Ionizing radiation enhances immunogenicity of cells expressing a tumor-specific T-cell epitope

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1996 • 1,908 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

Systemic Exposure to Irradiated Apoptotic Cells Induces Autoantibody Production

1998 • 573 citations

Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group.

1990 • 515 citations

Decreased antigen presentation by dendritic cells in patients with breast cancer.

1997 • 439 citations

Karnofsky Memorial Lecture. The immunotherapy and gene therapy of cancer.

1992 • 394 citations

Frequent mutation of the p53 gene in human esophageal cancer.

1990 • 393 citations

Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy

1997 • 316 citations

The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutational hot spot.

1992 • 283 citations

Dendritic Cells in Antitumor Immune Responses

1996 • 282 citations

In vitro induction of human cytotoxic T lymphocyte responses against peptides of mutant and wild‐type p53

1993 • 267 citations

Human papillomavirus type 16 nucleoprotein E7 is a tumor rejection antigen.

1991 • 249 citations

Wild-type but not mutant p53 suppresses the growth of human lung cancer cells bearing multiple genetic lesions.

1992 • 200 citations

Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer

1991 • 173 citations

A mutant p53 tumor suppressor protein is a target for peptide-induced CD8+ cytotoxic T-cells.

1993 • 171 citations

A mouse mutant p53 product recognized by CD4+ and CD8+ T cells.

1994 • 168 citations

Mutations in the p53 gene in primary human breast cancers.

1991 • 165 citations

Induction of CD8⁺ cytotoxic T lymphocytes by immunization with syngeneic irradiated HIV-1 envelope derived peptide-pulsed dendritic cells

1993 • 138 citations

Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein.

1989 • 102 citations

CD4+ T cell clones specific for the human p97 melanoma-associated antigen can eradicate pulmonary metastases from a murine tumor expressing the p97 antigen.

1991 • 86 citations

Dominant determinants in hen eggwhite lysozyme correspond to the cryptic determinants within its self-homologue, mouse lysozyme: implications in shaping of the T cell repertoire and autoimmunity.

1993 • 84 citations

A Mutant Cell in Which Association of Class I Heavy and Light Chains Is Induced by Viral Peptides

1989 • 55 citations

Class II-restricted presentation of a hen egg lysozyme determinant derived from endogenous antigen sequestered in the cytoplasm or endoplasmic reticulum of the antigen presenting cells.

1993 • 45 citations

Human lung cancer cells endogenously expressing mutant p53 process and present the mutant epitope and are lysed by mutant-specific cytotoxic T lymphocytes

1996 • 24 citations

Mutant Oncopeptide Immunization Induces CTL Specifically Lysing Tumor Cells Endogenously Expressing the Corresponding Intact Mutant p53

1995 • 16 citations

THE TREATMENT OF MASTOCYTOMA CELLS WITH 8‐METHOXYPSORALEN AND LONG‐WAVELENGTH ULTRAVIOLET RADIATION ENHANCES CELLULAR IMMUNOGENICITY: PRELIMINARY RESULTS

1993 • 15 citations

Increased immunogenicity of tumors bearing mutant p53 and P1A epitopes after transduction of B7-1 via recombinant adenovirus.

1996 • 15 citations

Effect of ultraviolet irradiation on MCA102 tumor cell immunogenicity and sensitivity to tumor necrosis factor.

1991 • 12 citations

Threshold detection of self-antigen/MHC class II complexes formed in vivo: constitutive presentation of an immunodominant epitope of hen egg lysozyme (HEL) in HEL-transgenic mice

1993 • 11 citations