An intragenic methylated region in the imprinted Igf2 gene augments transcription

Genomic imprinting: parental influence on the genome

2001 • 2,253 citations

Methylation-Induced Repression— Belts, Braces, and Chromatin

1999 • 1,823 citations

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

2000 • 1,706 citations

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting

1990 • 1,650 citations

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

2000 • 1,493 citations

CpG islands as gene markers in the human genome

1992 • 908 citations

Transcription and Translation — A Practical Approach

1985 • 811 citations

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

2001 • 687 citations

The DNA methylation paradox

1999 • 642 citations

Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2

1998 • 641 citations

Imprinting and the Epigenetic Asymmetry Between Parental Genomes

2001 • 411 citations

An enhancer deletion affects both H19 and Igf2 expression.

1995 • 398 citations

Transcription and translation : a Practical Approach

1984 • 375 citations

The ontogeny of allele-specific methylation associated with imprinted genes in the mouse.

1993 • 345 citations

Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene.

1992 • 279 citations

Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes

1994 • 277 citations

Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2

1997 • 248 citations

Imprinting mutations in the Beckwith—Wiedemann syndrome suggested by an altered imprinting pattern in the IGF2–H19 domain

1995 • 215 citations

Chapter 27. Transcription of RNA in Isolated Nuclei

1978 • 211 citations

Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19

2000 • 203 citations

Mechanisms of genomic imprinting

1999 • 203 citations

DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa

1997 • 202 citations

Three transitions in the RNA polymerase II transcription complex during initiation

1997 • 181 citations

DNA Methylation Differences Associated with Tumor Tissues Identified by Genome Scanning Analysis

1998 • 112 citations

Loss of the maternal H19 gene induces changes in Igf 2 methylation in both cis and trans

1997 • 105 citations

An upstream repressor element plays a role in Igf2 imprinting

2001 • 99 citations

Sequence of a Placental cDNA Encoding the Mouse Insulin-Like Growth Factor II Precursor

1986 • 93 citations

Allelic methylation of H19 and IGF2 in the Beckwith — Wiedemann syndrome

1994 • 87 citations

The uniqueness of the imprinting mechanism

2000 • 83 citations

Extensive tissue-specific variation of allelic methylation in the Igf2 gene during mouse fetal development: relation to expression and imprinting

2001 • 58 citations

A skeletal muscle-specific mouse Igf2 repressor lies 40 kb downstream of the gene

2000 • 54 citations

Mouse genetics and transgenics : a practical approach

2000 • 53 citations

Mouse genetics and transgenics: a practical approach

2000 • 52 citations

Overexpression of DNA Methyltransferase in Myoblast Cells Accelerates Myotube Formation

1995 • 49 citations

Rapid Construction in Yeast of Complex Targeting Vectors for Gene Manipulation in the Mouse

1996 • 48 citations

Growth-condition-dependent regulation of insulin-like growth factor II mRNA stability

1996 • 17 citations

Deleted Work

1955 • 0 citations