSE 6-PHOSPHATE/INSULINLIKE GROWTH FACTOR II RECEPTORS

1992 • 1,056 citations

Molecular dissection of the secretory pathway

1992 • 985 citations

Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat.

1991 • 874 citations

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

1994 • 793 citations

Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

1992 • 741 citations

Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF

1992 • 736 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding protein

1991 • 604 citations

Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs

1994 • 574 citations

Synaptotagmin I is a high affinity receptor for clathrin AP-2: Implications for membrane recycling

1994 • 483 citations

Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae

1991 • 465 citations

ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranes.

1992 • 464 citations

A Regulatory Role for ARF6 in Receptor-Mediated Endocytosis

1995 • 451 citations

The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein

1993 • 422 citations

Dominant inhibitory mutants of ARF1 block endoplasmic reticulum to Golgi transport and trigger disassembly of the Golgi apparatus.

1994 • 418 citations

Receptors compete for adaptors found in plasma membrane coated pits.

1988 • 366 citations

Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments.

1995 • 365 citations

Recruitment of coat proteins onto Golgi membranes in intact and permeabilized cells: Effects of brefeldin A and G protein activators

1992 • 358 citations

Structural relationships between clathrin assembly proteins from the Golgi and the plasma membrane.

1988 • 356 citations

Mapping the distribution of Golgi enzymes involved in the construction of complex oligosaccharides

1995 • 350 citations

The role of clathrin, adaptors and dynamin in endocytosis

1994 • 343 citations

Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor.

1989 • 336 citations

Binding of coatomer to Golgi membranes requires ADP-ribosylation factor

1993 • 334 citations

Biochemical dissection of AP-1 recruitment onto Golgi membranes.

1993 • 308 citations

Transcription occurs at a nucleoskeleton.

1985 • 303 citations

Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles.

1993 • 278 citations

100-kD coated vesicle proteins: molecular heterogeneity and intracellular distribution studied with monoclonal antibodies

1987 • 234 citations

Purification and properties of 100-kd proteins from coated vesicles and their reconstitution with clathrin.

1984 • 229 citations

ADP-ribosylation factor is required for vesicular trafficking between the endoplasmic reticulum and the cis-Golgi compartment.

1992 • 213 citations

Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells.

1991 • 207 citations

Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins

1991 • 199 citations

Expression of a dominant allele of human ARF1 inhibits membrane traffic in vivo

1994 • 190 citations

Multiple GTP-binding proteins participate in clathrin-coated vesicle-mediated endocytosis.

1993 • 188 citations

Evidence for ADP-ribosylation factor (ARF) as a regulator of in vitro endosome-endosome fusion.

1992 • 185 citations

A Casein Kinase II Phosphorylation Site in the Cytoplasmic Domain of the Cation-dependent Mannose 6-Phosphate Receptor Determines the High Affinity Interaction of the AP-1 Golgi Assembly Proteins with Membranes

1996 • 173 citations

Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins).

1989 • 157 citations

The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly components.

1993 • 157 citations

Differential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts.

1994 • 145 citations

Fine Structure Immunocytochemistry

1994 • 139 citations

Cloning and expression of gamma-adaptin, a component of clathrin-coated vesicles associated with the Golgi apparatus.

1990 • 138 citations

Structural and functional division into two domains of the large (100- to 115-kDa) chains of the clathrin-associated protein complex AP-2.

1989 • 131 citations

Two distinct members of the ADP-ribosylation factor family of GTP-binding proteins regulate cell-free intra-golgi transport

1992 • 128 citations

Identification of a clathrin binding subunit in the HA2 adaptor protein complex

1989 • 122 citations

Two distinct populations of ARF bound to Golgi membranes.

1993 • 118 citations

In vitro binding of plasma membrane-coated vesicle adaptors to the cytoplasmic domain of lysosomal acid phosphatase

1993 • 114 citations

100-kD proteins of Golgi- and trans-Golgi network-associated coated vesicles have related but distinct membrane binding properties

1992 • 109 citations

Molecular recognition and targeting of lysosomal proteins

1991 • 105 citations

Different Domains of the AP-1 Adaptor Complex Are Required for Golgi Membrane Binding and Clathrin Recruitment

1995 • 104 citations

Adaptor self-aggregation, adaptor-receptor recognition and binding of alpha-adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits.

1993 • 102 citations

In vitro binding of the asialoglycoprotein receptor to the beta adaptin of plasma membrane coated vesicles.

1991 • 102 citations

Binding of AP-1 Golgi adaptors to membranes requires phosphorylated cytoplasmic domains of the mannose 6-phosphate/insulin-like growth factor II receptor.

1993 • 101 citations

Conservation and diversity in families of coated vesicle adaptins.

1990 • 94 citations

Targeting and mistargeting of plasma membrane adaptors in vitro.

1993 • 92 citations

Adaptins

1992 • 89 citations

Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial missorting of multiple lysosomal enzymes.

1993 • 86 citations

Phosphorylation of the cytoplasmic domain of the bovine cation-independent mannose 6-phosphate receptor. Serines 2421 and 2492 are the targets of a casein kinase II associated to the Golgi-derived HAI adaptor complex.

1990 • 86 citations

Phosphorylation of the cation-independent mannose 6-phosphate receptor is closely associated with its exit from the trans-Golgi network.

1993 • 85 citations

The appendage domain of the AP-2 subunit is not required for assembly or invagination of clathrin-coated pits.

1993 • 75 citations

Clathrin-coated vesicles

1989 • 69 citations

Phosphorylation of the human 46-kDa mannose 6-phosphate receptor in the cytoplasmic domain at serine 56

1993 • 32 citations