Centromere Protein B Null Mice are Mitotically and Meiotically Normal but Have Lower Body and Testis Weights

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

1993 • 2,370 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1994 • 1,472 citations

Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma

1985 • 803 citations

Daily sperm production and epididymal sperm reserves of pubertal and adult rats

1978 • 762 citations

A stem-loop in the 3′ untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm

1988 • 565 citations

The case for epigenetic effects on centromere identity and function

1997 • 470 citations

Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere.

1994 • 444 citations

CENP-E is a putative kinetochore motor that accumulates just before mitosis

1992 • 424 citations

Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen

1987 • 420 citations

Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C.

1995 • 410 citations

A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones

1987 • 401 citations

A mutation in CSE4, an essential gene encoding a novel chromatin-associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis.

1995 • 393 citations

Direct Evidence of a Role for Heterochromatin in Meiotic Chromosome Segregation

1996 • 386 citations

CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase.

1991 • 384 citations

The CREST syndrome: A distinct serologic entity with anticentromere antibodies

1980 • 369 citations

The Centromere: Hub of Chromosomal Activities

1995 • 353 citations

CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate

1992 • 340 citations

A functional neo-centromere formed through activation of a latent human centromere and consisting of non-alpha-satellite DNA

1997 • 319 citations

Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.

1994 • 319 citations

Kinetochore structure, duplication, and distribution in mammalian cells: analysis by human autoantibodies from scleroderma patients.

1981 • 312 citations

Visualization of centromere proteins CENP-B and CENP-C on a stable dicentric chromosome in cytological spreads

1989 • 293 citations

A functional marker centromere with no detectable alpha-satellite, satellite III, or CENP-B protein: activation of a latent centromere?

1993 • 261 citations

A survey of the genomic distribution of alpha satellite DNA on all the human chromosomes, and derivation of a new consensus sequence

1991 • 242 citations

CENP-B: a major human centromere protein located beneath the kinetochore.

1990 • 238 citations

Identification of centromeric antigens in dicentric Robertsonian translocations: CENP-C and CENP-E are necessary components of functional centromeres

1995 • 223 citations

Centromere protein B assembles human centromeric alpha-satellite DNA at the 17-bp sequence, CENP-B box.

1992 • 210 citations

Centric Heterochromatin and the Efficiency of Achiasmate Disjunction in Drosophila Female Meiosis

1996 • 206 citations

CENP-C is required for maintaining proper kinetochore size and for a timely transition to anaphase.

1994 • 200 citations

Centromere DNA Dynamics: Latent Centromeres and Neocentromere Formation

1997 • 197 citations

Centromeres, CENP-B and Tigger too

1997 • 196 citations

Theory and practice of stereological techniques applied to the estimation of cell number and nuclear volume in the testis

1995 • 188 citations

Characterization of neo-centromeres in marker chromosomes lacking detectable alpha-satellite DNA

1997 • 179 citations

Structure of the major block of alphoid satellite DNA on the human Y chromosome

1987 • 163 citations

Distribution of CENP-B boxes reflected in CREST centromere antigenic sites on long-range α-satellite DNA arrays of human chromosome 21

1994 • 154 citations

Distribution of kinetochore (centromere) antigen in mammalian cell nuclei.

1981 • 147 citations

Injection of anticentromere antibodies in interphase disrupts events required for chromosome movement at mitosis.

1990 • 147 citations

Targeted disruption of mouse centromere protein C gene leads to mitotic disarray and early embryo death

1998 • 143 citations

A human centromere protein, CENP-B, has a DNA binding domain containing four potential alpha helices at the NH2 terminus, which is separable from dimerizing activity.

1992 • 132 citations

Antibodies to defined histone epitopes reveal variations in chromatin conformation and underacetylation of centric heterochromatin in human metaphase chromosomes

1992 • 128 citations

Identification of a subdomain of CENP-B that is necessary and sufficient for localization to the human centromere.

1992 • 120 citations

CENP-B is a highly conserved mammalian centromere protein with homology to the helix-loop-helix family of proteins

1991 • 117 citations

Construction of a smallMus musculusrepetitive DNA library: identification of a new satedllite sequence inMus musculus

1983 • 113 citations

Microinjected centromere [corrected] kinetochore antibodies interfere with chromosome movement in meiotic and mitotic mouse oocytes [published erratum appears in J Cell Biol 1990 Dec;111(6 Pt 1):following 2800]

1990 • 109 citations

MIF2 is required for mitotic spindle integrity during anaphase spindle elongation in Saccharomyces cerevisiae.

1993 • 106 citations

CENP-B Binds a Novel Centromeric Sequence in the Asian Mouse Mus caroli

1995 • 106 citations

Efficient conditional mutation of the vertebrate CENP-C gene

1997 • 104 citations

Alphoid satellite DNA is tightly associated with centromere antigens in human chromosomes throughout the cell cycle

1989 • 104 citations

Presence and abundance of CENP-B box sequences in great ape subsets of primate-specific ?-satellite DNA

1995 • 101 citations

Disruption of centromere assembly during interphase inhibits kinetochore morphogenesis and function in mitosis

1991 • 96 citations

Long-range analyses of the centromeric regions of human chromosomes 13, 14 and 21: identification of a narrow domain containing two key centromeric DNA elements

1993 • 86 citations

Further evidence that CENP-C is a necessary component of active centromeres: studies of a dic(X; 15) with simultaneous immunofluorescence and FISH

1995 • 81 citations

Evidence for Selection in Evolution of Alpha Satellite DNA: The Central Role of CENP-B/pJα Binding Region

1996 • 80 citations

Quantitative RT-PCR assays show Xist RNA levels are low in mouse female adult tissue, embryos and embryoid bodies

1994 • 79 citations

Role of nonhistone proteins in the chromosomal events of mitosis

1994 • 77 citations

Sequence similarities between the yeast chromosome segregation protein Mif2 and the mammalian centromere protein CENP-C

1995 • 75 citations

The structure of the mammalian centromere

1991 • 75 citations

Definition of a new alpha satellite suprachromosomal family characterized by monomeric organization

1993 • 74 citations

Surprising Deficiency of CENP-B Binding Sites in African Green Monkey α-Satellite DNA: Implications for CENP-B Function at Centromeres

1996 • 73 citations

Mouse centromere mapping using oligonucleotide probes that detect variants of the minor satellite

1994 • 68 citations

Structure and molecular organization of the centromere-kinetochore complex

1992 • 67 citations

Analysis of Protein-DNA and Protein-Protein Interactions of Centromere Protein B (CENP-B) and Properties of the DNA-CENP-B Complex in the Cell Cycle

1995 • 64 citations

A stable acentric marker chromosome: possible existence of an intercalary ancient centromere at distal 8p.

1994 • 61 citations

Kinetochore components recognized by human autoantibodies are present on mononucleosomes.

1985 • 61 citations

A Centromere DNA-binding Protein from Fission Yeast Affects Chromosome Segregation and Has Homology to Human CENP-B

1997 • 55 citations

Centromere Protein B of African Green Monkey Cells: Gene Structure, Cellular Expression, and Centromeric Localization

1996 • 55 citations

Purification and characterization of a CENP-B homologue protein that binds to the centromeric K-type repeat DNA of Schizosaccharomyces pombe

1997 • 44 citations

Higher rate of evolution of X chromosome alpha-repeat DNA in human than in the great apes.

1992 • 35 citations

A novel nuclear protein binds centromeric alpha satellite DNA

1994 • 34 citations

Characterization and chromosomal location of two repeated DNAs in three Gerbillus species

1995 • 32 citations

Rabl orientation of CENP-B box sequences in Tupaia belangeri fibroblasts

1995 • 24 citations

Kinetochore Components Recognized by Human Autoantibodies Are Present on Mononucleosomes

1985 • 23 citations

Satellite 1 DNA sequence from genomic DNA of the giant pandaAiluropoda melanoleuca

1990 • 22 citations

Molecular cloning of an intronless gene for the hamster centromere antigen CENP-B

1996 • 19 citations

Evolutionary relationships of multiple alpha satellite subfamilies in the centromeres of human chromosomes 13, 14, and 21

1992 • 15 citations

Mapping of the Human Centromere Protein B Gene (CENPB) to Chromosome 20p13 by Fluorescence in Situ Hybridization

1994 • 2 citations

Mapping of the Human CENP-B Gene to Chromosome 20 and the CENP-C Gene to Chromosome 12 by a Rapid Cycle DNA Amplification Procedure

1993 • 2 citations