The Cell Surface Membrane Proteins Cdo and Boc Are Components and Targets of the Hedgehog Signaling Pathway and Feedback Network in Mice

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

1996 • 3,041 citations

Hedgehog signaling in animal development: paradigms and principles

2001 • 2,919 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

Neuronal specification in the spinal cord: inductive signals and transcriptional codes

2000 • 2,051 citations

A series of normal stages in the development of the chick embryo

1992 • 1,860 citations

Altered Neural Cell Fates and Medulloblastoma in Mouse patched Mutants

1997 • 1,695 citations

In situ hybridization; a practical approach

1993 • 1,247 citations

A Homeodomain Protein Code Specifies Progenitor Cell Identity and Neuronal Fate in the Ventral Neural Tube

2000 • 1,077 citations

Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling

1997 • 1,019 citations

1 Developmental roles and clinical significance of Hedgehog signaling

2003 • 896 citations

Teratogen-Mediated Inhibition of Target Tissue Response to Shh Signaling

1998 • 839 citations

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

1999 • 772 citations

Sonic hedgehog signaling is essential for hair development

1998 • 742 citations

A mitogen gradient of dorsal midline Wnts organizes growth in the CNS

2002 • 672 citations

Smoothened Mutants Reveal Redundant Roles for Shh and Ihh Signaling Including Regulation of L/R Asymmetry by the Mouse Node

2001 • 599 citations

In situ hybridization; a practical approach

1993 • 599 citations

Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia

2004 • 592 citations

Specification of neuronal fates in the ventral neural tube

2001 • 530 citations

Identification of Hedgehog Pathway Components by RNAi in Drosophila Cultured Cells

2003 • 518 citations

Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice

1998 • 448 citations

A Hedgehog-Insensitive Form of Patched Provides Evidence for Direct Long-Range Morphogen Activity of Sonic Hedgehog in the Neural Tube

2001 • 364 citations

Proteolytic Processing Yields Two Secreted Forms of Sonic hedgehog

1995 • 309 citations

The Whereabouts of a Morphogen: Direct Evidence for Short- and Graded Long-Range Activity of Hedgehog Signaling Peptides

2001 • 288 citations

Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization

2002 • 280 citations

A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube

2005 • 270 citations

A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord

2002 • 257 citations

Cdo Functions at Multiple Points in the Sonic Hedgehog Pathway, and Cdo-Deficient Mice Accurately Model Human Holoprosencephaly

2006 • 252 citations

Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1

2004 • 223 citations

Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite

2001 • 171 citations

ELF-2, a New Member of the Eph Ligand Family, Is Segmentally Expressed in Mouse Embryos in the Region of the Hindbrain and Newly Forming Somites

1995 • 155 citations

BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation

2002 • 143 citations

Distinct regulators ofShhtranscription in the floor plate and notochord indicate separate origins for these tissues in the mouse node

2003 • 124 citations

Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos

2000 • 113 citations

Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand

2004 • 108 citations

Microform Holoprosencephaly in Mice that Lack the Ig Superfamily Member Cdon

2003 • 108 citations

CDO: An Oncogene-, Serum-, and Anchorage-regulated Member of the Ig/Fibronectin Type III Repeat Family

1997 • 90 citations

Developmental expression pattern of thecdo gene

2000 • 46 citations

Expression of the boc gene during murine embryogenesis

2002 • 43 citations