Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy
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References (52)
In silico prediction of protein-protein interactions in human macrophages
2014 • 11,120 citations
Significance analysis of microarrays applied to the ionizing radiation response
2001 • 10,393 citations
Phenotypic Analysis of Antigen-Specific T Lymphocytes
1996 • 3,611 citations
DNA double-strand breaks: signaling, repair and the cancer connection
2001 • 2,372 citations
Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
2000 • 1,477 citations
Error-Tolerant Identification of Peptides in Sequence Databases by Peptide Sequence Tags
1994 • 1,475 citations
Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated
2004 • 1,253 citations
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
2004 • 1,226 citations
Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
1999 • 1,131 citations
Local Radiation Therapy of B16 Melanoma Tumors Increases the Generation of Tumor Antigen-Specific Effector Cells That Traffic to the Tumor
2005 • 894 citations
A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E.
1992 • 694 citations
Use of a Monoclonal Antibody (W6/32) in Structural Studies of HLA-A,B,C Antigens
1979 • 682 citations
Sublethal Irradiation of Human Tumor Cells Modulates Phenotype Resulting in Enhanced Killing by Cytotoxic T Lymphocytes
2004 • 532 citations
Quantitating Protein Synthesis, Degradation, and Endogenous Antigen Processing
2003 • 508 citations
The ER-Luminal Domain of the HCMV Glycoprotein US6 Inhibits Peptide Translocation by TAP
1997 • 472 citations
Irradiation of Tumor Cells Up-Regulates Fas and Enhances CTL Lytic Activity and CTL Adoptive Immunotherapy
2003 • 452 citations
The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route
1990 • 445 citations
Making sense of mass destruction: quantitating MHC class I antigen presentation
2003 • 426 citations
External Beam Radiation of Tumors Alters Phenotype of Tumor Cells to Render Them Susceptible to Vaccine-Mediated T-Cell Killing
2004 • 425 citations
Isolation of High Avidity Melanoma-Reactive CTL from Heterogeneous Populations Using Peptide-MHC Tetramers
1999 • 423 citations
The major substrates for TAP in vivo are derived from newly synthesized proteins
2000 • 408 citations
An Essential Role of Sam50 in the Protein Sorting and Assembly Machinery of the Mitochondrial Outer Membrane
2003 • 326 citations
A Viral ER-Resident Glycoprotein Inactivates the MHC-Encoded Peptide Transporter
1997 • 314 citations
Workshop R: Tumor Immunology, Abstract R1 bis R30
2001 • 312 citations
Peptide Diffusion, Protection, and Degradation in Nuclear and Cytoplasmic Compartments before Antigen Presentation by MHC Class I
2003 • 298 citations
Recycling MHC class I molecules and endosomal peptide loading
1999 • 290 citations
A Major Role for TPPII in Trimming Proteasomal Degradation Products for MHC Class I Antigen Presentation
2004 • 263 citations
High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens
2005 • 233 citations
Allele and locus‐specific differences in cell surface expression and the association of HLA class I heavy chain with β2‐microglobulin: differential effects of inhibition of glycosylation on class I subunit association
1988 • 224 citations
ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair
1998 • 218 citations
H-2 class I knockout, HLA-A2.1-transgenic mice: a versatile animal model for preclinical evaluation of antitumor immunotherapeutic strategies
1999 • 182 citations
Late and persistent up-regulation of intercellular adhesion molecule-1 (ICAM-1) expression by ionizing radiation in human endothelial cells in vitro
1997 • 159 citations
Transduction and expression of the human carcinoembryonic antigen gene in a murine colon carcinoma cell line.
1991 • 149 citations
Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processing
2001 • 147 citations
The Abscopal Effect in Malignant Lymphoma and Its Relationship to Lymphocyte Circulation
1969 • 137 citations
Abrogation of CTL Epitope Processing by Single Amino Acid Substitution Flanking the C-Terminal Proteasome Cleavage Site
2000 • 95 citations
Irradiation induced expression of CD31, ICAM-1 and VCAM-1 in human microvascular endothelial cells.
2000 • 95 citations
Modulation of the Major Histocompatibility Complex Class II–Associated Peptide Repertoire by Human Histocompatibility Leukocyte Antigen (Hla)-Do
2000 • 89 citations
Peptide motifs of HLA-A1,-A11,-A31, and-A33 molecules
1994 • 88 citations
Induction of an Antigen Cascade by Diversified Subcutaneous/Intratumoral Vaccination Is Associated with Antitumor Responses
2005 • 81 citations
Folding and assembly of major histocompatibility complex class I heterodimers in the endoplasmic reticulum of intact cells precedes the binding of peptide.
1993 • 73 citations
Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1.
2004 • 65 citations
The Envelope Protein of an Endogenous Murine Retrovirus Is a Tumor-Associated T-Cell Antigen for Multiple Murine Tumors
2000 • 64 citations
Effects of irradiation on the expression of major histocompatibility complex class I antigen and adhesion costimulation molecules ICAM-1 in human cervical cancer
1997 • 62 citations
Localization of a gene controlling the expression of the human transferrin receptor to the region q12→qter of chromosome 3
1983 • 51 citations
Identification of Differentially Expressed Genes in Mouse Kidney after Irradiation using Microarray Analysis
2004 • 48 citations
Free radical initiation in proteins and amino acids by ionizing and ultraviolet radiations and lipid oxidation — part I: Ionizing radiation
1980 • 46 citations
Biological basis of radiation sensitivity. Part 2: Cellular and molecular determinants of radiosensitivity.
2000 • 41 citations
Ionizing radiation enhances immunogenicity of cells expressing a tumor-specific T-cell epitope
1999 • 30 citations
Isolation of an HLA‐A2.1 extracted human minor histocompatibility peptide
1993 • 21 citations
Biological Basis of Radiation Sensitivity
2000 • 13 citations
Effect of radiation on the expression of carcinoembryonic antigen on the membranes of human gastric adenocarcinoma cells--immunological study using monoclonal antibodies.
1988 • 8 citations
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