Structure of the chromatin binding (chromo) domain from mouse modifier protein 1

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

NMR of Proteins and Nucleic Acids

2006 • 5,989 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

Improved spectral resolution in COSY 1H NMR spectra of proteins via double quantum filtering

1983 • 2,327 citations

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

1980 • 1,886 citations

Rapid recording of 2D NMR spectra without phase cycling. Application to the study of hydrogen exchange in proteins

1989 • 1,395 citations

Calculating the electrostatic potential of molecules in solution: Method and error assessment

1988 • 1,096 citations

Correlating backbone amide and side chain resonances in larger proteins by multiple relayed triple resonance NMR

1992 • 1,012 citations

Calibration of the angular dependence of the amide proton-Cα proton coupling constants, 3JHNα, in a globular protein

1984 • 956 citations

[12] Chemical shifts as a tool for structure determination

1994 • 865 citations

Overcoming the overlap problem in the assignment of proton NMR spectra of larger proteins by use of three-dimensional heteronuclear proton-nitrogen-15 Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: application to interleukin 1.beta.

1989 • 840 citations

A novel approach for sequential assignment of proton, carbon-13, and nitrogen-15 spectra of larger proteins: heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin

1990 • 836 citations

Calculation of the total electrostatic energy of a macromolecular system: Solvation energies, binding energies, and conformational analysis

1988 • 829 citations

Human monocyte chemoattractant protein-1 (MCP-1)

1990 • 666 citations

MAMMALIAN X-CHROMOSOME INACTIVATION

1983 • 635 citations

1H1H correlation via isotropic mixing of 13C magnetization, a new three-dimensional approach for assigning 1H and 13C spectra of 13C-enriched proteins

1990 • 580 citations

The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila.

1991 • 566 citations

Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.

1990 • 554 citations

Determination of three‐dimensional structures of proteins from interproton distance data by dynamical simulated annealing from a random array of atoms Circumventing problems associated with folding

1988 • 546 citations

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

1996 • 532 citations

Comparison of different modes of two-dimensional reverse-correlation NMR for the study of proteins

1990 • 510 citations

DIFFERENTIAL IMPRINTING AND EXPRESSION OF MATERNAL AND PATERNAL GENOMES

1988 • 451 citations

Two-dimensional NMR experiments for correlating carbon-13.beta. and proton.delta./.epsilon. chemical shifts of aromatic residues in 13C-labeled proteins via scalar couplings

1993 • 440 citations

Interaction between an Integral Protein of the Nuclear Envelope Inner Membrane and Human Chromodomain Proteins Homologous to HP1

1996 • 398 citations

An efficient experiment for sequential backbone assignment of medium-sized isotopically enriched proteins

1992 • 391 citations

Imprinting a determined state into the chromatin of Drosophila

1990 • 391 citations

Direct Evidence of a Role for Heterochromatin in Meiotic Chromosome Segregation

1996 • 386 citations

Calculation of Protein Structures with Ambiguous Distance Restraints. Automated Assignment of Ambiguous NOE Crosspeaks and Disulphide Connectivities

1995 • 352 citations

The heterochromatin-associated protein HP-1 is an essential protein in Drosophila with dosage-dependent effects on position-effect variegation.

1992 • 318 citations

Position effect variegation and chromatin proteins

1992 • 311 citations

Four-Dimensional Heteronuclear Triple-Resonance NMR Spectroscopy of Interleukin-1β in Solution

1990 • 308 citations

The Chromodomain Protein Swi6: A Key Component at Fission Yeast Centromeres

1995 • 300 citations

Silencers, silencing, and heritable transcriptional states

1992 • 296 citations

A sequence motif found in aDrosophilaheterochromatin protein is conserved in animals and plants

1991 • 273 citations

An alternative 3D NMR technique for correlating backbone 15N with side chain Hβ resonances in larger proteins

1991 • 273 citations

Solution Structure and Dynamics of Ras p21.cntdot.GDP Determined by Heteronuclear Three- and Four-Dimensional NMR Spectroscopy

1994 • 271 citations

Functional analysis of the chromo domain of HP1.

1995 • 259 citations

Comparison of techniques for 1H-detected heteronuclear 1H15N Spectroscopy

1990 • 251 citations

The chromo shadow domain, a second chromo domain in heterochromatin-binding protein 1, HP1

1995 • 236 citations

Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster.

1992 • 231 citations

A mammalian DNA-binding protein that contains a chromodomain and an SNF2/SWI2-like helicase domain.

1993 • 230 citations

Centric Heterochromatin and the Efficiency of Achiasmate Disjunction in Drosophila Female Meiosis

1996 • 206 citations

Pdd1p, A Novel Chromodomain-Containing Protein, Links Heterochromatin Assembly and DNA Elimination in Tetrahymena

1996 • 183 citations

The chromo superfamily: new members, duplication of the chromo domain and possible role in delivering transcription regulators to chromatin

1995 • 182 citations

Solution structure and DNA-binding properties of a thermostable protein from the archaeon Sulfolobus solfataricus

1994 • 163 citations

Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals

1994 • 163 citations

Measurement of three-bond nitrogen-carbon J couplings in proteins uniformly enriched in nitrogen-15 and carbon-13

1993 • 144 citations

The high-resolution, three-dimensional solution structure of human interleukin-4 determined by multidimensional heteronuclear magnetic resonance spectroscopy

1993 • 124 citations

Mechanisms of heritable gene repression during development of Drosophila

1993 • 113 citations

A simple and sensitive experiment for measurement of JCC couplings between backbone carbonyl and methyl carbons in isotopically enriched proteins

1993 • 106 citations

Three-dimensional 13C-resolved proton NOE spectroscopy of uniformly 13C-labeled proteins for the NMR assignment and structure determination of larger molecules

1990 • 97 citations

Precise vicinal coupling constants3JHNα in proteins from nonlinear fits of J-modulated [15N,1H]-COSY experiments

1992 • 97 citations

Overlapping domains of the heterochromatin-associated protein HP1 mediate nuclear localization and heterochromatin binding.

1993 • 95 citations

Silencers, silencing, and heritable transcriptional states.

1992 • 78 citations

Solution Structure of the DNA-Binding Protein Sac7d from the Hyperthermophile Sulfolobus acidocaldarius

1995 • 64 citations

Cloning and expression of Drosophila HP1 homologs from a mealybug, Pianococcus citri

1992 • 62 citations

A 4D HCC(CO)NNH experiment for the correlation of aliphatic side-chain and backbone resonances in 13C/15N-labelled proteins

1993 • 62 citations

Transcription: new insights from studies on Archaea

1995 • 55 citations

DNA-binding Surface of the Sso7d Protein fromSulfolobus solfataricus

1995 • 45 citations

Subcellular localization of the retinoblastoma protein.

1991 • 39 citations

Heterochromatin protein 1, a known suppressor of position-effect variegation, is highly conserved inDrosophila

1992 • 36 citations

Improved methods for structural studies of proteins using nuclear magnetic resonance spectroscopy

1995 • 7 citations