Cellular cholesterol efflux. Role of cell membrane kinetic pools and interaction with apolipoproteins AI, AII, and Cs.

An Algorithm for Least-Squares Estimation of Nonlinear Parameters

1963 • 29,357 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Fitting curves to data using nonlinear regression: a practical and nonmathematical review

1987 • 1,314 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 840 citations

Mechanisms and consequences of cellular cholesterol exchange and transfer

1987 • 547 citations

Cholesterol transport between cells and high-density lipoproteins

1991 • 451 citations

A rapid method for the isolation of L-cell surface membranes using an aqueous two-phase polymer system

1971 • 448 citations

Subcellular components: preparation and fractionation;

1972 • 421 citations

Cholesterol efflux from cultured adipose cells is mediated by LpAI particles but not by LpAI:AII particles

1987 • 335 citations

Interaction of free apolipoproteins with macrophages. Formation of high density lipoprotein-like lipoproteins and reduction of cellular cholesterol.

1991 • 331 citations

[32] Reconstitution of high-density lipoproteins

1986 • 316 citations

Distribution and Functions of Lecithin: Cholesterol Acyltransferase and Cholesteryl Ester Transfer Protein in Plasma Lipoproteins

1989 • 282 citations

Membrane Cholesterol Dynamics: Cholesterol Domains and Kinetic Pools

1991 • 262 citations

Pathophysiology of reverse cholesterol transport. Insights from inherited disorders of lipoprotein metabolism.

1989 • 241 citations

The role of apolipoprotein A-IV in reverse cholesterol transport studied with cultured cells and liposomes derived from an ether analog of phosphatidylcholine

1986 • 238 citations

Human apolipoprotein A-IV binds to apolipoprotein A-I/A-II receptor sites and promotes cholesterol efflux from adipose cells.

1990 • 212 citations

The bidirectional flux of cholesterol between cells and lipoproteins. Effects of phospholipid depletion of high density lipoprotein.

1986 • 186 citations

Mechanism of cholesterol efflux from cells. Effects of acceptor structure and concentration.

1982 • 184 citations

Hepatic lipase stimulates the uptake of high density lipoprotein cholesterol by hepatoma cells.

1983 • 155 citations

High density lipoprotein apolipoproteins mediate removal of sterol from intracellular pools but not from plasma membranes of cholesterol-loaded fibroblasts.

1991 • 150 citations

Sterol to Phospholipid Molar Ratios of L Cells with Qualitative and Quantitative Variations of Cellular Sterol

1974 • 132 citations

CHOLESTEROL METABOLISM IN THE MACROPHAGE

1972 • 128 citations

Rapid intracellular transport of LDL-derived cholesterol to the plasma membrane in cultured fibroblasts.

1990 • 108 citations

Intracellular sterol distribution in transfected mouse L-cell fibroblasts expressing rat liver fatty acid-binding protein.

1991 • 107 citations

Reverse cholesterol transport

1986 • 107 citations

Stimulation of esterified cholesterol accumulation in tissue culture cells exposed to high density lipoproteins enriched in free cholesterol.

1978 • 92 citations

The influence of cellular and lipoprotein cholesterol contents on the flux of cholesterol between fibroblasts and high density lipoprotein.

1988 • 90 citations

The efflux of lysosomal cholesterol from cells.

1990 • 89 citations

Role of apolipoproteins in cellular cholesterol efflux

1986 • 67 citations

A fluorescence and radiolabel study of sterol exchange between membranes

1988 • 58 citations

Time-resolved fluorescence investigation of membrane cholesterol heterogeneity and exchange

1988 • 55 citations

Kinetics of cholesterol and phospholipid exchange between Mycoplasma gallisepticum cells and lipid vesicles. Alterations in membrane cholesterol and protein content.

1984 • 51 citations

Role of the plasma membrane in the mechanism of cholesterol efflux from cells

1984 • 47 citations

Influence of apolipoproteins AI, AII, and Cs on the metabolism of membrane and lysosomal cholesterol in macrophages.

1991 • 45 citations

Metabolism of cholesteryl ester lipid droplets in a J774 macrophage foam cell model

1990 • 43 citations

Partially reassembled high density lipoproteins. Effects on cholesterol flux, synthesis, and esterification in normal human skin fibroblasts.

1986 • 43 citations

Triglyceride and cholesteryl ester hydrolysis in a cell culture model of smooth muscle foam cells.

1989 • 38 citations

Heterogeneity of rabbit intestine brush border plasma membrane cholesterol.

1982 • 37 citations

Cross-linking of apoproteins in high density lipoprotein by dimethylsuberimidate inhibits specific lipoprotein binding to membranes.

1988 • 27 citations

Effects of apolipoproteins on the kinetics of cholesterol exchange

1991 • 25 citations

Efflux of phospholipid from fibroblasts with normal and elevated levels of cholesterol

1991 • 24 citations

Lysosomal hydrolysis of lipids in a cell culture model of smooth muscle foam cells

1991 • 22 citations

Potential problems in the use of commercial preparations of radiolabeled cholesterol

1990 • 12 citations

Cholesterol transfer from mitochondrial membranes and cells to human and rat serum lipoprotein fractions.

1989 • 7 citations