The Function of Multisite Splicing Enhancers

The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences

1992 • 1,338 citations

Transcriptional activation by recruitment

1997 • 1,163 citations

Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome

1995 • 994 citations

Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

1993 • 741 citations

THE STRUCTURE AND FUNCTION OF PROTEINS INVOLVED IN MAMMALIAN PRE-mRNA SPLICING

1996 • 687 citations

Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides

1989 • 685 citations

The superfamily of arginine/serine-rich splicing factors.

1995 • 671 citations

SR proteins and splicing control.

1996 • 668 citations

Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

1994 • 622 citations

A role for exon sequences and splice-site proximity in splice-site selection

1986 • 494 citations

Sex in flies: the splice of life

1989 • 468 citations

Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene

1987 • 406 citations

A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives

1990 • 386 citations

The role of exon sequences in splice site selection.

1993 • 367 citations

Control of doublesex Alternative Splicing by transformer and transformer-2 in Drosophila

1991 • 333 citations

A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA

1993 • 332 citations

Eukaryotic activators function during multiple steps of preinitiation complex assembly

1993 • 311 citations

The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing.

1996 • 286 citations

Initial splice-site recognition and pairing during pre-mRNA splicing

1996 • 281 citations

How different eukaryotic transcriptional activators can cooperate promiscuously

1990 • 261 citations

Mechanisms of Alternative Pre-mRNA Splicing

1991 • 257 citations

Cooperative binding of drosophila heat shock factor to arrays of a conserved 5 bp unit

1991 • 250 citations

Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer.

1996 • 228 citations

Cooperative DNA binding of the yeast transcriptional activator GAL4.

1988 • 227 citations

Positive Control of Pre-mRNA Splicing in Vitro

1992 • 199 citations

Directing alternative splicing: cast and scenarios

1996 • 187 citations

A general mechanism for transcriptional synergy by eukaryotic activators

1995 • 185 citations

The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2

1994 • 182 citations

Ectopic expression of the female transformer gene product leads to female differentiation of chromosomally male drosophila

1988 • 157 citations

Synergistic interactions between two distinct elements of a regulated splicing enhancer.

1995 • 156 citations

Common themes in the function of transcription and splicing enhancers

1997 • 151 citations

A splicing enhancer exhibits both constitutive and regulated activities.

1994 • 136 citations

Free energy coupling within macromolecules

1983 • 123 citations

A molecular analysis of transformer, a gene in drosophila melanogaster that controls female sexual differentiation

1987 • 119 citations

Regulation of pre-mRNA splicing in metazoa

1997 • 110 citations

Mechanisms of transcription complex assembly

1996 • 89 citations

Two Different Sequence Elements within Exon 4 Are Necessary for Calcitonin-Specific Splicing of the Human Calcitonin/Calcitonin Gene-Related Peptide I Pre-mRNA

1994 • 47 citations

Cooperative binding of R17 coat protein to RNA

1990 • 46 citations

Modulating the Potency of an Activator in a Yeast In Vitro Transcription System

1994 • 42 citations

Structural and functional conservation of the Drosophila doublesex splicing enhancer repeat elements.

1996 • 34 citations

Modulating the potency of an activator in a yeast in vitro transcription system.

1994 • 27 citations

Spliceosome assembly

1997 • 18 citations

Two different sequence elements within exon 4 are necessary for calcitonin-specific splicing of the human calcitonin/calcitonin gene-related peptide I pre-mRNA.

1994 • 16 citations

The Migrations of “Salmo Salar” (L.) in the Baltic

1884 • 4 citations