Mitotic phosphorylation of SUV39H1, a novel component of active centromeres, coincides with transient accumulation at mammalian centromeres

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1984 • 3,959 citations

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

1997 • 1,814 citations

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

1999 • 929 citations

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

1995 • 822 citations

Identification of a Human Mitotic Checkpoint Gene: hsMAD2

1996 • 609 citations

Identification of Xenopus SMC protein complexes required for sister chromatid cohesion

1998 • 594 citations

The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes.

1994 • 560 citations

Kinetochore Localization of Murine Bub1 Is Required for Normal Mitotic Timing and Checkpoint Response to Spindle Damage

1997 • 543 citations

The case for epigenetic effects on centromere identity and function

1997 • 470 citations

Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation.

1995 • 447 citations

Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31

1999 • 433 citations

CENP-E Is a Plus End–Directed Kinetochore Motor Required for Metaphase Chromosome Alignment

1997 • 428 citations

CENP-E is a putative kinetochore motor that accumulates just before mitosis

1992 • 424 citations

The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast

1999 • 404 citations

SET domain proteins modulate chromatin domains in eu- and heterochromatin

1998 • 374 citations

Transient Inhibition of Histone Deacetylation Alters the Structural and Functional Imprint at Fission Yeast Centromeres

1997 • 367 citations

Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres

1997 • 336 citations

Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells

1999 • 327 citations

A functional neo-centromere formed through activation of a latent human centromere and consisting of non-alpha-satellite DNA

1997 • 319 citations

The heterochromatin-associated protein HP-1 is an essential protein in Drosophila with dosage-dependent effects on position-effect variegation.

1992 • 318 citations

Position effect variegation and chromatin proteins

1992 • 311 citations

Assembly of CENP-A into Centromeric Chromatin Requires a Cooperative Array of Nucleosomal DNA Contact Sites

1997 • 295 citations

Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation

1998 • 295 citations

One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis

1990 • 291 citations

PhosphoBase, a database of phosphorylation sites: release 2.0

1999 • 287 citations

Yeast Heterochromatin: Regulation of Its Assembly and Inheritance by Histones

1998 • 286 citations

Something from nothing: the evolution and utility of satellite repeats

1998 • 283 citations

The Heterochromatin Protein 1 Prevents Telomere Fusions in Drosophila

1998 • 274 citations

Functional analysis of the chromo domain of HP1.

1995 • 259 citations

Mutations in the fission yeast silencing factors clr4 + and rik1 + disrupt the localisation of the chromo domain protein Swi6p and impair centromere function

1996 • 241 citations

Association of SET domain and myotubularin-related proteins modulates growth control

1998 • 240 citations

Centromere Protein B Null Mice are Mitotically and Meiotically Normal but Have Lower Body and Testis Weights

1998 • 237 citations

Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster.

1992 • 231 citations

Identification of centromeric antigens in dicentric Robertsonian translocations: CENP-C and CENP-E are necessary components of functional centromeres

1995 • 223 citations

Unfolding the mysteries of heterochromatin

1998 • 222 citations

INCENP Centromere and Spindle Targeting: Identification of Essential Conserved Motifs and Involvement of Heterochromatin Protein HP1

1998 • 208 citations

A mammalian homologue of Drosophila heterochromatin protein 1 (HP1) is a component of constitutive heterochromatin

1994 • 196 citations

Neocentromere activity of structurally acentric mini-chromosomes in Drosophila

1998 • 193 citations

Analysis of the distribution of the INCENPs throughout mitosis reveals the existence of a pathway of structural changes in the chromosomes during metaphase and early events in cleavage furrow formation

1991 • 176 citations

Structure of the chromatin binding (chromo) domain from mouse modifier protein 1

1997 • 170 citations

The chromo and SET domains of the Clr4 protein are essential for silencing in fission yeast

1998 • 166 citations

Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity

1993 • 162 citations

Fission Yeast Bub1 Is a Mitotic Centromere Protein Essential for the Spindle Checkpoint and the Preservation of Correct Ploidy through Mitosis

1998 • 156 citations

Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p

1999 • 149 citations

Targeted disruption of mouse centromere protein C gene leads to mitotic disarray and early embryo death

1998 • 143 citations

Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes.

1991 • 107 citations

M32, a murine homologue of Drosophila heterochromatin protein 1 (HP1), localises to euchromatin within interphase nuclei and is largely excluded from constitutive heterochromatin

1996 • 91 citations

p34^cdc2 Kinase is localized to distinct domains within the mitotic apparatus

1990 • 91 citations

Centromere proteins and chromosome inheritance: a complex affair

1999 • 89 citations

Mutations in the protein phosphatase 1 gene at 87B can differentially affect suppression of position-effect variegation and mitosis in Drosophila melanogaster.

1993 • 75 citations

Phosphorylation of Heterochromatin Protein 1 by Casein Kinase II Is Required for Efficient Heterochromatin Binding inDrosophila

1999 • 73 citations

Heterochromatin protein HP1 Hsβ (p25β) and its localization with centromeres in mitosis

1997 • 65 citations

Phosphoamino Acid Analysis

1996 • 7 citations

Centromere proteins of higher eukaryotes

1997 • 1 citations