PARP‐1 gene disruption in mice preferentially protects males from perinatal brain injury

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1981 • 2,073 citations

Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor

2002 • 1,771 citations

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

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Physiological and pathophysiological roles of excitatory amino acids during central nervous system development

1990 • 1,427 citations

Role of poly(ADP-ribose) formation in DNA repair

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Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

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Poly(ADP-Ribose) in the Cellular Response to DNA Damage

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Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease.

1995 • 767 citations

Role of poly(ADP-ribose) synthetase in inflammation and ischaemia–reperfusion

1998 • 687 citations

Ischemic Brain Injury is Mediated by the Activation of Poly(ADP-Ribose)Polymerase

1997 • 624 citations

Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury.

1998 • 514 citations

Apoptosis Has a Prolonged Role in the Neurodegeneration after Hypoxic Ischemia in the Newborn Rat

2000 • 418 citations

Estrogen as a Neuroprotectant in Stroke

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Brain damage, sex hormones and recovery: a new role for progesterone and estrogen?

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Involvement of Caspase-3 in Cell Death after Hypoxia–Ischemia Declines during Brain Maturation

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Protective Effects of Moderate Hypothermia after Neonatal Hypoxia-Ischemia: Short- and Long-Term Outcome

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Involvement of apoptosis‐inducing factor in neuronal death after hypoxia‐ischemia in the neonatal rat brain

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NAD⁺ as a metabolic link between DNA damage and cell death

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Strain-related brain injury in neonatal mice subjected to hypoxia–ischemia

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Monoclonal antibodies to poly(adenosine diphosphate ribose) recognize different structures

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NMDA But Not Non-NMDA Excitotoxicity is Mediated by Poly(ADP-Ribose) Polymerase

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Poly(ADP-ribose) Polymerase-1 in the Nervous System

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Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity

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Cellular Responses to DNA Damage in the Absence of Poly(ADP-ribose) Polymerase

1998 • 190 citations

Selective, Reversible Caspase-3 Inhibitor Is Neuroprotective and Reveals Distinct Pathways of Cell Death after Neonatal Hypoxic-ischemic Brain Injury

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Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1

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Relation between delayed impairment of cerebral energy metabolism and infarction following transient focal hypoxia-ischaemia in the developing brain

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Caspase-3 Activation after Neonatal Rat Cerebral Hypoxia-Ischemia

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Poly(ADP-Ribose) Polymerase Impairs Early and Long-Term Experimental Stroke Recovery

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Correlation Between Caspase‐3 Activation and Three Different Markers of DNA Damage in Neonatal Cerebral Hypoxia‐Ischemia

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Mitochondrial Function and Energy Metabolism after Hypoxia—Ischemia in the Immature Rat Brain: Involvement of NMDA-Receptors

1998 • 114 citations

Activation of Poly(ADP‐Ribose) Polymerase in the Rat Hippocampus May Contribute to Cellular Recovery Following Sublethal Transient Global Ischemia

2000 • 106 citations

Poly(ADP‐Ribose) Synthase Inhibition Reduces Ischemic Injury and Inflammation in Neonatal Rat Brain

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[19] Tissue NAD as a biochemical measure of niacin status in humans

1997 • 92 citations

Brain sexual differentiation and gonadotropins secretion in the rat.

1997 • 86 citations

Temporal Changes of Regional Glucose Use, Blood Flow, and Microtubule-Associated Protein 2 Immunostaining after Hypoxia—Ischemia in the Immature Rat Brain

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Carotid ligation in gerbils. Influence of age, sex, and gonads.

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The neuroprotective effect of cerebral poly(ADP-ribose)polymerase inhibition in a rat model of global ischemia

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Immunological determination and size characterization of poly(ADP-ribose) synthesized in vitro and in vivo

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Sexual dimorphism in the developmental regulation of brain aromatase

1995 • 50 citations

Immunodot Blot Method for the Detection of Poly(ADP-ribose) Synthesizedin Vitroandin Vivo

1998 • 47 citations

NMDA Receptor–Dependent Increase of Cerebral Glucose Utilization after Hypoxia–Ischemia in the Immature Rat

1996 • 40 citations

Apoptosis Detection in Brain Using Low-Magnification Dark-Field Microscopy

1999 • 15 citations