Apolipoprotein A-I: structure–function relationships

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

de la Chapelle, A.

1997 • 3,184 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

1999 • 1,708 citations

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

1999 • 1,527 citations

Molecular physiology of reverse cholesterol transport.

1995 • 1,452 citations

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

1999 • 1,441 citations

A thermodynamic approach to the problem of stabilization of globular protein structure: A calorimetric study

1974 • 1,384 citations

Plasma lipoproteins: apolipoprotein structure and function.

1984 • 1,130 citations

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

1999 • 732 citations

A molecular theory of lipid—protein interactions in the plasma lipoproteins

1974 • 725 citations

A protein cofactor of lecithin:Cholesterol acyltransferase

1972 • 722 citations

Scavenger Receptor BI Promotes High Density Lipoprotein-mediated Cellular Cholesterol Efflux

1997 • 694 citations

Three-Dimensional Structure of the LDL Receptor-Binding Domain of Human Apolipoprotein E

1991 • 661 citations

Early incorporation of cell-derived cholesterol into pre-.beta.-migrating high-density lipoprotein

1988 • 643 citations

Lecithin cholesterol acyltransferase

2000 • 460 citations

Micellar complexes of human apolipoprotein A-I with phosphatidylcholines and cholesterol prepared from cholate-lipid dispersions.

1982 • 438 citations

Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation

1997 • 417 citations

The amino acid sequence of human Apoa-I, an apolipoprotein isolated from high density lipoproteins

1978 • 360 citations

Mutations in the ABC 1 gene in familial HDL deficiency with defective cholesterol efflux

1999 • 358 citations

Apolipoprotein-mediated removal of cellular cholesterol and phospholipids

1996 • 346 citations

Activation of lecithin: cholesterol acyltransferase by human apolipoprotein A-IV.

1985 • 339 citations

A Detailed Molecular Belt Model for Apolipoprotein A-I in Discoidal High Density Lipoprotein

1999 • 334 citations

The apolipoprotein multigene family: biosynthesis, structure, structure-function relationships, and evolution.

1988 • 315 citations

Studies of synthetic peptide analogs of the amphipathic helix. Structure of complexes with dimyristoyl phosphatidylcholine.

1985 • 314 citations

The Amphipathic α Helix: A Multifunctional Structural Motif in Plasma Apolipoproteins

1994 • 307 citations

Intracellular cholesterol transport

1997 • 295 citations

Scavenger Receptor Class B Type I as a Mediator of Cellular Cholesterol Efflux to Lipoproteins and Phospholipid Acceptors

1998 • 291 citations

Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux.

1992 • 269 citations

The intrinsic factor–vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein

1999 • 268 citations

Human ATP-binding cassette transporter 1 (ABC1): Genomic organization and identification of the genetic defect in the original Tangier disease kindred

1999 • 267 citations

Membrane Cholesterol Dynamics: Cholesterol Domains and Kinetic Pools

1991 • 262 citations

Isolation and characterization of the human apolipoprotein A-I gene.

1983 • 243 citations

Effects of Recombinant Apolipoprotein A-I _Milano on Aortic Atherosclerosis in Apolipoprotein E–Deficient Mice

1998 • 235 citations

Molecular structure of an apolipoprotein determined at 2.5-.ANG. resolution

1991 • 234 citations

Variant apolipoprotein AI as a major constituent of a human hereditary amyloid

1988 • 229 citations

Defined Apolipoprotein A-I Conformations in Reconstituted High Density Lipoprotein Discs

1989 • 222 citations

A-Imilano apoprotein. Isolation and characterization of a cysteine-containing variant of the A-I apoprotein from human high density lipoproteins.

1980 • 217 citations

Lecithin-cholesterol acyltransferase in the metabolism of high-density lipoproteins

1991 • 214 citations

Kinetics of lipid-protein interactions: interaction of apolipoprotein A-I from human plasma high density lipoproteins with phosphatidylcholines

1978 • 212 citations

The mechanism of activation of lecithin:cholesterol acyltransferase by apolipoprotein A-I and an amphiphilic peptide.

1980 • 204 citations

High density lipoprotein receptors, binding proteins, and ligands

1999 • 203 citations

Cellular cholesterol efflux

2001 • 193 citations

Only the Two End Helixes of Eight Tandem Amphipathic Helical Domains of Human Apo A-I Have Significant Lipid Affinity

1996 • 192 citations

Structure and thermodynamic properties of high density lipoprotein recombinants.

1977 • 192 citations

Apolipoprotein A-I Conformation in Reconstituted Discoidal Lipoproteins Varying in Phospholipid and Cholesterol Content

1995 • 189 citations

Efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides

1995 • 188 citations

Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol.

1994 • 187 citations

The bidirectional flux of cholesterol between cells and lipoproteins. Effects of phospholipid depletion of high density lipoprotein.

1986 • 186 citations

Apolipoprotein-mediated Plasma Membrane Microsolubilization

1999 • 180 citations

Apolipoprotein A-I structure and lipid properties in homogeneous, reconstituted spherical and discoidal high density lipoproteins.

1990 • 177 citations

Thermal unfolding of human high-density apolipoprotein A-1: implications for a lipid-free molten globular state.

1996 • 165 citations

Apolipoprotein A-IMilano. Detection of normal A-I in affected subjects and evidence for a cysteine for arginine substitution in the variant A-I.

1983 • 161 citations

Conformational analysis of apolipoprotein A-I and E-3 based on primary sequence and circular dichroism

1992 • 160 citations

Determining globular protein stability: guanidine hydrochloride denaturation of myoglobin

1979 • 157 citations

Isolation and characterization of cDNA clones for human apolipoprotein A-I.

1982 • 155 citations

The charge and structural stability of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles.

1992 • 153 citations

Synthetic high density lipoprotein particles. Application to studies of the apoprotein specificity for selective uptake of cholesterol esters.

1987 • 152 citations

PHYLOGENIES CONSTRAINED BY THE CROSSOVER PROCESS AS ILLUSTRATED BY HUMAN HEMOGLOBINS AND A THIRTEEN-CYCLE, ELEVEN-AMINO-ACID REPEAT IN HUMAN APOLIPOPROTEIN A-I

1977 • 152 citations

Studies on human serum high density lipoproteins. Self-association of apolipoprotein A-I in aqueous solutions.

1976 • 151 citations

Activation of lecithin : cholesterol acyltransferase by apolipoproteins E-2, E-3, and A-IV isolated from human plasma

1985 • 151 citations

Structural models of human apolipoprotein A-I

1995 • 145 citations

Apolipoprotein AI mutation Arg-60 causes autosomal dominant amyloidosis.

1992 • 143 citations

Predicting the structure of apolipoprotein A-I in reconstituted high-density lipoprotein disks

1997 • 138 citations

Gene structure of human apolipoprotein Al

1983 • 133 citations

The conformation of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles. 13C NMR studies of lysine ionization behavior.

1992 • 131 citations

The Structure of Human Lipoprotein A-I

1999 • 130 citations

Electron microscopic study on reassembly of plasma high density apoprotein with various lipids

1971 • 129 citations

Apolipoprotein A-I domains involved in lecithin-cholesterol acyltransferase activation. Structure:function relationships.

1993 • 123 citations

Binding of high density lipoprotein to cultured fibroblasts after chemical alteration of apoprotein amino acid residues.

1986 • 122 citations

Recruitment of cell phospholipids and cholesterol by apolipoproteins A-II and A-I: formation of nascent apolipoprotein-specific HDL that differ in size, phospholipid composition, and reactivity with LCAT

1995 • 120 citations

Repeated helical pattern in apolipoprotein-A-I

1977 • 120 citations

A frameshift mutation in the human apolipoprotein A-I gene causes high density lipoprotein deficiency, partial lecithin: cholesterol-acyltransferase deficiency, and corneal opacities.

1991 • 120 citations

Apolipoprotein A-I deficiency due to a codon 84 nonsense mutation of the apolipoprotein A-I gene.

1991 • 120 citations

Structural studies of apolipoprotein A-I/phosphatidylcholine recombinants by high-field proton NMR, nondenaturing gradient gel electrophoresis, and electron microscopy

1984 • 117 citations

In vivo metabolism of a mutant form of apolipoprotein A-I, apo A-IMilano, associated with familial hypoalphalipoproteinemia.

1993 • 115 citations

Sphingomyelin Inhibits the Lecithin-Cholesterol Acyltransferase Reaction with Reconstituted High Density Lipoproteins by Decreasing Enzyme Binding

1996 • 112 citations

Site-directed mutagenesis and structure-function analysis of the human apolipoprotein A-I. Relation between lecithin-cholesterol acyltransferase activation and lipid binding.

1992 • 112 citations

Hereditary Amyloid Cardiomyopathy Caused by a Variant Apolipoprotein A1

1999 • 112 citations

The molecular basis for the difference in charge between pre-beta- and alpha-migrating high density lipoproteins.

1994 • 112 citations

Cholesterol efflux mediated by apolipoproteins is an active cellular process distinct from efflux mediated by passive diffusion

1997 • 111 citations

Effects of the Neutral Lipid Content of High Density Lipoprotein on Apolipoprotein A-I Structure and Particle Stability

1995 • 110 citations

Properties of an N-terminal Proteolytic Fragment of Apolipoprotein AI in Solution and in Reconstituted High Density Lipoproteins

1995 • 110 citations

Apolipoprotein-mediated cellular cholesterol efflux

1998 • 108 citations

Truncation of the Amino Terminus of Human Apolipoprotein A-I Substantially Alters Only the Lipid-Free Conformation

1997 • 108 citations

Hereditary hepatic and systemic amyloidosis caused by a new deletion/insertion mutation in the apolipoprotein AI gene.

1996 • 108 citations

Reverse cholesterol transport

1986 • 107 citations

Mode of assembly of amphipathic helical segments in model high-density lipoproteins

1990 • 106 citations

Structural analysis of human apolipoprotein A-I variants. Amino acid substitutions are nonrandomly distributed throughout the apolipoprotein A-I primary structure.

1990 • 105 citations

Abnormal lecithin:cholesterol acyltransferase activation by a human apolipoprotein A-I variant in which a single lysine residue is deleted.

1984 • 103 citations

Studies of synthetic peptide analogs of the amphipathic helix. Correlation of structure with function.

1985 • 102 citations

On computer-assisted analysis of biological sequences: proline punctuation, consensus sequences, and apolipoprotein repeats.

1990 • 100 citations

Conformational and thermodynamic properties of apo A-1 of human plasma high density lipoproteins.

1976 • 99 citations

Role of HDL phospholipid in efflux of cell cholesterol to whole serum: studies with human apoA-I transgenic rats.

1996 • 98 citations

Regulation of lecithin cholesterol acyltransferase activity

1998 • 96 citations

The Carboxyl-terminal Hydrophobic Residues of Apolipoprotein A-I Affect Its Rate of Phospholipid Binding and Its Association with High Density Lipoprotein

1997 • 95 citations

Apolipoprotein A-I variants. Naturally occurring substitutions of proline residues affect plasma concentration of apolipoprotein A-I.

1989 • 95 citations

A Novel Apolipoprotein A-1 Variant, Arg173Pro, Associated with Cardiac and Cutaneous Amyloidosis

1999 • 94 citations

Cellular cholesterol efflux. Role of cell membrane kinetic pools and interaction with apolipoproteins AI, AII, and Cs.

1992 • 92 citations

Use of synthetic peptide analogues to localize lecithin:cholesterol acyltransferase activating domain in apolipoprotein A-I.

1990 • 92 citations

Characterization of discoidal complexes of phosphatidylcholine, apolipoprotein A-I and cholesterol by gradient gel electrophoresis

1983 • 92 citations

The influence of cellular and lipoprotein cholesterol contents on the flux of cholesterol between fibroblasts and high density lipoprotein.

1988 • 90 citations

Interaction of Apoprotein from Porcine High-Density Lipoprotein with Dimyristoyl Lecithin. 1. The Structure of the Complexes

1976 • 89 citations

Pre-β HDL: structure and metabolism

1996 • 89 citations

Nucleotide sequence of cloned cDNA of human apolipoprotein A-l

1983 • 88 citations

cDNA cloning of human apoA-I: Amino acid sequence of preproapoA-I

1983 • 85 citations

Molecular characterization of native and recombinant apolipoprotein A-IMilano dimer. The introduction of an interchain disulfide bridge remarkably alters the physicochemical properties of apolipoprotein A-I.

1994 • 85 citations

Structural Analysis of Apolipoprotein A-I: Limited Proteolysis of Methionine-Reduced and -Oxidized Lipid-Free and Lipid-Bound Human Apo A-I

1997 • 85 citations

Localization of an apolipoprotein A-I epitope critical for activation of lecithin-cholesterol acyltransferase.

1991 • 84 citations

The Influence of Sphingomyelin on the Structure and Function of Reconstituted High Density Lipoproteins

1996 • 84 citations

Interaction of Apoprotein from Porcine High-Density Lipoprotein with Dimyristoyl Lecithin. 2. Nature of Lipid-Protein Interaction

1976 • 82 citations

Investigation of the lipid domains and apolipoprotein orientation in reconstituted high density lipoproteins by fluorescence and IR methods.

1990 • 81 citations

PHOSPHOLIPID BINDING STUDIES WITH SYNTHETIC APOLIPOPROTEIN FRAGMENTS *

1980 • 80 citations

Apolipoprotein AIMilano. Accelerated binding and dissociation from lipids of a human apolipoprotein variant.

1985 • 78 citations

The Lipid-Free Structure of Apolipoprotein A-I: Effects of Amino-Terminal Deletions

1998 • 76 citations

Unique Epitope of Apolipoprotein A-I Expressed in Pre-.beta.-1 High-Density Lipoprotein and Its Role in the Catalyzed Efflux of Cellular Cholesterol

1994 • 76 citations

Phospholipid binding and lecithin-cholesterol acyltransferase activation properties of apolipoprotein A-I mutants

1995 • 76 citations

Effect of cholesterol on the charge and structure of apolipoprotein A-I in recombinant high density lipoprotein particles.

1993 • 76 citations

A new apolipoprotein Al variant, Trp50Arg, causes hereditary amyloidosis

1995 • 76 citations

The influence of apolipoprotein structure on the efflux of cellular free cholesterol to high density lipoprotein.

1994 • 75 citations

A mutation in the human apolipoprotein A-I gene. Dominant effect on the level and characteristics of plasma high density lipoproteins

1991 • 74 citations

Structural and functional properties of reconstituted high density lipoprotein discs prepared with six apolipoprotein A-I variants.

1991 • 74 citations

Structural Analysis of Apolipoprotein A-I: Effects of Amino- and Carboxy-Terminal Deletions on the Lipid-Free Structure

1998 • 74 citations

Hereditary nephropathic systemic amyloidosis caused by a novel variant apolipoprotein A-I

1998 • 73 citations

Studies of Synthetic Peptides of Human Apolipoprotein A-I Containing Tandem Amphipathic α-Helixes

1998 • 72 citations

Molecular pathways in the transformation of model discoidal lipoprotein complexes induced by lecithin: Cholesterol acyltransferase

1985 • 69 citations

The Hydrophobic Face Orientation of Apolipoprotein A-I Amphipathic Helix Domain 143–164 Regulates Lecithin:Cholesterol Acyltransferase Activation

1998 • 68 citations

Human apolipoprotein A-I polymorphism. Identification of amino acid substitutions in three electrophoretic variants of the Münster-3 type.

1984 • 67 citations

Apolipoprotein A-I conformation in discoidal particles: Evidence for alternate structures

1993 • 66 citations

Efflux of Cellular Cholesterol and Phospholipid to Apolipoprotein A-I Mutants

1996 • 65 citations

Deletion of the C-Terminal Domain of Apolipoprotein A-I Impairs Cell Surface Binding and Lipid Efflux in Macrophage

1999 • 63 citations

The replacement of arginine by cysteine at residue 151 in Apolipoprotein A-I produces a phenotype similar to that of Apolipoprotein A-I Milano

1997 • 63 citations

Structural and functional domains of apolipoprotein A-I within high density lipoproteins.

1993 • 63 citations

The Effect of Apolipoprotein A-II on the Structure and Function of Apolipoprotein A-I in a Homogeneous Reconstituted High Density Lipoprotein Particle

1997 • 62 citations

Structural Organization of the N-Terminal Domain of Apolipoprotein A-I: Studies of Tryptophan Mutants^†

1999 • 62 citations

Mechanism of dissociation of human apolipoprotein A-I from complexes with dimyristoylphosphatidylcholine as studied by guanidine hydrochloride denaturation

1982 • 62 citations

Apolipoprotein A‐I_Giessen (Pro¹⁴³→Arg)

1984 • 60 citations

Lipoprotein substrates for plasma cholesterol esterification

1985 • 60 citations

Apolipoprotein A-I Structural Modification and the Functionality of Reconstituted High Density Lipoprotein Particles in Cellular Cholesterol Efflux

1996 • 60 citations

Isolation of the human HDL apoprotein A1 gene

1982 • 60 citations

Differential effects of lecithin and cholesterol on the immunoreactivity and conformation of apolipoprotein A-I in high density lipoproteins

1991 • 59 citations

Compound Heterozygosity for a Structural Apolipoprotein A-I Variant, Apo A-I(L141R) _Pisa , and an Apolipoprotein A-I Null Allele in Patients With Absence of HDL Cholesterol, Corneal Opacifications, and Coronary Heart Disease

1996 • 59 citations

Localization of an apolipoprotein A-I epitope critical for lipoprotein-mediated cholesterol efflux from monocytic cells.

1994 • 58 citations

Effect of guanidine hydrochloride on the hydrodynamic and thermodynamic properties of human apolipoprotein A-I in solution.

1980 • 58 citations

Carboxyl-terminal Domain Truncation Alters Apolipoprotein A-I in Vivo Catabolism

1995 • 57 citations

Cell Cholesterol Efflux to Reconstituted High-Density Lipoproteins Containing the Apolipoprotein A-I_Milano Dimer

1999 • 55 citations

Apolipoprotein A-I domains involved in the activation of lecithin:cholesterol acyltransferase. Importance of the central domain

1993 • 54 citations

Reconstituted High-Density Lipoproteins with a Disulfide-Linked Apolipoprotein A-I Dimer: Evidence for Restricted Particle Size Heterogeneity

1997 • 54 citations

Mouse apolipoprotein A-IV gene: nucleotide sequence and induction by a high-lipid diet.

1986 • 54 citations

Interaction of reconstituted high density lipoprotein discs containing human apolipoprotein A-I (ApoA-I) variants with murine adipocytes and macrophages. Evidence for reduced cholesterol efflux promotion by apoA-I(Pro165–>Arg).

1993 • 53 citations

Cholesterol is poorly available for free apolipoprotein-mediated cellular lipid efflux from smooth muscle cells

1993 • 52 citations

Binding of lecithin:cholesterol acyltransferase to reconstituted high density lipoproteins is affected by their lipid but not apolipoprotein composition.

1994 • 52 citations

Alteration in Apolipoprotein A-I 22-Mer Repeat Order Results in a Decrease in Lecithin:Cholesterol Acyltransferase Reactivity

1997 • 49 citations

Apolipoprotein A-I _Fin

1997 • 49 citations

Binding Steps of Apolipoprotein A-I with Phospholipid Monolayers: Adsorption and Penetration

1998 • 48 citations

ApoA-I_Helsinki(Lys₁₀₇→0) Associated With Reduced HDL Cholesterol and LpA-I:A-II Deficiency

1995 • 47 citations

Identification of a Sequence of Apolipoprotein A-I Associated with the Efflux of Intracellular Cholesterol to Human Serum and Apolipoprotein A-I Containing Particles

1996 • 46 citations

Lipid transfers between reconstituted high density lipoprotein complexes and low density lipoproteins: effects of plasma protein factors

1988 • 46 citations

A Novel Homozygous Missense Mutation in the Apo A-I Gene With Apo A-I Deficiency

1998 • 45 citations

Isolation and specificity of rat lecithin : Cholesterol acyltransferase: Comparison with the human enzyme using reassembled high-density lipoproteins containing ether analogs of phosphatidylcholine

1985 • 42 citations

The covalent structure of apolipoprotein A-I from canine high density lipoproteins.

1982 • 42 citations

Activation of Lecithin Cholesterol Acyltransferase by a Disulfide-Linked Apolipoprotein A-I Dimer

1997 • 42 citations

Structural domain of apolipoprotein A-I involved in its interaction with cells

1994 • 41 citations

Cloning and structure analysis of the rat apolipoprotein A-1 cDNA

1984 • 40 citations

The salmon gene encoding apolipoprotein A-I: cDNA sequence, tissue expression and evolution

1991 • 40 citations

Distinct Central Amphipathic α-Helices in Apolipoprotein A-I Contribute to the in Vivo Maturation of High Density Lipoprotein by Either Activating Lecithin-Cholesterol Acyltransferase or Binding Lipids

2000 • 39 citations

Heterozygosity for apolipoprotein A-I(R160L)Oslo is associated with low levels of high density lipoprotein cholesterol and HDL-subclass LpA-I/A-II but normal levels of HDL-subclass LpA-I.

1997 • 39 citations

Effect of the Cholesterol Content of Reconstituted LpA-I on Lecithin:Cholesterol Acyltransferase Activity

1995 • 39 citations

Specific Phospholipid Association with Apolipoprotein A-I Stimulates Cholesterol Efflux from Human Fibroblasts

1996 • 38 citations

Apolipoprotein A-I _FIN (Leu159→Arg) Mutation Affects Lecithin

1997 • 38 citations

A natural apolipoprotein A-I variant, apoA-I (L141R)Pisa, interferes with the formation of alpha-high density lipoproteins (HDL) but not with the formation of pre beta 1-HDL and influences efflux of cholesterol into plasma

1997 • 37 citations

Characterization of the mouse apolipoprotein Apoa-1/Apoc-3 gene locus: Genomic, mRNA, and protein sequences with comparisons to other species

1992 • 36 citations

Effect of the surface lipid composition of reconstituted LPA-I on apolipoprotein A-I structure and lecithin:cholesterol acyltransferase activity

1998 • 36 citations

Limited proteolysis of high density lipoprotein abolishes its interaction with cell-surface binding sites that promote cholesterol efflux

1997 • 36 citations

Rabbit apolipoprotein A‐I mRNA and gene

1987 • 35 citations

Isolation and characterization of human apolipoprotein A-I Fukuoka (110 Glu → Lys). A novel apolipoprotein variant

1990 • 35 citations

Properties of lipid complexes with amphipathic helix-forming peptides

1989 • 34 citations

Lipid-peptide association and activation of lecithin:cholesterol acyltransferase. Effect of alpha-helicity.

1986 • 34 citations

Chicken apolipoprotein A-I: cDNA sequence, tissue expression and evolution

1987 • 33 citations

Importance of Central α-Helices of Human Apolipoprotein A-I in the Maturation of High-Density Lipoproteins

1998 • 32 citations

Structural and functional properties of natural and chemical variants of apolipoprotein A-I

1993 • 32 citations

Studies on Human Serum High-Density Lipoproteins

1976 • 32 citations

A Novel Mutant, ApoA-I Nichinan (Glu235→0), Is Associated With Low HDL Cholesterol Levels and Decreased Cholesterol Efflux From Cells

1999 • 29 citations

Deletion of Central α-Helices in Human Apolipoprotein A-I: Effect on Phospholipid Association

1997 • 29 citations

Role of the Arg123–Tyr166 Paired Helix of Apolipoprotein A-I in Lecithin:Cholesterol Acyltransferase Activation

1997 • 29 citations

Evolution of mammalian apolipoprotein A-I and conservation of antigenicity: correlation with primary and secondary structure

1997 • 27 citations

Crystallization of truncated human apolipoprotein A-I in a novel conformation

1999 • 27 citations

Deletion of Amino Acids Glu146→Arg160 in Human Apolipoprotein A-I (ApoA-I_Seattle) Alters Lecithin:Cholesterol Acyltransferase Activity and Recruitment of Cell Phospholipid

1998 • 27 citations

High density lipoprotein particle size restriction in apolipoprotein A-I(Milano) transgenic mice

1997 • 27 citations

Mouse Apolipoprotein AI. cDNA-Derived Primary Structure, Gene Organisation and Complete Nucleotide Sequence

1992 • 26 citations

Kinetics and mechanism of apolipoprotein A-I interaction with L-alpha-dimyristoylphosphatidylcholine vesicles.

1980 • 26 citations

Evidence That Apolipoprotein A-I _Milano Has Reduced Capacity, Compared With Wild-Type Apolipoprotein A-I, to Recruit Membrane Cholesterol

1997 • 25 citations

Effects of Deletion of the Carboxyl-terminal Domain of ApoA-I or of Its Substitution with Helices of ApoA-II on in Vitro and in Vivo Lipoprotein Association

1996 • 23 citations

Characterization of a new human apolipoprotein A-I Yame by direct sequencing of polymerase chain reaction-amplified DNA.

1991 • 23 citations

Helix-helix interactions in reconstituted high-density lipoproteins

1995 • 22 citations

Cloning and sequencing of bovine apolipoprotein A-I cDNA and molecular evolution of apolipoproteins A-I and B-100.

1990 • 22 citations

The primary structure of cynomolgus monkey apolipoprotein a-1 deduced from the cdna sequence: comparison to the human sequence

1986 • 21 citations

Characterization of the Apolipoprotein AI and CIII Genes in the Domestic Pig

1993 • 20 citations

Identification of homozygosity for a human apolipoprotein A-I variant.

1988 • 20 citations

Elevated triglycerides and low HDL cholesterol in transgenic mice expressing human apolipoprotein A-IMilano

1998 • 18 citations

Apolipoprotein A-I (Glu 198→Lys): A Mutant of the Major Apolipoprotein of High-Density Lipoproteins Occurring in a Family with Dyslipoproteinemia

1988 • 17 citations

Synthetic model peptides for apollpoproteins. II. Characterization of the discoidal complexes generated between phospholipids and synthetic model for apolipoproteins

1993 • 17 citations

Characterization of two new human apolipoprotein A-I variants: Apolipoprotein A-I Tsushima (Trp-108 → Arg) and A-I Hita (Ala-95→ Asp)

1994 • 16 citations

Role of the Carboxy‐Terminal Domain of Human Apolipoprotein AI in High‐Density‐Lipoprotein Metabolism

1997 • 15 citations

Role of Apolipoprotein A-I in Cholesterol Transfer between Lipoproteins

1995 • 15 citations

Identification of two apolipoprotein variants, A-I Karatsu (Tyr 100 → His) and A-I Kurume (His 162 → Gin)

1996 • 14 citations

Apolipoprotein A1 Baltimore (Arg10→Leu), a new ApoA1 variant

1990 • 13 citations

Role of glutamic acid residues 154, 155, and 165 of lecithin:cholesterol acyltransferase in cholesterol esterification and phospholipase A2 activities

1998 • 7 citations

Human apo A-I in transgenic mice is more efficient in activating lecithin: cholesterol acyltransferase than mouse apo A-I

1995 • 7 citations

Plasma lipid transport in the hedgehog: partial characterization of structure and function of apolipoprotein A-I.

1995 • 4 citations

Deleted Work

1955 • 0 citations