Distinct signals in the GLUT4 glucose transporter for internalization and for targeting to an insulin-responsive compartment.

Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat.

1991 • 874 citations

Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-dependent Concentration of Urine

1994 • 870 citations

Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells.

1978 • 678 citations

Identification of a novel gene encoding an insulin-responsive glucose transporter protein

1989 • 601 citations

Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein.

1986 • 550 citations

Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes

1994 • 442 citations

Isolation and characterization of the intracellular MHC class II compartment

1994 • 426 citations

Translocation of the glucose transporter GLUT4 in cardiac myocytes of the rat.

1991 • 398 citations

Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells

1994 • 349 citations

Cell surface labeling of glucose transporter isoform GLUT4 by bis-mannose photolabel. Correlation with stimulation of glucose transport in rat adipose cells by insulin and phorbol ester.

1990 • 325 citations

Translocation of the glucose transporter (GLUT4) to the cell surface in permeabilized 3T3-L1 adipocytes: effects of ATP insulin, and GTP gamma S and localization of GLUT4 to clathrin lattices

1992 • 307 citations

Targeting of membrane proteins to endosomes and lysosomes

1994 • 304 citations

Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action.

1993 • 297 citations

Members of the VAMP family of synaptic vesicle proteins are components of glucose transporter-containing vesicles from rat adipocytes.

1992 • 275 citations

Differential sorting of two glucose transporters expressed in insulin-sensitive cells

1991 • 258 citations

Comparison of GLUT4 and GLUT1 subcellular trafficking in basal and insulin-stimulated 3T3-L1 cells.

1993 • 252 citations

Insulin regulation of the two glucose transporters in 3T3-L1 adipocytes.

1990 • 236 citations

Effects of insulin on steady state kinetics of GLUT4 subcellular distribution in rat adipocytes. Evidence of constitutive GLUT4 recycling.

1992 • 225 citations

Cloning of a Rab3 isotype predominantly expressed in adipocytes.

1992 • 203 citations

Insulin-stimulated GLUT4 glucose transporter recycling. A problem in membrane protein subcellular trafficking through multiple pools

1994 • 164 citations

Immunoelectron microscopic demonstration of insulin-stimulated translocation of glucose transporters to the plasma membrane of isolated rat adipocytes and masking of the carboxyl-terminal epitope of intracellular GLUT4.

1991 • 162 citations

Direct demonstration of insulin-induced GLUT4 translocation to the surface of intact cells by insertion of a c-myc epitope into an exofacial GLUT4 domain

1993 • 156 citations

Intracellular targeting of the insulin-regulatable glucose transporter (GLUT4) is isoform specific and independent of cell type.

1991 • 141 citations

Insulin and nonhydrolyzable GTP analogs induce translocation of GLUT 4 to the plasma membrane in alpha-toxin-permeabilized rat adipose cells

1991 • 139 citations

The Acquisition of Increased Insulin-responsive Hexose Transport in 3T3-L1 Adipocytes Correlates with Expression of a Novel Transporter Gene

1989 • 137 citations

The Insulin-Sensitive Glucose Transporter

1992 • 135 citations

The efficient intracellular sequestration of the insulin-regulatable glucose transporter (GLUT-4) is conferred by the NH2 terminus

1992 • 121 citations

The glucose transporter GluT4 and secretory carrier membrane proteins (SCAMPs) colocalize in rat adipocytes and partially segregate during insulin stimulation.

1993 • 121 citations

GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration.

1993 • 118 citations

A Leu-Leu sequence is essential for COOH-terminal targeting signal of GLUT4 glucose transporter in fibroblasts.

1994 • 110 citations

Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes.

1993 • 98 citations

Localization of transferrin receptors and insulin-like growth factor II receptors in vesicles from 3T3-L1 adipocytes that contain intracellular glucose transporters.

1989 • 96 citations

Isoform-specific subcellular targeting of glucose transporters in mouse fibroblasts.

1992 • 95 citations

Insulin-stimulated Translocation of the HepG2/Erythrocyte-type Glucose Transporter Expressed in 3T3-L1 Adipocytes

1989 • 94 citations

Complex regulation of simple sugar transport in insulin-responsive cells

1992 • 89 citations

Development of an intracellular pool of glucose transporters in 3T3-L1 cells.

1992 • 88 citations

Exofacial epitope-tagged glucose transporter chimeras reveal COOH-terminal sequences governing cellular localization.

1993 • 81 citations

The amino terminus of GLUT4 functions as an internalization motif but not an intracellular retention signal when substituted for the transferrin receptor cytoplasmic domain

1994 • 80 citations

Identification of the carboxy terminus as important for the isoform-specific subcellular targeting of glucose transporter proteins.

1993 • 75 citations

Role of p21ras in insulin-stimulated glucose transport in 3T3-L1 adipocytes.

1994 • 73 citations

Immunological analysis of GLUT4-enriched vesicles. Identification of novel proteins regulated by insulin and diabetes

1993 • 72 citations

Determination of the rates of appearance and loss of glucose transporters at the cell surface of rat adipose cells

1991 • 68 citations

Insulin regulation of hexose transport in mouse 3T3-L1 cells expressing the human HepG2 glucose transporter

1990 • 67 citations

Domains that confer intracellular sequestration of the Glut4 glucose transporter in Xenopus oocytes.

1993 • 63 citations

Trafficking of glucose transporters in 3T3-L1 cells. Inhibition of trafficking by phenylarsine oxide implicates a slow dissociation of transporters from trafficking proteins

1992 • 62 citations

Development of the hormone-sensitive glucose transport activity in differentiating 3T3-L1 murine fibroblasts. Role of the two transporter species and their subcellular localization

1990 • 61 citations

Two glucose transporter isoforms are sorted differentially and are expressed in distinct cellular compartments

1992 • 48 citations

Expression of an insulin-regulatable glucose carrier in muscle and fat endothelial cells

1989 • 46 citations