On computer-assisted analysis of biological sequences: proline punctuation, consensus sequences, and apolipoprotein repeats.

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

The Art of Computer Programming

1968 • 16,727 citations

The Art of Computer Programming

1970 • 6,773 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Prediction of protein antigenic determinants from amino acid sequences.

1981 • 3,715 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Atlas of Protein Sequence and Structure, 1972.

1973 • 2,408 citations

Rapid similarity searches of nucleic acid and protein data banks.

1983 • 1,577 citations

The Solubility of Amino Acids and Two Glycine Peptides in Aqueous Ethanol and Dioxane Solutions

1971 • 1,417 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Biochemical Evolution

1977 • 1,283 citations

Evolution of genes and proteins.

1983 • 1,224 citations

[47] Establishing homologies in protein sequences

1983 • 1,187 citations

Use of Helical Wheels to Represent the Structures of Proteins and to Identify Segments with Helical Potential

1967 • 1,178 citations

Hydrophobicity of Amino Acid Residues in Globular Proteins

1985 • 1,168 citations

The nature of the accessible and buried surfaces in proteins

1976 • 1,151 citations

A simplified representation of protein conformations for rapid simulation of protein folding

1976 • 1,099 citations

Principles of Protein Structure

1979 • 1,090 citations

The helical hydrophobic moment: a measure of the amphiphilicity of a helix

1982 • 1,030 citations

THREE-DIMENSIONAL STRUCTURE OF MEMBRANE AND SURFACE PROTEINS

1984 • 959 citations

Similar Amino Acid Sequences: Chance or Common Ancestry?

1981 • 855 citations

Affinities of amino acid side chains for solvent water

1981 • 846 citations

Lipoprotein receptors and cholesterol homeostasis

1983 • 755 citations

Numerical Methods for Inferring Evolutionary Trees

1982 • 650 citations

The characterization of amino acid sequences in proteins by statistical methods

1968 • 550 citations

Amphiphilic Secondary Structure: Design of Peptide Hormones

1984 • 541 citations

Hemoglobin: Structure, function, evolution, and pathology

1984 • 507 citations

Surface tension of amino acid solutions: A hydrophobicity scale of the amino acid residues

1974 • 456 citations

On the use of sequence homologies to predict protein structure: identical pentapeptides can have completely different conformations.

1984 • 386 citations

How good are predictions of protein secondary structure?

1983 • 375 citations

Apolipoprotein multigene family: tandem organization of human apolipoprotein AI, CIII, and AIV genes.

1985 • 361 citations

Isolation, characterization, and mapping to chromosome 19 of the human apolipoprotein E gene.

1985 • 352 citations

Activation of lecithin: cholesterol acyltransferase by human apolipoprotein A-IV.

1985 • 339 citations

Studies of synthetic peptide analogs of the amphipathic helix. Structure of complexes with dimyristoyl phosphatidylcholine.

1985 • 314 citations

Secondary structures of proteins and peptides in amphiphilic environments. (A review).

1983 • 299 citations

Chemical Paleogenetics. Molecular "Restoration Studies" of Extinct Forms of Life.

1963 • 297 citations

Nucleotide sequence and structure of the human apolipoprotein E gene.

1985 • 289 citations

The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments.

1983 • 276 citations

Isolation and characterization of the human apolipoprotein A-I gene.

1983 • 243 citations

Amino acid properties and side-chain orientation in proteins: A cross correlation approach

1975 • 232 citations

The receptor-binding domain of human apolipoprotein E. Monoclonal antibody inhibition of binding.

1983 • 226 citations

Structure and evolution of the apolipoprotein multigene family

1986 • 214 citations

The mechanism of activation of lecithin:cholesterol acyltransferase by apolipoprotein A-I and an amphiphilic peptide.

1980 • 204 citations

Characterization of the apolipoproteins of rat plasma lipoproteins

1977 • 190 citations

Repeating Sequences and Gene Duplication in Proteins

1989 • 181 citations

SEQ: a nucleotide sequence analysis and recombination system

1982 • 179 citations

Evolution and the Tertiary Structure of Proteins

1984 • 173 citations

Determining globular protein stability: guanidine hydrochloride denaturation of myoglobin

1979 • 157 citations

The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III.

1986 • 156 citations

PHYLOGENIES CONSTRAINED BY THE CROSSOVER PROCESS AS ILLUSTRATED BY HUMAN HEMOGLOBINS AND A THIRTEEN-CYCLE, ELEVEN-AMINO-ACID REPEAT IN HUMAN APOLIPOPROTEIN A-I

1977 • 152 citations

Apolipoproteins and the structural organization of plasma lipoproteins: human plasma high density lipoprotein-3.

1979 • 135 citations

Statistical Analysis of DNA Sequence Data.

1984 • 122 citations

Repeated helical pattern in apolipoprotein-A-I

1977 • 120 citations

Handbook of Biochemistry. Selected Data for Molecular Biology

1970 • 110 citations

Rat apolipoprotein A-IV contains 13 tandem repetitions of a 22-amino acid segment with amphipathic helical potential.

1984 • 107 citations

Studies of synthetic peptide analogs of the amphipathic helix. Correlation of structure with function.

1985 • 102 citations

Comparative analysis of repeated sequences in rat apolipoproteins A-I, A-IV, and E.

1985 • 95 citations

Evolution of apolipoprotein E: mouse sequence and evidence for an 11-nucleotide ancestral unit.

1985 • 92 citations

Of mice and men: Fossil-based divergence dates and molecular “clocks”

1980 • 89 citations

Nucleotide sequence of cloned cDNA of human apolipoprotein A-l

1983 • 88 citations

Evolution of lipoproteins deduced from protein sequence data

1977 • 83 citations

On the statistical significance of nucleic add similarities

1984 • 82 citations

The structure of human density lipoprotein: A study of the effect of phospholipase A and trypsin on its components and of the behavior of the lipid and protein moieties at the air-water interphase

1969 • 80 citations

Chain length-function correlation of amphiphilic peptides. Synthesis and surface properties of a tetratetracontapeptide segment of apolipoprotein A-I.

1980 • 76 citations

A synthetic amphiphilic helical docosapeptide with the surface properties of plasma apolipoprotein A-I

1979 • 76 citations

Structural properties and lipid binding of human apolipoprotein A-IV.

1985 • 74 citations

The use of polymer-bound oximes for the synthesis of large peptides usable in segment condensation: synthesis of a 44 amino acid amphiphilic peptide model of apolipoprotein A-1

1985 • 74 citations

Analysis of gene duplication repeats in the myosin rod

1983 • 70 citations

Evolution of the apolipoproteins. Structure of the rat apo-A-IV gene and its relationship to the human genes for apo-A-I, C-III, and E.

1986 • 69 citations

Amphipathic helixes and plasma lipoproteins: A computer study

1977 • 65 citations

Homology in protein sequences expressed by correlation coefficients

1981 • 62 citations

Effect of guanidine hydrochloride on the hydrodynamic and thermodynamic properties of human apolipoprotein A-I in solution.

1980 • 58 citations

On the conformation of proteins: Hydrophobic ordering of strands in β-pleated sheets

1977 • 58 citations

Repeats of base oligomers as the primordial coding sequences of the primeval earth and their vestiges in modern genes

1984 • 57 citations

An analysis of non-bonded energy of proteins

1977 • 53 citations

Evolution of the albumin: α-fetoprotein ancestral gene from the amplification of a 27 nucleotide sequence

1984 • 49 citations

Isolation and lipid-binding properties of rat apolipoprotein A-IV

1985 • 44 citations

Isolation and specificity of rat lecithin : Cholesterol acyltransferase: Comparison with the human enzyme using reassembled high-density lipoproteins containing ether analogs of phosphatidylcholine

1985 • 42 citations

The contribution of α‐helices to the surface activities of proteins

1984 • 36 citations

Genetics: Gene conversion in the absence of reciprocal recombination

1984 • 36 citations

Mechanism of lipid-protein interaction in lipoproteins. A synthetic peptide-lecithin vesicle model

1978 • 35 citations

Lipid-peptide association and activation of lecithin:cholesterol acyltransferase. Effect of alpha-helicity.

1986 • 34 citations

The helical hydrophobic moments and surface activities of serum apolipoproteins

1983 • 33 citations

Comparison of the human apolipoprotein genes

1985 • 32 citations

Helical amphipathic moment: application to plasma lipoproteins

1983 • 28 citations

Conformational properties of human and rat apolipoprotein A-IV.

1985 • 25 citations

In vivo interaction of synthetic acylated apopeptides with high density lipoproteins in rat.

1986 • 23 citations

Helical length distribution from protein crystallographic data.

1976 • 13 citations

[44] Rat apolipoprotein A-IV: Application of computational methods for studying the structure, function, and evolution of a protein

1986 • 12 citations

Local sequence patterns of hydrophobicity and solvent accessibility in soluble globular proteins

1987 • 11 citations

[45] Detecting internally repeated sequences and inferring the history of duplication

1986 • 10 citations

Deleted Work

1955 • 0 citations